Elsevier

Tubercle

Volume 70, Issue 3, September 1989, Pages 207-210

Original article
Resistance to antituberculosis drugs in Riyadh, Saudi Arabia

https://doi.org/10.1016/0041-3879(89)90052-4Get rights and content

Abstract

The prevalence of resistance to antituberculosis drugs in Riyadh was found to be 21.3%, while the rate of primary drug resistance was 11.5%. Resistance to isoniazid was the most common (19.4%) followed by rifampicin and streptomycin. The prevalence of primary and acquired rifampicin resistance was 3 and 33.7% respectively. The majority of isolates from patients with acquired resistance to rifampicin were resistant also to isoniazid.

Résumé

La prévalence de la resistance vis-a-vis des médicaments antituberculeux à Riyad a été trouvée de 21,3% et le taux de résistance primaire de 11,5 %. La résistance à l'isoniazide était la plus fréquente (19,4%), suivie par la résistance à la rifampicine et à la streptomycine. La prévalence des résistances primaire et acquise à la rifampicine était de 3 et 33,7% respectivement. La plupart des isolats provenant de malades qui avaient une résistance acquise à la rifampicine étaient aussi résistants à l'isoniazide.

Resumen

En Riyadh se encontró una prevalencia de resistencia a los medicamentos antituberculosos de 21,3% y la tasa de resistencia primaria era de 11,5%. La resistencia a la isoniacida era la más frecuente (19,4%), seguida por la resistencia a la rifampicina y a la estreptomicina. La prevalencia de la resistencia primaria y adquirida a la rifampicina era de 3 y 33,7% respectivamente. La mayor pane de los aislados provenientes de pacientes con resistencia adquirida a la rifampicina eran también resistentes a la isoniacida.

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