Abstract
Bacterial infections associated with biomaterials are currently regarded as the most severe and devastating complications for their use as implants and medical devices. Biofilm is the major cause of bacterial infections associated with biomaterials. This review presents the biofilm formation, associated infections, and their current prevention strategies. The loss of efficacy of conventional antibiotic therapies leads to the development of antibacterial surfaces and coatings. Multifunctional surfaces and coatings can prevent biofilm formation and can become a novel strategy to fight biofilm. In this review, attention is focused on different surface modification techniques, surface coatings, and their current manufacturing methods to produce antibacterial biomaterials using surface engineering and nanobiotechnology.
Lay Summary
Implants and medical devices are widely used in present day medicine in different ways. Implant infections caused by bacteria lead to serious complications and failure of implants. Bacteria attach to the surface of implants and form colonies called biofilm which is a major cause of implant-associated bacterial infections. The conventional antibiotic therapies present various limitations in biofilm treatment. Promising strategies based on material science and surface engineering are being developed to address these limitations. This review article discusses the different non-conventional methods to treat biofilms. A specific discussion involves surface modifications, surface coatings, and their interactions with biofilm-causing bacteria. Establishing standardized procedures for testing toxicity and tissue integration of these surfaces and coatings will guide the future strategies in developing infection-resistant biomaterials.
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Gallieni M, Giordano A, Pinerolo C, Cariati M. Type of peritoneal dialysis catheter and outcomes. J Vasc Access. 2015;16(9_suppl):S68–72. https://doi.org/10.5301/jva.5000369.
Lawrence EL, Turner I. Materials for urinary catheters: a review of their history and development in the UK. Med Eng Phys. 2005;27:443–53. https://doi.org/10.1016/j.medengphy.2004.12.013.
Timsit JF, Dubois Y, Minet C, Bonadona A, Lugosi M, Ara-Somohano C, et al. New materials and devices for preventing catheter-related infections. Ann Intensive Care. 2011;1:34. https://doi.org/10.1186/2110-5820-1-34.
Mani G, Feldman MD, Patel D, Agrawal CM. Coronary stents: a materials perspective. Biomaterials. 2007;28(9):1689–710. https://doi.org/10.1016/j.biomaterials.2006.11.042.
Mancini D, Colombo PC. Left Ventricular Assist Devices: A rapidly evolving alternative to transplant. J Am Coll Cardiol. 2015;65(23):2542–55. https://doi.org/10.1016/j.jacc.2015.04.039.
Paglia E, Carter J. Cardiac pacemakers. Hosp Med Clin. 2017;6(3):374–96. https://doi.org/10.1016/j.ehmc.2017.04.007.
Jaffer IH, Whitlock RP. A mechanical heart valve is the best choice. Heart Asia. 2016;8:62–4. https://doi.org/10.1136/heartasia-2015-010660.
Pashneh-Tala S, MacNeil S, Claeyssens F. Tissue Eng B Rev. 2016. https://doi.org/10.1089/ten.teb.2015.0100.
Ferguson RJ, Palmer AJR, Taylor A, Porter ML, Malchau H, Glyn-Jones S. Hip and knee replacement 1 Hip replacement. Lancet. 2018:1662–71. https://doi.org/10.1016/S0140-6736(18)31777-X.
Andrew J, Price AA, Troelsen A, Katz JN, Hooper G, Gray A, et al. Hip and knee replacement 2 Knee replacement. Lancet. 2018:1672–82. https://doi.org/10.1016/S0140-6736(18)32344-4.
Mihra S. Taljanovic, Marci D. Jones, John T. Ruth, James B. Benjamin, Joseph E. Sheppard, Tim B. Hunter, Fracture fixation, RadioGraphics, 2003, pp. 1569–1590. https://doi.org/10.1148/rg.236035159.
Osman RB, Swain MV. A critical review of dental implant materials with an emphasis on titanium versus zirconia. Materials. 2015:932–58. https://doi.org/10.3390/ma8030932.
Bilsel Y, Abci I. The search for ideal hernia repair; mesh materials and types. Int J Surg. 2012:317–21. https://doi.org/10.1016/j.ijsu.2012.05.002.
Stöver T, Lenarz T. Biomaterials in cochlear implants. GMS Curr Top Otorhinolaryngol Head Neck Surg. 2009;8:Doc10. https://doi.org/10.3205/cto000062.
Zaki M, Pardo J, Carracedo G. A review of international medical device regulations: contact lenses and lens care solutions. Cont Lens Anterior Eye. 2019;42(2):136–46. https://doi.org/10.1016/j.clae.2018.11.001.
Alio J, Plaza-Puche AB, Férnandez-Buenaga R, Pikkel J, Maldonado M. Multifocal intraocular lenses: an overview. Surv Ophthalmol. 2017. https://doi.org/10.1016/j.survophthal.2017.03.005.
Rodriguez KM, Kohn TP, Davis AB, Hakky TS. Penile implants: a look into the future. Transl Androl Urol. 2017;6(Suppl 5):S860–6. https://doi.org/10.21037/tau.2017.05.28.
Maxwell GP, Gabriel A. Breast implant design. Gland Surg. 2017;6(2):148–53. https://doi.org/10.21037/gs.2016.11.09.
Singh R, Hawkins W. Sutures, ligatures and knots. Surgery (Oxford). 2017;35(4):185–9. https://doi.org/10.1016/j.mpsur.2017.01.017.
Sutherland IW. The biofilm matrix – an immobilized but dynamic microbial environment. Trends Microbiol. 2001;9(5):222–7. https://doi.org/10.1016/S0966-842X(01)02012-1.
Luppens SB, Reij MW, van der Heijden RW, Rombouts FM, Abee T. Development of a standard test to assess the resistance of Staphylococcus aureus biofilm cells to disinfectants. Appl Environ Microbiol. 2002;68(9):4194–200. https://doi.org/10.1128/aem.68.9.4194-4200.2002.
Gristina AG, Hobgood CD, Webb LX, Myrvik QN. Adhesive colonization of biomaterials and antibiotic resistance. Biomaterials. 1987;8(6):423–6. https://doi.org/10.1016/0142-9612(87)90077-9.
Prosser BL, Taylor D, Dix BA, Cleeland R. Method of evaluating effects of antibiotics on bacterial biofilm. Antimicrob Agents Chemother. 1987;31(10):1502–6. https://doi.org/10.1128/aac.31.10.1502.
Rice L. Progress and challenges in implementing the research on ESKAPE pathogens. Infect Control Hosp Epidemiol. 2010;31(S1):S7–S10. https://doi.org/10.1086/655995.
Renner LD, Weibel DB. Physicochemical regulation of biofilm formation. MRS Bull. 2011;36(5):347–55. https://doi.org/10.1557/mrs.2011.65.
Toyofuku M, Inaba T, Kiyokawa T, Obana N, Yawata Y, Nomura N. Environmental factors that shape biofilm formation. Biosci Biotechnol Biochem. 2016;80(1):7–12. https://doi.org/10.1080/09168451.2015.1058701.
