Abstract
The senior author (BG) introduced the modern concept of migraine surgery in 2000. Since then, over 40 articles have been published by eight centers across the US, Europe, and Asia, describing positive outcomes after surgery in 68–95% of cases. Surgeons, neurologists, and patients are increasingly interested in this new treatment method. However, the majority of publications on this topic are found in surgical literature, with few articles presented in neurology journals. This review is an introduction to migraine surgery for neurologists from a surgeons view. It discusses the surgical treatment of migraine headaches based on the discoveries made and articles published by the senior author. It outlines the current history of migraine surgery, presents evidence supporting its effectiveness, and tries to dispel claims that what we are seeing is a placebo effect. It further describes detection of trigger sites and outlines surgical techniques of peripheral nerve decompression. We hope that this review will generate a positive discussion between surgeons and neurologists and lead to more interdisciplinary collaboration for the benefit of the patients in the future.
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References
Guyuron B, Varghai A, Michelow BJ, Thomas T, Davis J (2000) Corrugator supercilii muscle resection and migraine headaches. Plast Reconstr Surg 106(2):429–434 (discussion 435–427)
Silberstein S, Mathew N, Saper J, Jenkins S (2000) Botulinum toxin type A as a migraine preventive treatment. For the BOTOX Migraine Clinical Research Group. Headache 40(6):445–450
Behmand RA, Tucker T, Guyuron B (2003) Single-site botulinum toxin type a injection for elimination of migraine trigger points. Headache 43(10):1085–1089
Moskowitz MA, Reinhard JF Jr, Romero J, Melamed E, Pettibone DJ (1979) Neurotransmitters and the fifth cranial nerve: is there a relation to the headache phase of migraine? Lancet 2(8148):883–885
Guyuron B, Tucker T, Davis J (2002) Surgical treatment of migraine headaches. Plast Reconstr Surg 109(7):2183–2189
Mosser SW, Guyuron B, Janis JE, Rohrich RJ (2004) The anatomy of the greater occipital nerve: implications for the etiology of migraine headaches. Plast Reconstr Surg 113(2):693–697. doi:10.1097/01.PRS.0000101502.22727.5D (discussion 698–700)
Behin F, Behin B, Behin D, Baredes S (2005) Surgical management of contact point headaches. Headache 45(3):204–210. doi:10.1111/j.1526-4610.2005.05045.x
Guyuron B, Kriegler JS, Davis J, Amini SB (2005) Comprehensive surgical treatment of migraine headaches. Plast Reconstr Surg 115(1):1–9
Guyuron B, Kriegler JS, Davis J, Amini SB (2011) Five-year outcome of surgical treatment of migraine headaches. Plast Reconstr Surg 127(2):603–608. doi:10.1097/PRS.0b013e3181fed456
Guyuron B, Reed D, Kriegler JS, Davis J, Pashmini N, Amini S (2009) A placebo-controlled surgical trial of the treatment of migraine headaches. Plast Reconstr Surg 124(2):461–468. doi:10.1097/PRS.0b013e3181adcf6a
Kam-Hansen S, Jakubowski M, Kelley JM, Kirsch I, Hoaglin DC, Kaptchuk TJ, Burstein R (2014) Altered placebo and drug labeling changes the outcome of episodic migraine attacks. Sci Transl Med 6(218):218ra215. doi:10.1126/scitranslmed.3006175
Liu MT, Armijo BS, Guyuron B (2012) A comparison of outcome of surgical treatment of migraine headaches using a constellation of symptoms versus botulinum toxin type A to identify the trigger sites. Plast Reconstr Surg 129(2):413–419. doi:10.1097/PRS.0b013e31823aecb7
Faber C, Garcia RM, Davis J, Guyuron B (2012) A socioeconomic analysis of surgical treatment of migraine headaches. Plast Reconstr Surg 129(4):871–877. doi:10.1097/PRS.0b013e318244217a
Chepla KJ, Oh E, Guyuron B (2012) Clinical outcomes following supraorbital foraminotomy for treatment of frontal migraine headache. Plast Reconstr Surg 129(4):656e–662e. doi:10.1097/PRS.0b013e3182450b64
Liu MT, Chim H, Guyuron B (2012) Outcome comparison of endoscopic and transpalpebral decompression for treatment of frontal migraine headaches. Plast Reconstr Surg 129(5):1113–1119. doi:10.1097/PRS.0b013e31824a2c31
Chmielewski L, Liu MT, Guyuron B (2013) The role of occipital artery resection in the surgical treatment of occipital migraine headaches. Plast Reconstr Surg 131(3):351e–356e. doi:10.1097/PRS.0b013e31827c6f71
