Skip to main content
SpringerLink
Log in

2D Material Chemistry: Graphdiyne-based Biochemical Sensing

  • Review
  • Published:
Chemical Research in Chinese Universities Aims and scope

Abstract

The modern internet-of-things era has witnessed an increasing growth in the demand for advanced sensors to collect precise information. To meet this demand, extensive efforts have been devoted to exploring competent materials and designing rational architectures for the fabrication of sensing devices. Graphdiyne represents a promising material due to the attractive electronic, optical and electrochemical properties deriving from its unique molecular structure. In this review, we firstly provide the points of view on the architectures and work principles of the graphdiyne-based sensing devices with respect to resistive, electrochemical, photoelectrochemical and fluorescent categories. Secondly, we present the promising applications on biochemical sensing, such as the detection of DNA, micro-RNA, and glucose. Finally, the challenges and prospects of graphdiyne-based biochemical sensing platforms are also discussed, in order to provide a cornerstone for understanding this rapidly developing area.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Classen C., International Social Science Journal, 1997, 49, 401

    Google Scholar 

  2. Liu Y., He K., Chen G., Leow W. R., Chen X., Chem. Rev., 2017, 117, 12893

    CAS  PubMed  Google Scholar 

  3. Wan C., Cai P., Wang M., Qian Y., Huang W., Chen X., Adv. Mater., 2020, 32, 1902434

    CAS  Google Scholar 

  4. Jiang Y., Liu Z., Wang C., Chen X., Acc. Chem. Res., 2019, 52, 82

    CAS  PubMed  Google Scholar 

  5. Wang T., Qi D., Yang H., Liu Z., Wang M., Leow W. R., Chen G., Yu J., He K., Cheng H., Wu Y. L., Zhang H., Chen X., Adv. Mater., 2019, 31, 1803883

    Google Scholar 

  6. Wan C., Chen G., Fu Y., Wang M., Matsuhisa N., Pan S., Pan L., Yang H., Wan Q., Zhu L., Chen X., Adv. Mater., 2018, 30, 1801291

    Google Scholar 

  7. Ji S., Wan C., Wang T., Li Q., Chen G., Wang J., Liu Z., Yang H., Liu X., Chen X., Adv. Mater., 2020, 32, 2001496

    CAS  Google Scholar 

  8. Wang T., Yang H., Qi D., Liu Z., Cai P., Zhang H., Chen X., Small, 2018, 14, 1702933

    Google Scholar 

  9. Pan S., Liu Z., Wang M., Jiang Y., Luo Y., Wan C., Qi D., Wang C., Ge X., Chen X., Adv. Mater., 2019, 31, 1903130

    Google Scholar 

  10. Chen G., Cui Y., Chen X., Chem. Soc. Rev., 2019, 48, 1434

    CAS  PubMed  Google Scholar 

  11. Amoli V., Kim J. S., Jee E., Chung Y. S., Kim S. Y., Koo J., Choi H., Kim Y., Kim D. H., Nat. Commun., 2019, 10, 4019

    PubMed  PubMed Central  Google Scholar 

  12. Tyagi D., Wang H., Huang W., Hu L., Tang Y., Guo Z., Ouyang Z., Zhang H., Nanoscale, 2020, 12, 3535

    CAS  PubMed  Google Scholar 

  13. Jiang P., Li Y., Ju T., Cheng W., Xu J., Han K., Chem. Res. Chinese Universities, 2020, 36(2), 307

    CAS  Google Scholar 

  14. Bolotsky A., Butler D., Dong C., Gerace K., Glavin N. R., Muratore C., Robinson J. A., Ebrahimi A., ACS Nano, 2019, 13, 9781