Peters G, Locci R, Pulverer G. Adherence and growth of coagulase-negative staphylococci on surfaces of intravenous catheters. J Infect Dis. 1982;146(4):479–82. https://doi.org/10.1093/infdis/146.4.479.
von Eiff C, Peters G, Heilmann C. Pathogenesis of infections due to coagulasenegative staphylococci. Lancet Infect Dis. 2002;2(11):677–85. https://doi.org/10.1016/S1473-3099(02)00438-3.
Espersen F, Wilkinson BJ, Gahrn-Hansen B, Rosdahl VT, Clemmensen I. Attachment of staphylococci to silicone catheters in vitro. APMIS. 1990;98:471–8. https://doi.org/10.1111/j.1699-0463.1990.tb01059.x.
Herrmann M, Vaudaux PE, Pittet D, Auckenthaler R, Lew PD, Perdreau FS, et al. Fibronectin, fibrinogen, and laminin act as mediators of adherence of clinical staphylococcal isolates to foreign material. J Infect Dis. 1988;158(4):693–701. https://doi.org/10.1093/infdis/158.4.693.
Arciola CR, Campoccia D, Ravaioli S, Montanaro L. Polysaccharide intercellular adhesin in biofilm: structural and regulatory aspects. Front Cell Infect Microbiol. 2015;5:7. https://doi.org/10.3389/fcimb.2015.00007.
Cucarella C, Tormo MA, Knecht E, Amorena B, Lasa I, Foster TJ, et al. Expression of the biofilm-associated protein interferes with host protein receptors of Staphylococcus aureus and alters the infective process. Infect Immun. 2002;70(6):3180–6. https://doi.org/10.1128/iai.70.6.3180-3186.2002.
Geraci J, Neubauer S, Pöllath C, Hansen U, Rizzo F, Krafft C, et al. The Staphylococcus aureus extracellular matrix protein (Emp) has a fibrous structure and binds to different extracellular matrices. Sci Rep. 2017;7(1):13665. https://doi.org/10.1038/s41598-017-14168-4.
Alabdullatif M, Ramirez-Arcos S. Biofilm-associated accumulation-associated protein (Aap): a contributing factor to the predominant growth of Staphylococcus epidermidis in platelet concentrates. Vox Sang. 2019;114:28–37. https://doi.org/10.1111/vox.12729.
Tormo MÁ, Martí M, Valle J, Manna AC, Cheung AL, Lasa I, et al. SarA is an essential positive regulator of Staphylococcus epidermidis biofilm development. J Bacteriol. 2005;187(7):2348–56. https://doi.org/10.1128/JB.187.7.2348-2356.200.
Rupp CJ, Fux CA, Stoodley P. Viscoelasticity of Staphylococcus aureus biofilms in response to fluid shear allows resistance to detachment and facilitates rolling migration. Appl Environ Microbiol. 2005;71(4):2175–8. https://doi.org/10.1128/AEM.71.4.2175-2178.2005.
Xu L, Li H, Vuong C, Vadyvaloo V, Wang J, Yao Y, et al. Role of the luxs quorum-sensing system in biofilm formation and virulence of Staphylococcus epidermidis. Infect Immun. 2005;74(1):488–96. https://doi.org/10.1128/IAI.74.1.488-496.2006.
Mitchell G, Fugère A, Pépin Gaudreau K, Brouillette E, Frost EH, et al. SigB is a dominant regulator of virulence in Staphylococcus aureus small-colony variants. PLoS One. 2013;8(5):e65018. https://doi.org/10.1371/journal.pone.0065018.
Knobloch JK, Bartscht K, Sabottke A, Rohde H, Feucht HH, Mack D. Biofilm formation by Staphylococcus epidermidis depends on functional RsbU, an activator of the sigB operon: differential activation mechanisms due to ethanol and salt stress. J Bacteriol. 2001;183(8):2624–33. https://doi.org/10.1128/JB.183.8.2624-2633.2001.
Otto M. Staphylococcal infections: mechanisms of biofilm maturation and detachment as critical determinants of pathogenicity. Annu Rev Med. 2013;64:175–88.
NIH research on microbial biofilms. Available online: http://grants.nih.gov/grants/guide/pa-files/PA-03-047.html.
Potera C. Forging a link between biofilms and disease. Science. 1999;283:1837–9.
Jamal M, Ahmad W, Andleeb S, Jalil F, Imran M, Nawaz MA, et al. Bacterial biofilm and associated infections. J Chin Med Assoc. 2018;81(1):7–11. https://doi.org/10.1016/j.jcma.2017.07.012.
Hall-Stoodley L, Stoodley P, Kathju S, Høiby N, Moser C, Costerton JW, et al. Towards diagnostic guidelines for biofilm-associated infections. FEMS Immunol Med Microbiol. July 2012;65(2):127–45. https://doi.org/10.1111/j.1574-695X.2012.00968.x.
Del Pozo JL. Biofilm-related disease. Expert Rev Anti-Infect Ther. 2018;16(1):51–65. https://doi.org/10.1080/14787210.2018.1417036.
Dasgupta MK, Larabie M. Biofilms in peritoneal dialysis. Perit Dial Int. 2001;21:S213–7.
Trautner BW, Darouiche RO. Role of biofilm in catheter-associated urinary tract infection. Am J Infect Control. 2004;32(3):177–83. https://doi.org/10.1016/j.ajic.2003.08.005.
Gominet M, Compain F, Beloin C, Lebeaux D. Central venous catheters and biofilms: where do we stand in 2017? APMIS. 2017;125:365–75.
Baddour LM, et al. Infections of cardiovascular implantable electronic devices. N Engl J Med. 2012;367:842–9.
Padera RF. Infection in ventricular assist devices: the role of biofilm. Cardiovasc Pathol. 2006;15(5):264–70. https://doi.org/10.1016/j.carpath.2006.04.008.
Santos APA, Watanabe E, de Andrade D. Biofilm on artificial pacemaker: fiction or reality? Arq Bras Cardiol. 2011;97(5):e113–20. https://doi.org/10.1590/S0066-782X2011001400018.
Piper C, Körfer R, Horstkotte D. Prosthetic valve endocarditis. Heart. 2001;85:590–3.
Zetrenne E, McIntosh BC, McRae MH, Gusberg R, Evans GR, Narayan D. Prosthetic vascular graft infection: a multi-center review of surgical management. Yale J Biol Med. 2007;80(3):113–21.
Geipel U. Pathogenic organisms in hip joint infections. Int J Med Sci. 2009;6(5):234–40. https://doi.org/10.7150/ijms.6.234.
Zimmerli W, Sendi P. Orthopaedic biofilm infections. APMIS. 2017;125:353–64.
Pye AD, Lockhart DEA, Dawson MP, Murray CA, Smith AJ. A review of dental implants and infection. J Hosp Infect. 2009;72(2):104–10. https://doi.org/10.1016/j.jhin.2009.02.010.
Falagas ME, Velakoulis S, Iavazzo C, Athanasiou S. Mesh-related infections after pelvic organ prolapse repair surgery. Eur J Obstet Gynecol Reprod Biol. 2007;134(2):147–56. https://doi.org/10.1016/j.ejogrb.2007.02.024.
Ciorba A, Bovo R, Trevisi P, et al. Eur Arch Otorhinolaryngol. 2012;269:1599. https://doi.org/10.1007/s00405-011-1818-1.
