Sarcophine—a new toxin from the soft coral Sarcophyton glaucum (Alcyonaria)
References (8)
Tissue sulfhydryl groups
Archs Biochem. Biophys.
(1959)Littoral fauna of the Red Sea: the population of non-scleractinian anthozoans of shallow waters of the Red Sea (Eilat)
Mar. Biol.
(1970)Ecology and distribution of the benthic fauna in the shallow waters of the Red Sea
Mar. Biol.
(1971)Ecology of the coral reefs in the Gulf of Aqaba (Red Sea) influenced by pollution
Oecologia
(1973)
Cited by (84)
A new cembranoid from the Red Sea soft coral Sarcophyton acutum
2024, Natural Product ResearchXimaoglaucumins A − F, new cembranoids with anti-inflammatory activities from the South China Sea soft coral Sarcophyton glaucum
2021, Bioorganic and Medicinal ChemistryCitation Excerpt :The appearance of an oxygenated quaternary carbon signal at δC 73.2 and a methyl signal at δC 28.9, accompanying with the disappearance of the typical 13C NMR signals for the exocyclic olefin at Δ8,19 in 2 clearly indicated the hydroxylation occurred at C-8. Further, the characteristic NMR signals of a trans-disubstituted double bond [δH 5.71 (1H, dt, J = 15.6, 6.6 Hz, H-6), 5.59 (1H, d, J = 15.6 Hz, H-7)] in 3, combined with the clear proton sequence of H2-5 (δH 2.80, 2.69)/H-6 (δH 5.71)/H-7 (δH 5.59) displayed in the 1H-1H COSY spectrum, suggested the location of the double bond at Δ6,7 in 3. The HMBC cross peaks (Fig. 4) observed from H-6/H-10 (δH 2.16) to C-8 (δC 73.2), and from H3-19 (δH 1.33) to C-7 (δC 139.4)/C-8 confirmed the presence of the partial structure from C-6 to C-8 in 3.
Sarcophine and (7S, 8R)-dihydroxydeepoxysarcophine from the Red Sea soft coral Sarcophyton glaucum as in vitro and in vivo modulators of glycine receptors
2020, NeuroToxicologyCitation Excerpt :These animals live exposed to predators in their environment, thus they rely mainly on their essential toxic secondary metabolites to repel potential attackers (Bilasy et al., 2006). Ever since its discovery, SN has undergone extensive investigations for promising biological activities, especially for its antitumour potential (Ne’eman et al., 1974; Liang and Guo, 2013; Zubair et al., 2016; Chao et al., 2017). However, the toxicity of SN remains an obstacle against introducing it for human clinical trials (Bernstein et al., 1974).
Sarcoglaucins A-I, new antifouling cembrane-type diterpenes from the South China Sea soft coral: Sarcophyton glaucum
2019, Organic Chemistry FrontiersThe pro-apoptotic activity of sinueracasbanone D isolated from Sinularia Leptoclados in hepatocellular carcinoma cells
2023, Environmental Science and Pollution Research