A study of particulate intestinal absorption and hepatocellular uptake: Use of polystyrene latex particles
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2022, Journal of Hazardous MaterialsCitation Excerpt :It has been shown that MP can pass the epithelial layer between enterocytes in a paracellular manner (Volkheimer, 1975). For the transcellular translocation of microparticles, including MP, the uptake by M-cells into the Peyer’s patches (lymphoid follicles in the small intestine) plays a significant role (Carr et al., 2012; Sanders and Ashworth, 1961; Lefevre et al., 1989; Jani et al., 1989; Des Rieux et al., 2005). Furthermore, it was shown that the translocation efficiency strongly depends on particles size (Carr et al., 2012; Jani et al., 1990).
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2020, Colloids and Surfaces B: BiointerfacesCitation Excerpt :As early as 1960, Payne et al. [53] revealed the uptake of small resin particles by the alimentary canal of the calf. Next year, Sanders et al. [54] demonstrated particulate intestinal absorption and hepatocellular uptake of PS latex particles. Since then, evidences on the uptake and absorption of particles by the GI tract have been presented by researchers worldwide [55–60].