Thissen H, Gengenbach T, du Toit R, Sweeney DF, Kingshott P, Griesser HJ, et al. Clinical observations of biofouling on PEO coated silicone hydrogel contact lenses. Biomaterials. 2010;31(21):5510–9. https://doi.org/10.1016/j.biomaterials.2010.03.040.
Shimizu K, Kobayakawa S, Tsuji A, Tochikubo T. Biofilm formation on hydrophilic intraocular lens material. Curr Eye Res. 2006;31(12):989–97. https://doi.org/10.1080/02713680601038816.
Muench PJ. Infections versus penile implants: the war on bugs. J Urol. 2013;189(5):1631–7. https://doi.org/10.1016/j.juro.2012.05.080.
Ajdic D, Zoghbi Y, Gerth D, Panthaki Z, Thaller S. The relationship of bacterial biofilms and capsular contracture in breast implants. Aesthet Surg J. 2016;36(3):297–309. https://doi.org/10.1093/asj/sjv177.
Edmiston CE Jr, Krepel CJ, Marks RM, Rossi PJ, Sanger J, Goldblatt M, et al. Microbiology of explanted suture segments from infected and noninfected surgical patients. J Clin Microbiol. 2013;51(2):417–21. https://doi.org/10.1128/JCM.02442-12.
Shah SR, Tatara AM, D’Souza RN, Mikos AG, Kasper FK. Evolving strategies for preventing biofilm on implantable materials. Mater Today. 2013;16(5):177–82. https://doi.org/10.1016/j.mattod.2013.05.003.
Mendel V, Simanowski HJ, Scholz HC, et al. Arch Orthop Trauma Surg. 2005;125:363. https://doi.org/10.1007/s00402-004-0774-2.
Tofuku K, Koga H, Yanase M, et al. Eur Spine J. 2012;21:2027. https://doi.org/10.1007/s00586-012-2435-4.
Park MS, Kim YB. Sustained release of antibiotic from a fibrin-gelatin-antibiotic mixture. Laryngoscope. 1997;107:1378–81. https://doi.org/10.1097/00005537-199710000-00016.
Becker PL, Smith RA, Williams RS, Dutkowsky JP. Comparison of antibiotic release from polymethylmethacrylate beads and sponge collagen. J Orthop Res. 1994;12:737–41. https://doi.org/10.1002/jor.1100120517.
Miclau T, Dahners LE, Lindsey RW. In vitro pharmacokinetics of antibiotic release from locally implantable materials. J Orthop Res. 1993;11:627–32. https://doi.org/10.1002/jor.1100110503.
Kent ME, Rapp RP, Smith KM. Antibiotic beads and osteomyelitis: here today, what’s coming tomorrow? Orthopedics. 2006;29:599–603.
Barraud N, Storey MV, Moore ZP, Webb JS, Rice SA, Kjelleberg S. Nitric oxide-mediated dispersal in single- and multi-species biofilms of clinically and industrially relevant microorganisms. Microb Biotechnol. 2009;2:370–8. https://doi.org/10.1111/j.1751-7915.2009.00098.x.
Kolodkin-Gal I, Romero D, Cao S, Clardy J, Kolter R, Losick R. D-amino acids trigger biofilm disassembly. Science. 2010;328(5978):627–9. https://doi.org/10.1126/science.1188628.
Jennings JA, Courtney HS, Haggard WO. Clin Orthop Relat Res. 2012;470:2663. https://doi.org/10.1007/s11999-012-2388-2.
Davies DG, Marques CNH. A fatty acid messenger is responsible for inducing dispersion in microbial biofilms. J Bacteriol. 2009;191(5):1393–403. https://doi.org/10.1128/JB.01214-08.
Hughes K, Sutherland I, Jones M. Microbiology. 144(11):3039–47. https://doi.org/10.1099/00221287-144-11-3039.
Lu TK, Collins JJ. Dispersing biofilms with engineered enzymatic bacteriophage. Proc Natl Acad Sci. 2007;104(27):11197–202. https://doi.org/10.1073/pnas.0704624104.
Desai NP, Hubbell JA. Surface physical interpenetrating networks of poly(ethylene terephthalate) and poly(ethylene oxide) with biomedical applications. Macromolecules. 1992;25(1):226–32. https://doi.org/10.1021/ma00027a038.
Desai NP, Hubbell JA. Solution technique to incorporate polyethylene oxide and other water-soluble polymers into surfaces of polymeric biomaterials. Biomaterials. 1991;12(2):144–53. https://doi.org/10.1016/0142-9612(91)90193-E.
Lowenberg BF, Pilliar RM, Aubin JE, Sodek J, Melcher AH. Cell attachment of human gingival fibpoblasts in vitro to porous-surfaced titanium alloy discs coated with collagen and platelet-derived growth factor. Biomaterials. 1988;9(4):302–9. https://doi.org/10.1016/0142-9612(88)90023-3.
Schakenraad JM, Arends J, Busscher HJ, Dijk F, van Wachem PB, Wildevuur CRH. Kinetics of cell spreading on protein precoated substrata: a study of interfacial aspects. Biomaterials. 1989;10(1):43–50. https://doi.org/10.1016/0142-9612(89)90008-2.
Gun J, Sagiv J. On the formation and structure of self-assembling monolayers: III. Time of formation, solvent retention, and release. J Colloid Interface Sci. 1986;112(2):457–72. https://doi.org/10.1016/0021-9797(86)90114-1.
Ulman A. Formation and structure of self-assembled monolayers. Chem Rev. 1996;96(4):1533–54. https://doi.org/10.1021/cr9502357.
Senaratne W, Andruzzi L, Ober CK. Self-assembled monolayers and polymer brushes in biotechnology: current applications and future perspectives. Biomacromolecules. 2005;6(5):2427–48. https://doi.org/10.1021/bm050180a.
Rauf S, Zhou D, Abell C, Klenermanb D, Kang D-J. Building three-dimensional nanostructures with active enzymes by surface templated layer-by-layer assembly. https://doi.org/10.1039/b517557g.
Quinn JF, Johnston APR, Such GK, Zelikina AN, Caruso F. Next generation, sequentially assembled ultrathin films: beyond electrostatics. https://doi.org/10.1039/B610778H.
Such GK, Johnston APR, Caruso F. Engineered hydrogen-bonded polymer multilayers: from assembly to biomedical applications. https://doi.org/10.1039/C0CS00001A.
Davila J, Harriman A. Photosensitized oxidation of biomaterials and related model compounds. Photochem Photobiol. 1989;50:29–35. https://doi.org/10.1111/j.1751-1097.1989.tb04126.x.
Gabriel M, van Nieuw Amerongen GP, van Hinsbergh VWM, van Nieuw Amerongen AV, Zentner A. Direct grafting of RGD-motif-containing peptide on the surface of polycaprolactone films. J Biomater Sci Polym Ed. 2006;17(5):567–77. https://doi.org/10.1163/156856206776986288.
Park GE, Pattison MA, Park K, Webster TJ. Accelerated chondrocyte functions on NaOH-treated PLGA scaffolds. Biomaterials. 2005;26(16):3075–82. https://doi.org/10.1016/j.biomaterials.2004.08.005.
Nam YS, Yoon JJ, Lee JG, Park TG. Adhesion behaviours of hepatocytes cultured onto biodegradable polymer surface modified by alkali hydrolysis process. J Biomater Sci Polym Ed. 1999;10(11):1145–58. https://doi.org/10.1163/156856299X00801.
