A comparative study of central visual field changes induced by sarin vapour and physostigmine eye drops

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Abstract

A Friedmann visual field analyser was used to study the threshold luminance of multiple stimuli within the central visual field in human volunteers made miotic by exposure to sarin vapour. The observations were compared, in the same subjects, with the effects produced with an identical degree of miosis induced by the instillation of physostigmine. The results suggest that exposure to sarin vapour may affect the visual threshold, influencing cone more than rod function, possibly by modifying acetylcholine-mediated neurotransmission within the retina or central visual pathways.

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