    CAS  PubMed  Google Scholar 

  15. Rohaizad N., Mayorga-Martinez C. C., Sofer Z., Pumera M., ACS Appl. Mater. Interfaces, 2017, 9, 40697

    CAS  PubMed  Google Scholar 

  16. Meng Z., Stolz R. M., Mendecki L., Mirica K. A., Chem. Rev., 2019, 119, 478

    CAS  PubMed  Google Scholar 

  17. Li G., Li Y., Liu H., Guo Y., Li Y., Zhu D., Chem. Commun., 2010, 46, 3256

    CAS  Google Scholar 

  18. Xu J., Jiang H., Shen Y., Li X. Z., Wang E. G., Meng S., Nat. Commun., 2019, 10, 3971

    PubMed  PubMed Central  Google Scholar 

  19. Long M., Tang L., Wang D., Li Y., Shuai Z., ACS Nano, 2011, 5, 2593

    CAS  PubMed  Google Scholar 

  20. Zheng Q., Luo G., Liu Q., Quhe R., Zheng J., Tang K., Gao Z., Nagase S., Lu J., Nanoscale, 2012, 4, 3990

    CAS  PubMed  Google Scholar 

  21. Srinivasu K., Ghosh S. K., J. Phys. Chem. C, 2012, 116, 5951

    CAS  Google Scholar 

  22. Luo G., Qian X., Liu H., Qin R., Zhou J., Li L., Gao Z., Wang E., Mei W. N., Lu J., Li Y., Nagase S., Phys. Rev. B, 2011, 84, 075439

    Google Scholar 

  23. Li Y., Xu L., Liu H., Li Y., Chem. Soc. Rev., 2014, 43, 2572

    CAS  PubMed  Google Scholar 

  24. Shang H., Zuo Z., Li L., Wang F., Liu H., Li Y., Li Y., Angew Chem. Int. Ed, 2018, 57, 774

    CAS  Google Scholar 

  25. Chen Y., Li J., Wang F., Guo J., Jiu T., Liu H., Li Y., Nano Energy, 2019, 64, 103932

    CAS  Google Scholar 

  26. Zhao Y., Yang N., Yao H., Liu D., Song L., Zhu J., Li S., Gu L., Lin K., Wang D., J. Am. Chem. Soc., 2019, 141, 7240

    CAS  PubMed  Google Scholar 

  27. Hui L., Xue Y., Yu H., Liu Y., Fang Y., Xing C., Huang B., Li Y., J. Am. Chem. Soc., 2019, 141, 10677

    CAS  PubMed  Google Scholar 

  28. Xue Y., Huang B., Yi Y., Guo Y., Zuo Z., Li Y., Jia Z., Liu H., Li Y., Nat. Commun., 2018, 9, 1460

    PubMed  PubMed Central  Google Scholar 

  29. Li J., Chen Y., Gao J., Zuo Z., Li Y., Liu H., Li Y., ACS Appl. Mater. Interfaces, 2019, 11, 2591

    CAS  PubMed  Google Scholar 

  30. Gao X., Ren H., Zhou J., Du R., Yin C., Liu R., Peng H., Tong L., Liu Z., Zhang J., Chem. Mater., 2017, 29, 5777

    CAS  Google Scholar 

  31. Xue Z., Yang H., Gao J., Li J., Chen Y., Jia Z., Li Y., Liu H., Yang W., Li Y., Li D., ACS Appl. Mater. Interfaces, 2016, 8, 21563

    CAS  PubMed  Google Scholar 

  32. Li G., Li Y., Qian X., Liu H., Lin H., Chen N., Li Y., The Journal of Physical Chemistry C, 2011, 115, 2611

    CAS  Google Scholar 

  33. Zheng Z., Fang H., Liu D., Tan Z., Gao X., Hu W., Peng H., Tong L., Hu W., Zhang J., Adv. Sci., 2017, 4, 1700472

    Google Scholar 

  34. Zhang Y., Huang P., Guo J., Shi R., Huang W., Shi Z., Wu L., Zhang F., Gao L., Li C., Zhang X., Xu J., Zhang H., Adv. Mater., 2020, 32, 2001082

    CAS  Google Scholar 

  35. Wu L., Dong Y., Zhao J., Ma D., Huang W., Zhang Y., Wang Y., Jiang X., Xiang Y., Li J., Feng Y., Xu J., Zhang H., Adv. Mater., 2019, 31, e1807981

    PubMed  Google Scholar 

  36. Guo J., Shi R., Wang R., Wang Y., Zhang F., Wang C., Chen H., Ma C., Wang Z., Ge Y., Song Y., Luo Z., Fan D., Jiang X., Xu J., Zhang H., Laser & Photonics Reviews, 2020, 14, 1900367