Ratner BD. Characterization of graft polymers for biomedical applications. J Biomed Mater Res. 1980;14:665–87. https://doi.org/10.1002/jbm.820140512.
Ruckenstein E, Li ZF. Surface modification and functionalization through the self-assembled monolayer and graft polymerization. Adv Colloid Interf Sci. 2005;113(1):43–63. https://doi.org/10.1016/j.cis.2004.07.009.
Ratner BD. Plasma deposition for biomedical applications: a brief review. J Biomater Sci Polym Ed. 1993;4(1):3–11. https://doi.org/10.1163/156856292X00240.
Nitschke M. Plasma modification of polymer surfaces and plasma polymerization. In: Stamm M, editor. Polymer surfaces and interfaces. Berlin, Heidelberg: Springer; 2008.
Hume EBH, Baveja J, Muir B, Schubert TL, Kumar N, Kjelleberg S, et al. The control of Staphylococcus epidermidis biofilm formation and in vivo infection rates by covalently bound furanones. Biomaterials. 2004;25(20):5023–30. https://doi.org/10.1016/j.biomaterials.2004.01.048.
Barrios CA, Xu Q, Cutright T, Newby B-m Z. Incorporating zosteric acid into silicone coatings to achieve its slow release while reducing fresh water bacterial attachment. Colloids Surf B: Biointerfaces. 2005;41(2–3):83–93. https://doi.org/10.1016/j.colsurfb.2004.09.009.
Dell’orto S, Cattò C, Villa F, Forlani F, Vassallo E, Morra M, et al. Low density polyethylene functionalized with antibiofilm compounds inhibits Escherichia coli cell adhesion. J Biomed Mater Res A. 2017;2017(105A):3251–61.
Nowatzki PJ, Koepsel RR, Stoodley P, Min K, Harper A, Murata H, et al. Salicylic acid-releasing polyurethane acrylate polymers as anti-biofilm urological catheter coatings. Acta Biomater. 2012;8(5):1869–80. https://doi.org/10.1016/j.actbio.2012.01.032.
Norcy TL, Niemann H, Proksch P, Linossier I, Vallée-Réhel K, Hellio C, et al. Anti-biofilm effect of biodegradable coatings based on hemibastadin derivative in marine environment. Int J Mol Sci. 2017;18(7):1520. https://doi.org/10.3390/ijms18071520.
Cattò C, James G, Villa F, Villa S, Cappitelli F. Zosteric acid and salicylic acid bound to a low density polyethylene surface successfully control bacterial biofilm formation. Biofouling. 2018;34(4):440–52. https://doi.org/10.1080/08927014.2018.1462342.
Zhao C, Deng B, Chen G, et al. Nano Res. 2016;9:963. https://doi.org/10.1007/s12274-016-0984-2.
Su XJ, Zhao Q, Wang S, Bendavid A. Modification of diamond-like carbon coatings with fluorine to reduce biofouling adhesion. Surf Coat Technol. 2010;204(15):2454–8. https://doi.org/10.1016/j.surfcoat.2010.01.022.
Kang S, Herzberg M, Rodrigues DF, Elimelech M. Antibacterial effects of carbon nanotubes: size does matter! Langmuir. 2008;24(13):6409–13. https://doi.org/10.1021/la800951v.
Ma J, Sun Y, Gleichauf K, Lou J, Langmuir QL. Nanostructure on taro leaves resists fouling by colloids and bacteria under submerged conditions. 2011;27(16):10035–40. https://doi.org/10.1021/la2010024.
Cheng YT, Rodak DE, Wong CA, Hayden CA. Effects of micro- and nano-structures on the self-cleaning behaviour of lotus leaves. Nanotechnology. 2006;17:1359–62.
Watson GS, Green DW, Lin S, Li X, Cribb BW, Myhra S, et al. A gecko skin micro/nano structure – a low adhesion, superhydrophobic, anti-wetting, self-cleaning, biocompatible, antibacterial surface. Acta Biomater. 2015;21:109–22. https://doi.org/10.1016/j.actbio.2015.03.007.
Wen L, Weaver JC, Lauder GV. Biomimetic shark skin: design, fabrication and hydrodynamic function. J Exp Biol. 2014;217:1656–66. https://doi.org/10.1242/jeb.097097.
Hasan J, Webb HK, Truong VK, et al. Appl Microbiol Biotechnol. 2013;97:9257. https://doi.org/10.1007/s00253-012-4628-5.
Kelleher SM, Habimana O, Lawler J, O’Reilly B, Daniels S, Casey E, et al. Cicada wing surface topography: an investigation into the bactericidal properties of nanostructural features. ACS Appl Mater Interfaces. 2016;8(24):14966–74. https://doi.org/10.1021/acsami.5b08309.
Bixler GD, Bhushan B. Fluid drag reduction and efficient self-cleaning with rice leaf and butterfly wing bioinspired surfaces. Nanoscale. 2013;5:7685. https://doi.org/10.1039/C3NR01710A.
Ivanova EP, et al. Bactericidal activity of black silicon. Nat Commun. 2013;4:2838. https://doi.org/10.1038/ncomms3838.
Szewczyk PK, Knapczyk-Korczak J, Ura DP, Metwally S, Gruszczyński A, Stachewicz U. Biomimicking wetting properties of spider web from Linothele megatheloides with electrospun fibers. Mater Lett. 2018. https://doi.org/10.1016/j.matlet.2018.09.007.
Acikgoz C, Hempenius MA, Huskens J, Vancso GJ. Polymers in conventional and alternative lithography for the fabrication of nanostructures. Eur Polym J. 2011;47(11):2033–52. https://doi.org/10.1016/j.eurpolymj.2011.07.025.
Zhang G, Wang D. Colloidal lithography—the art of nanochemical patterning. Chem Asian J. 2009;4:236–45. https://doi.org/10.1002/asia.200800298.
Wood MA. Colloidal lithography and current fabrication techniques producing in-plane nanotopography for biological applications. J R Soc Interface. 2007;4:1–17. https://doi.org/10.1098/rsif.2006.0149.
Wang Y, Zhang M, Lai Y, Chi L. Advanced colloidal lithography: from patterning to applications. Nano Today. 2018;22:36–61. https://doi.org/10.1016/j.nantod.2018.08.010.
Puliyalil H, Cvelbar U. Selective plasma etching of polymeric substrates for advanced applications. Nanomaterials. 2016;6(6):108. https://doi.org/10.3390/nano6060108.
Vasilev K, Griesser SS, Griesser HJ. Antibacterial surfaces and coatings produced by plasma techniques. Plasma Process Polym. 2011;8:1010–23. https://doi.org/10.1002/ppap.201100097.
Joseph Nathanael A, Han SS, Oh TH. Polymer-assisted hydrothermal synthesis of hierarchically arranged hydroxyapatite nanoceramic. J Nanomater. 2013;2013:962026, 8 pages. https://doi.org/10.1155/2013/962026.
Tsimbouri PM, et al. Osteogenic and bactericidal surfaces from hydrothermal titanium nanowires on titanium substrates. Sci Rep. 2016;6:36857. https://doi.org/10.1038/srep36857.
