Elsevier

Life Sciences

Volume 44, Issue 3, 1989, Pages 175-186
Life Sciences

Aids research communication
Minireview Magnetically controlled targeted micro-carrier systems

https://doi.org/10.1016/0024-3205(89)90593-6Get rights and content

Abstract

Magnetically controlled targeted drug delivery systems are aimed at concentrating drugs at a defined target site, with the aid of a magnetic field. This technique has been developed specifically for directing drugs away from the reticuloendothelial system (RES). Literature on this topic suggests that these delivery systems are capable of altering the distribution of chemotherapeutic agents in the body. Hence these delivery devices offer the possibility of improving the therapeutic efficacy of the associated drugs. This paper reviews the work done to date towards the development and evaluation of biodegradable and non-biodegradable magnetic targeted drug delivery systems and outlines their future prospects and limitations in cancer chemotherapy.

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