Restoration of brain growth in fetal sheep after iodized oil administration to pregnant iodine-deficient ewes
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LB1 and LB6 Homo floresiensis are not modern human (Homo sapiens) cretins
2012, Journal of Human EvolutionCitation Excerpt :Myxedematous cretins usually have less severe intellectual impairment, head dimensions that are large relative to their dwarfed stature, and brain weights that are also in the normal human range (Delange and Ermans, 1971; Delange et al., 1972a; Boyages et al., 1988a; van den Broeck et al., 1993; Obendorf et al., 2008: Supplementary online tables and figures) (Fig. 10). Data on cretin brain mass are consistent with the results of animal models (rats, sheep and marmosets) that examined the impact of severely iodine deficient diets on foetal brain development (Potter et al., 1982, 1984; Li et al., 1986; Mano et al., 1987). There were indications of delayed brain maturation, increased neuronal density in the cerebral hemispheres, and cellular changes in the cerebellum, but only a slight reduction in body weight and brain weight in utero.
Iodine Deficiency and the Brain: An Overview
2009, Comprehensive Handbook of Iodine: Nutritional, Biochemical, Pathological and Therapeutic AspectsIodine Deficiency and the Brain: An Overview
2009, Comprehensive Handbook of IodineThe effects of intrauterine growth retardation on synaptogenesis and mitochondrial formation in the cerebral and cerebellar cortices of fetal sheep
1988, International Journal of Developmental Neuroscience