Qing D, Wei D, Liu S, Cheng S, Hu N, Wang Y, et al. The hydrothermal treated Zn-incorporated titania based microarc oxidation coating: surface characteristics, apatite-inducing ability and antibacterial ability. Surf Coat Technol. 2018;352:489–500. https://doi.org/10.1016/j.surfcoat.2018.08.007.
García LEG, MacGregor MN, Visalakshan RM, Ninan N, Cavallaro AA, Trinidad AD, et al. Self-sterilizing antibacterial silver-loaded microneedles. Chem Commun. 2019;55:171. https://doi.org/10.1039/C8CC06035E.
Mücklich F, Lasagni A, Daniel C. Laser interference metallurgy – using interference as a tool for micro/nano structuring. Int J Mater Res. 2006;97(10):1337–44. https://doi.org/10.3139/146.101375.
Lasagni A, D’Alessandria M, Giovanelli R, Mücklich F. Advanced design of periodical architectures in bulk metals by means of laser interference metallurgy. Appl Surf Sci. 2007;254(4):930–6. https://doi.org/10.1016/j.apsusc.2007.08.010.
Chi GJ, Yao SW, Fan J, Zhang WG, Wang HZ. Antibacterial activity of anodized aluminum with deposited silver. Surf Coat Technol. 2002;157(2–3):162–5. https://doi.org/10.1016/S0257-8972(02)00150-0.
Gilani S, Ghorbanpour M, Parchehbaf Jadid A. J Nanostruct Chem. 2016;6:183. https://doi.org/10.1007/s40097-016-0194-1.
Zhao D-Y, Huang Z-P, Wang M-J, Wang T, Jin Y. Vacuum casting replication of micro-riblets on shark skin for drag-reducing applications. J Mater Process Technol. 2012;212(1):198–202. https://doi.org/10.1016/j.jmatprotec.2011.09.002.
Diu T, Faruqui N, Sjöström T, Lamarre B, Jenkinson HF, Su B, et al. Cicada-inspired cell-instructive nanopatterned arrays. Sci Rep. 2014;4:7122. https://doi.org/10.1038/srep07122.
Hizal F, Zhuk I, Sukhishvili S, Busscher HJ, Van Der Mei HC, Choi CH. Impact of 3D hierarchical nanostructures on the antibacterial efficacy of a bacteria-triggered self-defensive antibiotic coating. ACS Appl Mater Interfaces. 2015;7:20304–13. https://doi.org/10.1021/acsami.5b05947.
Bhadra CM, Khanh Truong V, Pham VTH, Al Kobaisi M, Seniutinas G, Wang JY, et al. Antibacterial titanium nano-patterned arrays inspired by dragonfly wings. Sci Rep. 2015;5:16817. https://doi.org/10.1038/srep16817.
Fisher LE, Yang Y, Yuen M-F, Zhang W, Nobbs AH, Su B. Bactericidal activity of biomimetic diamond nanocone surfaces. Biointerphases. 2016;11:11014. https://doi.org/10.1116/1.4944062.
Hasan J, Raj S, Yadav L, Chatterjee K. Engineering a nanostructured “super surface” with superhydrophobic and superkilling properties. RSC Adv. 2015;5:44953–9. https://doi.org/10.1039/C5RA05206H.
Dickson MN, Liang EI, Rodriguez LA, Vollereaux N, Yee AF. Nanopatterned polymer surfaces with bactericidal properties. Biointerphases. 2015;10:21010. https://doi.org/10.1116/1.4922157.
Valle J, Burgui S, Langheinrich D, Gil C, Solano C, Toledo-Arana A, et al. Evaluation of surface microtopography engineered by direct laser interference for bacterial antibiofouling. Macromol Biosci. 2015;15:1060–9. https://doi.org/10.1002/mabi.201500107.
Wu S, Zuber F, Brugger J, Maniura-Weber K, Ren Q. Antibacterial Au nanostructured surfaces. Nanoscale. 2016:2620–5. https://doi.org/10.1039/C5NR06157A.
Moore B, Asadi E, Lewis G. Deposition methods for microstructured and nanostructured coatings on metallic bone implants: a review. Adv Mater Sci Eng. 2017;2017:5812907, 9 pages. https://doi.org/10.1155/2017/5812907.
Bakhshandeh S, Yavari SA. Electrophoretic deposition: a versatile tool against biomaterial associated infections. J Mater Chem B. 2018;6:1128. https://doi.org/10.1039/C7TB02445B.
Amiri S, Rahimi A. Iran Polym J. 2016;25:559. https://doi.org/10.1007/s13726-016-0440-x.
Champagne VK, Helfritch DJ. A demonstration of the antimicrobial effectiveness of various copper surfaces. J Biol Eng. 2013;7(1):8. https://doi.org/10.1186/1754-1611-7-8.
Antimicrobial activity of metals: mechanisms, molecular targets and applications. Nat Rev Microbiol. 2013;11:371–84. https://doi.org/10.1038/nrmicro3028.
Phillips DJ, Harrison J, Richards SJ, Mitchell DE, Tichauer E, Hubbard A, et al. Evaluation of the antimicrobial activity of cationic polymers against mycobacteria: toward antitubercular macromolecules. Biomacromolecules. 2017;18(5):1592–9. https://doi.org/10.1021/acs.biomac.7b00210.
Carmona-Ribeiro AM, De Melo Carrasco LD. Cationic antimicrobial polymers and their assemblies. Int J Mol Sci. 2013;14(5):9906–46.
Baier G, Cavallaro A, Friedemann K, Müller B, Glasser G, Vasilev K, et al. Enzymatic degradation of poly(l-lactide) nanoparticles followed by the release of octenidine and their bactericidal effects. Nanomedicine. 2014;10(1):131–9. https://doi.org/10.1016/j.nano.2013.07.002.
Zhao L, Chu PK, Zhang Y, Wu Z. Antibacterial coatings on titanium implants. J Biomed Mater Res. 2009;91B:470–80. https://doi.org/10.1002/jbm.b.31463.
Kong M, Chen XG, Xing K, Park HJ. Antimicrobial properties of chitosan and mode of action: a state of the art review. Int J Food Microbiol. 2010;144(1):51–63. https://doi.org/10.1016/j.ijfoodmicro.2010.09.012.
Bahar AA, Ren D. Antimicrobial peptides. Pharmaceuticals. 2013;6(12):1543–75. https://doi.org/10.3390/ph6121543.
Mahlapuu M, Håkansson J, Ringstad L, Björn C. Antimicrobial peptides: an emerging category of therapeutic agents. Front Cell Infect Microbiol. 2016;6:194. https://doi.org/10.3389/fcimb.2016.00194.
Riool M, de Breij A, Drijfhout JW, Nibbering PH, Zaat S. Antimicrobial peptides in biomedical device manufacturing. Front Chem. 2017;5:63. https://doi.org/10.3389/fchem.2017.00063.
Zilberman M, Elsner JJ. Antibiotic-eluting medical devices for various applications. J Control Release. 2008;130(3):202–15. https://doi.org/10.1016/j.jconrel.2008.05.020.
Algburi A, Comito N, Kashtanov D, Dicks LMT, Chikindas ML. Appl Environ Microbiol. 2017;83(3):e02508–16. https://doi.org/10.1128/AEM.02508-16.