    CAS  Google Scholar 

  37. Qiu H., Xue M., Shen C., Zhang Z., Guo W., Adv. Mater., 2019, 31, e1803772

    PubMed  Google Scholar 

  38. Jiang W., Zhang Z., Wang Q., Dou J., Zhao Y., Ma Y., Liu H., Xu H., Wang Y., Nano Lett., 2019, 19, 4060

    CAS  PubMed  Google Scholar 

  39. Li S., Chen Y., Liu H., Wang Y., Liu L., Lv F., Li Y., Wang S., Chem. Mater., 2017, 29, 6087

    CAS  Google Scholar 

  40. Liu J., Wang L., Shen X., Gao X., Chen Y., Liu H., Liu Y., Yin D., Liu Y., Xu W., Cai R., You M., Guo M., Wang Y., Li J., Li Y., Chen C., Nano Today, 2020, 34, 100907

    Google Scholar 

  41. Du Y., Zhou W., Gao J., Pan X., Li Y., Acc. Chem. Res., 2020, 53, 459

    CAS  PubMed  Google Scholar 

  42. Gao X., Liu H., Wang D., Zhang J., Chem. Soc. Rev., 2019, 48, 908

    CAS  PubMed  Google Scholar 

  43. Huang C., Li Y., Wang N., Xue Y., Zuo Z., Liu H., Li Y., Chem. Rev., 2018, 118, 7744

    CAS  PubMed  Google Scholar 

  44. Jia Z., Li Y., Zuo Z., Liu H., Huang C., Li Y., Acc. Chem. Res., 2017, 50, 2470

    CAS  PubMed  Google Scholar 

  45. Guo S., Yan H., Wu F., Zhao L., Yu P., Liu H., Li Y., Mao L., Anal. Chem., 2017, 89, 13008

    CAS  PubMed  Google Scholar 

  46. Zhao L., Jiang Y., Hao J., Wei H., Zheng W., Mao L., Science China Chemistry, 2019, 62, 1414

    CAS  Google Scholar 

  47. Guo S., Yu P., Li W., Yi Y., Wu F., Mao L., J. Am. Chem. Soc., 2020, 142, 2074

    CAS  PubMed  Google Scholar 

  48. Zhang Y., Xie Q., Xia Z., Gui G., Deng F., J. Electroanal. Chem., 2020, 863

  49. Wu L., Gao J., Lu X., Huang C., Dhanjai, Chen J., Carbon, 2020, 156, 568

    CAS  Google Scholar 

  50. Pardo-Yissar V., Katz E., Wasserman J., Willner I., J. Am. Chem. Soc., 2003, 125, 622

    CAS  PubMed  Google Scholar 

  51. Luo Z., Qi Q., Zhang L., Zeng R., Su L., Tang D., Anal. Chem., 2019, 91, 4149

    CAS  PubMed  Google Scholar 

  52. Shu J., Tang D., Anal. Chem., 2020, 92, 363

    CAS  PubMed  Google Scholar 

  53. Li Y., Li X., Meng Y., Hun X., Biosens. Bioelectron., 2019, 130, 269

    CAS  PubMed  Google Scholar 

  54. Li X., Li Y., Zhang J., Meng Y., Yu X., Wang X., Hun X., Sensors and Actuators B: Chemical, 2019, 297, 126808

    CAS  Google Scholar 

  55. Wang H., Deng K., Xiao J., Li C., Zhang S., Li X., Sensors and Actuators B: Chemical, 2020, 304, 127363

    Google Scholar 

  56. Wang C., Yu P., Guo S., Mao L., Liu H., Li Y., Chem. Commun., 2016, 52, 5629

    CAS  Google Scholar 

  57. Xiao K., Li J., Wu X., Liu H., Huang C., Li Y., Carbon, 2019, 144, 72

    CAS  Google Scholar 

  58. Cranford S. W., Brommer D. B., Buehler M. J., Nanoscale, 2012, 4, 7797

    CAS  PubMed  Google Scholar 

  59. Wang S. S., Liu H. B., Kan X. N., Wang L., Chen Y. H., Su B., Li Y. L., Jiang L., Small, 2017, 13, 1602265

    Google Scholar 

  60. Yan H., Guo S., Wu F., Yu P., Liu H., Li Y., Mao L., Angew. Chem. Int. Ed., 2018, 57, 3922

    CAS  Google Scholar 

  61. Liu J., Shen X., Baimanov D., Wang L., Xiao Y., Liu H., Li Y., Gao X., Zhao Y., Chen C., ACS Appl. Mater. Interfaces, 2019, 11, 2647

