Interaction of carbohydrates with dry dipalmitoylphosphatidylcholine
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Freeze-drying cycle optimization for the rapid preservation of protein-loaded liposomal formulations
2020, International Journal of PharmaceuticsCharacteristic responses of a 1,2-dipalmitoleoyl-sn-glycero-3- phosphoethanolamine molecular layer depending on the number of CH(OH) groups in polyols
2019, Colloids and Surfaces A: Physicochemical and Engineering AspectsCitation Excerpt :The wavenumber of the maximum intensity for pure DPoPE decreased as the m value was increased, and the dependence of the wavenumber on m was slightly higher at 313 K than at 315 K. Based on the experimental results presented above and related papers [8,14,23,31], we discuss the different responses of DPoPE depending on the chemical structure of the added polyol. Disalvo et al. reported the positive adsorption of erythritol into a lipid bilayer [32].
DMSO-induced perturbation of thermotropic properties of cholesterol-containing DPPC liposomes
2016, Biochimica et Biophysica Acta - BiomembranesCitation Excerpt :This effect is not induced by direct interaction with the hydrophobic part of phospholipid units since the sulfoxide is not likely to reside in the inner region of the bilayer [46]. As previously reported for both artificial and cell membranes [54–58], dehydration of polar groups on the surface of the bilayer can modify the arrangement of phospholipid molecules and stabilize the gel phase of the membrane. In fact, we evidence a more rigid arrangement of acyl chains as related to a reduced hydration of phosphate groups both in the gel and in the liquid crystalline phases of DPPC and DPPC/Chol vesicles.
Characteristic responses of a phospholipid molecular layer to polyols
2015, Colloids and Surfaces B: BiointerfacesArbutin's suppression of cryodamage in goat sperm and its mechanism of cryoprotection
2011, TheriogenologyCitation Excerpt :Furthermore, arbutin is known to have the antioxidant properties of a membrane lipid [21], as well as inhibitory effects against phospholipase A2 (PLA2) [20]. Trehalose is a disaccharide that has been extensively used as a cryoprotectant [22,23], as well as for drying [24]. In addition, we previously studied the effects of trehalose on cryopreservation of goat sperm, demonstrating its effects on the fluidity of the goat sperm membrane [25].
Trehalose: Current use and future applications
2011, Journal of Pharmaceutical Sciences