Ciofu O, Rojo-Molinero E, Macià MD, Oliver A. Antibiotic treatment of biofilm infections. APMIS. 2017;125:304–19.
Graham MV, Cady NC. Nano and microscale topographies for the prevention of bacterial surface fouling. Coatings. 2014;4(1):37–59. https://doi.org/10.3390/coatings4010037.
Reza Nejadnik M, van der Mei HC, Norde W, Busscher HJ. Bacterial adhesion and growth on a polymer brush-coating. Biomaterials. 2008;29(30):4117–21. https://doi.org/10.1016/j.biomaterials.2008.07.014.
Muszanska AK, Rochford ETJ, Gruszka A, Bastian AA, Busscher HJ, Norde W, et al. Antiadhesive polymer brush coating functionalized with antimicrobial and rgd peptides to reduce biofilm formation and enhance tissue integration. Biomacromolecules. 2014;15(6):2019–26. https://doi.org/10.1021/bm500168s.
Li X, Wu B, Chen H, Nan K, Jin Y, Sun L, et al. Recent developments in smart antibacterial surfaces to inhibit biofilm formation and bacterial infections. J Mater Chem B. 2018;6:4274. https://doi.org/10.1039/C8TB01245H.
Cheng G, Zhang Z, Chen S, Bryers JD, Jiang S. Inhibition of bacterial adhesion and biofilm formation on zwitterionic surfaces. Biomaterials. 2007;28(29):4192–9. https://doi.org/10.1016/j.biomaterials.2007.05.041.
Schlenoff JB. Zwitteration: coating surfaces with zwitterionic functionality to reduce nonspecific adsorption. Langmuir. 2014;30(32):9625–36. https://doi.org/10.1021/la500057j.
Brackman G, Cos P, Maes L, Nelis HJ, Coenye T. Quorum sensing inhibitors increase the susceptibility of bacterial biofilms to antibiotics in vitro and in vivo. Antimicrob Agents Chemother. 2011;55(6):2655–61. https://doi.org/10.1128/AAC.00045-11.
Bhardwaj AK, Vinothkumar K, Rajpara N. Bacterial quorum sensing inhibitors: attractive alternatives for control of infectious pathogens showing multiple drug resistance. Recent Pat Antiinfect Drug Discov. 2013;8:68. https://doi.org/10.2174/1574891X11308010012.
Brackman G, Coenye T. Quorum sensing inhibitors as anti-biofilm agents. Curr Pharm Des. 2015;21:5. https://doi.org/10.2174/1381612820666140905114627.
Jiang Q, Chen J, Yang C, Yin Y, Yao K. Quorum sensing: a prospective therapeutic target for bacterial diseases. Biomed Res Int. 2019;2019:2015978. https://doi.org/10.1155/2019/2015978.
Singh BN, Prateeksha, Upreti DK, Singh BR, Defoirdt T, Gupta VK, et al. Bactericidal, quorum quenching and anti-biofilm nanofactories: a new niche for nanotechnologists. Crit Rev Biotechnol. 2017;37(4):525–40. https://doi.org/10.1080/07388551.2016.1199010.
Howlin RP, Cathie K, Hall-Stoodley L, Cornelius V, Duignan C, Allan RN, et al. Low-dose nitric oxide as targeted anti-biofilm adjunctive therapy to treat chronic Pseudomonas aeruginosa infection in cystic fibrosis. Mol Ther. 2017;25(9):2104–16. https://doi.org/10.1016/j.ymthe.2017.06.021.
Sadrearhami Z, Nguyen T, Namivandi-Zangeneh R, Jung K, Wong EHH, Boyer C. Recent advances in nitric oxide delivery for antimicrobial applications using polymer-based systems. J Mater Chem B. 2018;6:2945. https://doi.org/10.1039/C8TB00299A.
Zhu W, Wang Y, Li K, Gao J, Huang CH, Chen CC, et al. Antibacterial drug leads: DNA and enzyme multitargeting. J Med Chem. 2015;58(3):1215–27. https://doi.org/10.1021/jm501449u.
Pavlukhina SV, Kaplan JB, Xu L, Chang W, Yu X, Madhyastha S, et al. Noneluting Enzymatic Antibiofilm Coatings. ACS Appl Mater Interfaces. 2012;4(9):4708–16. https://doi.org/10.1021/am3010847.
Chung PY, Toh YS. Anti-biofilm agents: recent breakthrough against multi-drug resistant Staphylococcus aureus. Pathog Dis. 2014;70(3):231–9. https://doi.org/10.1111/2049-632X.12141.
Khatoon Z, McTiernan CD, Suuronen EJ, Mah TF, Alarcon EI. Bacterial biofilm formation on implantable devices and approaches to its treatment and prevention. Heliyon. 2018;4(12):e01067. https://doi.org/10.1016/j.heliyon.2018.e01067.
Gambino M, Cappitelli F. Mini-review: biofilm responses to oxidative stress. Biofouling. 2016;32(2):167–78. https://doi.org/10.1080/08927014.2015.1134515.
Hope CK, Wilson M. Induction of lethal photosensitization in biofilms using a confocal scanning laser as the excitation source. J Antimicrob Chemother. 2006;57(6):1227–30. https://doi.org/10.1093/jac/dkl096.
de Melo WC, Avci P, de Oliveira MN, Gupta A, Vecchio D, Sadasivam M, et al. Photodynamic inactivation of biofilm: taking a lightly colored approach to stubborn infection. Expert Rev Anti-Infect Ther. 2013;11(7):669–93. https://doi.org/10.1586/14787210.2013.811861.
Shrestha A, et al. Antibiofilm efficacy of photosensitizer-functionalized bioactive nanoparticles on multispecies biofilm. J Endod. 40(10):1604–10. https://doi.org/10.1016/j.joen.2014.03.009.
Castillo-Martínez JC, Martínez-Castañón GA, Martínez-Gutierrez F, et al. Antibacterial and antibiofilm activities of the photothermal therapy using gold nanorods against seven different bacterial strains. J Nanomater. 2015;2015:783671, 7 pages. https://doi.org/10.1155/2015/783671.
Teng CP, Zhou T, Ye E, Liu S, Koh LD, Low M, et al. Effective targeted photothermal ablation of multidrug resistant bacteria and their biofilms with NIR-absorbing gold nanocrosses. Adv Healthc Mater. 2016;5:2122–30. https://doi.org/10.1002/adhm.201600346.
Jia X, Ahmad I, Yang R, Wang C. Versatile graphene-based photothermal nanocomposites for effectively capturing and killing bacteria, and for destroying bacterial biofilms. J Mater Chem B. 2017;5:2459. https://doi.org/10.1039/C6TB03084J.
Pourhajibagher M, Chiniforush N, Ghorbanzadeh R, Bahador A. Photo-activated disinfection based on indocyanine green against cell viability and biofilm formation of Porphyromonas gingivalis. Photodiagn Photodyn Ther. 2017;17:61–4. https://doi.org/10.1016/j.pdpdt.2016.10.003.
Park KD, Kim YS, Han DK, Kim YH, Lee EHB, Suh H, et al. Bacterial adhesion on PEG modified polyurethane surfaces. Biomaterials. 1998;19(7–9):851–9. https://doi.org/10.1016/S0142-9612(97)00245-7.