    CAS  PubMed  Google Scholar 

  62. Zhuang X., Mao L., Li Y., Electrochem. Commun., 2017, 83, 96

    CAS  Google Scholar 

  63. Wang X., Xiong Z., Liu Z., Zhang T., Adv. Mater., 2015, 27, 1370

    CAS  PubMed  Google Scholar 

  64. Wang J., Liu G., Jan M. R., J. Am. Chem. Soc., 2004, 126, 3010

    CAS  PubMed  Google Scholar 

  65. Lu C. H., Yang H. H., Zhu C. L., Chen X., Chen G. N., Angew. Chem. Int. Ed., 2009, 48, 4785

    CAS  Google Scholar 

  66. Zhu C., Zeng Z., Li H., Li F., Fan C., Zhang H., J. Am. Chem. Soc., 2013, 135, 5998

    CAS  PubMed  Google Scholar 

  67. Zhang Y., Zheng B., Zhu C., Zhang X., Tan C., Li H., Chen B., Yang J., Chen J., Huang Y., Wang L., Zhang H., Adv. Mater., 2015, 27, 935

    CAS  PubMed  Google Scholar 

  68. He S., Song B., Li D., Zhu C., Qi W., Wen Y., Wang L., Song S., Fang H., Fan C., Adv. Funct. Mater., 2010, 20, 453

    CAS  Google Scholar 

  69. Chen X., Gao P., Guo L., Zhang S., Sci. Rep., 2015, 5, 16720

    CAS  PubMed  PubMed Central  Google Scholar 

  70. Parvin N., Jin Q., Wei Y., Yu R., Zheng B., Huang L., Zhang Y., Wang L., Zhang H., Gao M., Zhao H., Hu W., Li Y., Wang D., Adv. Mater., 2017, 29, 1606755

    Google Scholar 

  71. Hussain T., Sajjad M., Singh D., Bae H., Lee H., Larsson J. A., Ahuja R., Karton A., Carbon, 2020, 163, 213

    CAS  Google Scholar 

  72. Nagarajan V., Srimathi U., Chandiramouli R., Comput. Theor. Chem., 2018, 1123, 119

    CAS  Google Scholar 

  73. Chandra S. S., Swathi R. S., J. Phys. Chem. C, 2014, 118, 4516

    Google Scholar 

  74. Chang F., Huang L., Guo C., Xie G., Li J., Diao Q., ACS Appl. Mater. Interfaces, 2019, 11, 35622

    CAS  PubMed  Google Scholar 

  75. Dave V. P., Ngo T. A., Pernestig A. K., Tilevik D., Kant K., Nguyen T., Wolff A., Bang D. D., Lab. Invest., 2019, 99, 452

    CAS  PubMed  Google Scholar 

  76. Liu H., Guo J., Guo M., Wang F., Jin W., Chen C., Li Y., Angew Chem. Int. Ed, 2020, DOI: https://doi.org/10.1002/anie.202006891

Download references

Author information

Authors and Affiliations

  1. College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen, 518060, P. R. China

    Jiaofu Li & Han Zhang

  2. Innovative Centre for Flexible Devices(iFLEX), Max Planck-NTU Joint Lab for Artificial Senses, School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore, 639798, Singapore

    Jiaofu Li, Changjin Wan, Cong Wang & Xiaodong Chen

Authors
  1. Jiaofu Li
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Changjin Wan
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Cong Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Han Zhang
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Xiaodong Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Han Zhang or Xiaodong Chen.

Additional information

Supported by the State Key Research Development Program of China(No.2019YFB2203503) and the National Natural Science Foundation of China(Nos.61875138, 61961136001, U1801254)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Li, J., Wan, C., Wang, C. et al. 2D Material Chemistry: Graphdiyne-based Biochemical Sensing. Chem. Res. Chin. Univ. 36, 622–630 (2020). https://doi.org/10.1007/s40242-020-0181-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s40242-020-0181-4

Keywords

Search

Navigation