Roosjen A, Kaper HJ, van der Mei HC, Norde W, Busscher HJ. Inhibition of adhesion of yeasts and bacteria by poly(ethylene oxide)-brushes on glass in a parallel plate flow chamber. Microbiology. 2003;149(Pt 11):3239e46. https://doi.org/10.1099/mic.0.26519-0.
Hendricks SK, Kwok C, Shen M, Horbett TA, Ratner BD, Bryers JD. Plasma-deposited membranes for controlled release of antibiotic to prevent bacterial adhesion and biofilm formation. J Biomed Mater Res. 2000;50:160–70. https://doi.org/10.1002/(SICI)1097-4636(200005)50:2<160::AID-JBM10>3.0.CO;2-M.
Lalani R, Liu L. Electrospun zwitterionic poly(sulfobetaine methacrylate) for nonadherent, superabsorbent, and antimicrobial wound dressing applications. Biomacromolecules. 2012;13(6):1853–63. https://doi.org/10.1021/bm300345e.
Zhang F, Zhang Z, Zhu X, Kang E-T, Neoh K-G. Silk-functionalized titanium surfaces for enhancing osteoblast functions and reducing bacterial adhesion. Biomaterials. 2008;29(36):4751–9. https://doi.org/10.1016/j.biomaterials.2008.08.043.
Webster TJ, Patel AA, Rahaman MN, Sonny Bal B. Anti-infective and osteointegration properties of silicon nitride, poly(ether ether ketone), and titanium implants. Acta Biomater. 2012;8(12):4447–54. https://doi.org/10.1016/j.actbio.2012.07.038.
Ma Y, Chen M, Jones JE, Ritts AC, Yu Q, Sun H. Inhibition of Staphylococcus epidermidis biofilm by trimethylsilane plasma coating. Antimicrob Agents Chemother. 2012;56(11):5923–37. https://doi.org/10.1128/AAC.01739-1.
Berry JA, Biedlingmaier JF, Whelan PJ. In vitro resistance to bacterial biofilm formation on coated fluoroplastic tympanostomy tubes. Otolaryngol Head Neck Surg. 2000;123(3):246–51. https://doi.org/10.1067/mhn.2000.107458.
Kenan DJ, Walsh EB, Meyers SR, O’Toole GA, Carruthers EG, Lee WK, et al. Peptide-PEG amphiphiles as cytophobic coatings for mammalian and bacterial cells. Chem Biol. 2006;13(7):695–700. https://doi.org/10.1016/j.chembiol.2006.06.013.
Stallard CP, McDonnell KA, Onayemi OD, O’Gara JP, Dowling DP. Evaluation of protein adsorption on atmospheric plasma deposited coatings exhibiting superhydrophilic to superhydrophobic properties. Biointerphases. 2012;7:31. https://doi.org/10.1007/s13758-012-0031-0.
Tebbs SE, Elliott TSJ. Eur J Clin Microbiol Infect Dis. 1994;13:111. https://doi.org/10.1007/BF01982182.
Popelka A, Novák I, Lehocký M, Chodák I, Sedliačik J, Gajtanska M, et al. Anti-bacterial treatment of polyethylene by cold plasma for medical purposes. Molecules. 2012;17:762–85.
Rothenburger S, Spangler D, Bhende S, Burkley D. In vitro antimicrobial evaluation of coated VICRYL* plus antibacterial suture (coated polyglactin 910 with triclosan) using zone of inhibition assays. Surg Infect. 2002;3(s1):s79–87. https://doi.org/10.1089/sur.2002.3.s1-79.
Cao Z, Sun Y. N-halamine-based chitosan: preparation, characterization, and antimicrobial function. J Biomed Mater Res. 2008;85A:99–107. https://doi.org/10.1002/jbm.a.31463.
Martin TP, Kooi SE, Chang SH, Sedransk KL, Gleason KK. Initiated chemical vapor deposition of antimicrobial polymer coatings. Biomaterials. 2007;28(6):909–15. https://doi.org/10.1016/j.biomaterials.2006.10.009.
Luo J, Sun Y. Acyclic N-halamine-based biocidal tubing: preparation, characterization, and rechargeable biofilm-controlling functions. J Biomed Mater Res. 2008;84A:631–42. https://doi.org/10.1002/jbm.a.31301.
Cen L, Neoh KG, Kang ET. Antibacterial activity of cloth functionalized with N-alkylated poly(4-vinylpyridine). J Biomed Mater Res. 2004;71A:70–80. https://doi.org/10.1002/jbm.a.30125.
Kevin B, Liang J, Wu R, Worley SD, Lee J, Broughton RM, et al. Huang, synthesis and antimicrobial applications of 5,5′-ethylenebis[5-methyl-3-(3-triethoxysilylpropyl)hydantoin]. Biomaterials. 2006;27(27):4825–30. https://doi.org/10.1016/j.biomaterials.2006.05.023.
Tiller JC, Lee SB, Lewis K, Klibanov AM. Polymer surfaces derivatized with poly(vinyl-N-hexylpyridinium) kill airborne and waterborne bacteria. Biotechnol Bioeng. 2002;79:465–71. https://doi.org/10.1002/bit.10299.
Lin J, Qiu S, Lewis K, Klibanov AM. Mechanism of bactericidal and fungicidal activities of textiles covalently modified with alkylated polyethylenimine. Biotechnol Bioeng. 2003;83:168–72. https://doi.org/10.1002/bit.10651.
Liang J, Chen Y, Barnes K, Wu R, Worley SD, Huang T-S. N-halamine/quat siloxane copolymers for use in biocidal coatings. Biomaterials. 2006;27(11):2495–501. https://doi.org/10.1016/j.biomaterials.2005.11.020.
Pfeufer NY, Hofmann-Peiker K, Mühle M, et al. Bioactive coating of titanium surfaces with recombinant human β-defensin-2 (rHuβD2) may prevent bacterial colonization in orthopaedic surgery. J Bone Joint Surg Am. 2011;93(9):840e6. https://doi.org/10.2106/JBJS.I.01738.
Hilpert K, Elliott M, Jenssen H, Kindrachuk J, Fjell CD, Körner J, et al. Screening and characterization of surface-tethered cationic peptides for antimicrobial activity. Chem Biol. 2009;16(1):58–69. https://doi.org/10.1016/j.chembiol.2008.11.006.
Li Y, Kumar KN, Dabkowski JM, Corrigan M, Scott RW, Nüsslein K, et al. New bactericidal surgical suture coating. Langmuir. 2012;28(33):12134–9. https://doi.org/10.1021/la302732w.
Willcox M, Hume E, Aliwarga Y, Kumar N, Cole N. A novel cationic-peptide coating for the prevention of microbial colonization on contact lenses. J Appl Microbiol. 2008;105:1817–25. https://doi.org/10.1111/j.1365-2672.2008.03942.x.
Jing FJ, Huang N, Liu YW, Zhang W, Zhao XB, Fu RK, et al. Hemocompatibility and antibacterial properties of lanthanum oxide films synthesized by dual plasma deposition. J Biomed Mater Res. 2008;87A:1027–33. https://doi.org/10.1002/jbm.a.31838.
Qu J, Lu X, Li D, Ding Y, Leng Y, Weng J, et al. Silver/hydroxyapatite composite coatings on porous titanium surfaces by sol-gel method. J Biomed Mater Res. 2011;97B:40–8. https://doi.org/10.1002/jbm.b.31784.
Heidenau F, Mittelmeier W, Detsch R, et al. J Mater Sci Mater Med. 2005;16:883. https://doi.org/10.1007/s10856-005-4422-3.
Shameli K, Ahmad MB, Zargar M, Yunus WM, Ibrahim NA. Fabrication of silver nanoparticles doped in the zeolite framework and antibacterial activity. Int J Nanomedicine. 2011;6:331–41. https://doi.org/10.2147/IJN.S16964.
Zhang Y, Zhong S, Zhang M, et al. J Mater Sci. 2009;44:457. https://doi.org/10.1007/s10853-008-3129-5.
Jeon H-J, Yi S-C, Seong-Geun O. Preparation and antibacterial effects of Ag–SiO2 thin films by sol–gel method. Biomaterials. 2003;24(27):4921–8. https://doi.org/10.1016/S0142-9612(03)00415-0.
Colon G, Ward BC, Webster TJ. Increased osteoblast and decreased Staphylococcus epidermidis functions on nanophase ZnO and TiO2. J Biomed Mater Res. 2006;78A:595–604. https://doi.org/10.1002/jbm.a.30789.
Jia H, Hou W, Wei L, Xu B, Liu X. The structures and antibacterial properties of nano-SiO2 supported silver/zinc–silver materials. Dent Mater. 2008;24(2):244–9. https://doi.org/10.1016/j.dental.2007.04.015.
Hu H, Zhang W, Qiao Y, Jiang X, Liu X, Ding C. Antibacterial activity and increased bone marrow stem cell functions of Zn-incorporated TiO2 coatings on titanium. Acta Biomater. 2012;8(2):904–15. https://doi.org/10.1016/j.actbio.2011.09.031.
Applerot G, Abu-Mukh R, Irzh A, Charmet J, Keppner H, Laux E, et al. Decorating parylene-coated glass with ZnO nanoparticles for antibacterial applications: a comparative study of sonochemical, microwave, and microwave-plasma coating routes. ACS Appl Mater Interfaces. 2010;2(4):1052–9. https://doi.org/10.1021/am900825h.
Lellouche J, Kahana E, Elias S, Gedanken A, Banin E. Antibiofilm activity of nanosized magnesium fluoride. Biomaterials. 2009;30(30):5969–78. https://doi.org/10.1016/j.biomaterials.2009.07.037.
Jansson T, Clare-Salzler ZJ, Zaveri TD, Mehta S, Dolgova NV, Chu BH, et al. Antibacterial effects of zinc oxide nanorod surfaces. J Nanosci Nanotechnol. 2012;12(9):7132e8. https://doi.org/10.1166/jnn.2012.6587.
Juan L, Zhimin Z, Anchun M, Lei L, Jingchao Z. Deposition of silver nanoparticles on titanium surface for antibacterial effect. Int J Nanomedicine. 2010;5:261–7. https://doi.org/10.2147/IJN.S63807.
Grandi S, Cassinelli V, Bini M, Saino E, Mustarelli P, Arciola CR, et al. Bone reconstruction: Au nanocomposite bioglasses with antibacterial properties. Int J Artif Organs. 2011;34(9):920–8. https://doi.org/10.5301/ijao.5000059.
Sotiriou GA, Pratsinis SE. Antibacterial activity of nanosilver ions and particles. Environ Sci Technol. 2010;44(14):5649–54. https://doi.org/10.1021/es101072s.
Hetrick EM, Shin JH, Stasko NA, Johnson CB, Wespe DA, Holmuhamedov E, et al. Bactericidal efficacy of nitric oxide-releasing silica nanoparticles. ACS Nano. 2008;2(2):235–46. https://doi.org/10.1021/nn700191f.
Riccio DA, Dobmeier KP, Hetrick EM, Privett BJ, Paul HS, Schoenfisch MH. Nitric oxide-releasing S-nitrosothiol-modified xerogels. Biomaterials. 2009;30(27):4494–502. https://doi.org/10.1016/j.biomaterials.2009.05.006.
Fox S, Wilkinson TS, Wheatley PS, Xiao B, Morris RE, Sutherland A, et al. NO-loaded Zn2+-exchanged zeolite materials: a potential bifunctional anti-bacterial strategy. Acta Biomater. 2010;6(4):1515–21. https://doi.org/10.1016/j.actbio.2009.10.038.
Nablo BJ, Prichard HL, Butler RD, Klitzman B, Schoenfisch MH. Inhibition of implant-associated infections via nitric oxide release. Biomaterials. 2005;26(34):6984–90. https://doi.org/10.1016/j.biomaterials.2005.05.017.
Dunnill CW, Parkin IP. Nitrogen-doped TiO2 thin films: photocatalytic applications for healthcare environments. Dalton Trans. 2011;40:1635. https://doi.org/10.1039/C0DT00494D.
Pratap Reddy M, Venugopal A, Subrahmanyam M. Hydroxyapatite-supported Ag–TiO2 as Escherichia coli disinfection photocatalyst. Water Res. 2007;41(2):379–86. https://doi.org/10.1016/j.watres.2006.09.018.
Zhou G, Li Y, Xiao W, Zhang L, Zuo Y, Xue J, et al. Synthesis, characterization, and antibacterial activities of a novel nanohydroxyapatite/zinc oxide complex. J Biomed Mater Res. 2008;85A:929–37. https://doi.org/10.1002/jbm.a.31527.
Nakamura K, Yamada Y, Ikai H, Kanno T, Sasaki K, Niwano Y. Bactericidal action of photoirradiated gallic acid via reactive oxygen species formation. J Agric Food Chem. 2012;60(40):10048–54. https://doi.org/10.1021/jf303177p.
Tsuang Y, Sun J, Huang Y, Lu C, Chang WH, Wang C. Studies of photokilling of bacteria using titanium dioxide nanoparticles. Artif Organs. 2008;32:167–74. https://doi.org/10.1111/j.1525-1594.2007.00530.x.
Perni S, Piccirillo C, Pratten J, Prokopovich P, Chrzanowski W, Parkin IP, et al. The antimicrobial properties of light-activated polymers containing methylene blue and gold nanoparticles. Biomaterials. 2009;30(1):89–93. https://doi.org/10.1016/j.biomaterials.2008.09.020.
Fu G, Vary PS, Lin C-T. Anatase TiO2 nanocomposites for antimicrobial coatings. J Phys Chem B. 2005;109(18):8889–98. https://doi.org/10.1021/jp0502196.
Sunkara BK, Misra RDK. Enhanced antibactericidal function of W4+-doped titania-coated nickel ferrite composite nanoparticles: a biomaterial system. Acta Biomater. 2008;4(2):273–83. https://doi.org/10.1016/j.actbio.2007.07.002.
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P., S.V.V.S.N., P., S.V.V.S. A Review on Surface Modifications and Coatings on Implants to Prevent Biofilm. Regen. Eng. Transl. Med. 6, 330–346 (2020). https://doi.org/10.1007/s40883-019-00116-3
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DOI: https://doi.org/10.1007/s40883-019-00116-3