Lee M, Monson MA, Liu MT, Reed D, Guyuron B (2013) Positive botulinum toxin type a response is a prognosticator for migraine surgery success. Plast Reconstr Surg 131(4):751–757. doi:10.1097/PRS.0b013e3182818b7f
Lee M, Lineberry K, Reed D, Guyuron B (2013) The role of the third occipital nerve in surgical treatment of occipital migraine headaches. J Plast Reconstr Aesthet Surg 66(10):1335–1339. doi:10.1016/j.bjps.2013.05.023
Molavi S, Zwiebel S, Gittleman H, Alleyne B, Guyuron B (2014) The effect of preoperative migraine headache frequency on surgical outcomes. Plast Reconstr Surg 134(6):1306–1311. doi:10.1097/PRS.0000000000000728
Lineberry K, Lee M, Monson A, Guyuron B (2015) Intraoperative corticosteroid injections in migraine surgery: efficacy in preventing refractory symptoms. Plast Reconstr Surg 135(2):393e–396e. doi:10.1097/PRS.0000000000000862
Guyuron B, Harvey D, Reed D (2015) A prospective randomized outcomes comparison of two temple migraine trigger site deactivation techniques. Plast Reconstr Surg 136(1):159–165. doi:10.1097/PRS.0000000000001322
Janis JE, Barker JC, Javadi C, Ducic I, Hagan R, Guyuron B (2014) A review of current evidence in the surgical treatment of migraine headaches. Plast Reconstr Surg 134(4 Suppl 2):131S–141S. doi:10.1097/PRS.0000000000000661
Gfrerer L, Maman DY, Tessler O, Austen WG Jr (2014) Nonendoscopic deactivation of nerve triggers in migraine headache patients: surgical technique and outcomes. Plast Reconstr Surg 134(4):771–778. doi:10.1097/PRS.0000000000000507
Peled ZM (2016) A novel surgical approach to chronic temporal headaches. Plast Reconstr Surg 137(5):1597–1600. doi:10.1097/PRS.0000000000002051
Lin SH, Lin HC, Jeng CH, Hsieh CH, Lin YH, Chen CC (2016) Experience of surgical treatment for occipital migraine in Taiwan. Ann Plast Surg 76(Suppl 1):S80–S84. doi:10.1097/SAP.0000000000000697
Guyuron B, Yohannes E, Miller R, Chim H, Reed D, Chance MR (2014) Electron microscopic and proteomic comparison of terminal branches of the trigeminal nerve in patients with and without migraine headaches. Plast Reconstr Surg 134(5):796e–805e. doi:10.1097/PRS.0000000000000696
Guyuron B, Lineberry K, Nahabet EH (2015) A retrospective review of the outcomes of migraine surgery in the adolescent population. Plast Reconstr Surg 135(6):1700–1705. doi:10.1097/PRS.0000000000001270
Punjabi A, Brown M, Guyuron B (2016) Emergence of secondary trigger sites after primary migraine surgery. Plast Reconstr Surg 137(4):712e–716e. doi:10.1097/PRS.0000000000002011
Guyuron B, Nahabet E, Khansa I, Reed D, Janis JE (2015) The current means for detection of migraine headache trigger sites. Plast Reconstr Surg 136(4):860–867. doi:10.1097/PRS.0000000000001572
Guyuron B, Riazi H, Long T, Wirtz E (2015) Use of a Doppler signal to confirm migraine headache trigger sites. Plast Reconstr Surg 135(4):1109–1112. doi:10.1097/PRS.0000000000001102
Fallucco M, Janis JE, Hagan RR (2012) The anatomical morphology of the supraorbital notch: clinical relevance to the surgical treatment of migraine headaches. Plast Reconstr Surg 130(6):1227–1233. doi:10.1097/PRS.0b013e31826d9c8d
Janis JE, Hatef DA, Ducic I, Ahmad J, Wong C, Hoxworth RE, Osborn T (2010) Anatomy of the auriculotemporal nerve: variations in its relationship to the superficial temporal artery and implications for the treatment of migraine headaches. Plast Reconstr Surg 125(5):1422–1428. doi:10.1097/PRS.0b013e3181d4fb05
Lee M, Brown M, Chepla K, Okada H, Gatherwright J, Totonchi A, Alleyne B, Zwiebel S, Kurlander D, Guyuron B (2013) An anatomical study of the lesser occipital nerve and its potential compression points: implications for surgical treatment of migraine headaches. Plast Reconstr Surg 132(6):1551–1556. doi:10.1097/PRS.0b013e3182a80721
Totonchi A, Pashmini N, Guyuron B (2005) The zygomaticotemporal branch of the trigeminal nerve: an anatomical study. Plast Reconstr Surg 115(1):273–277
Dash KS, Janis JE, Guyuron B (2005) The lesser and third occipital nerves and migraine headaches. Plast Reconstr Surg 115(6):1752–1758 (discussion 1759–1760)
Janis JE, Ghavami A, Lemmon JA, Leedy JE, Guyuron B (2007) Anatomy of the corrugator supercilii muscle: part I. Corrugator topography. Plast Reconstr Surg 120(6):1647–1653. doi:10.1097/01.prs.0000282725.61640.e1
Janis JE, Hatef DA, Thakar H, Reece EM, McCluskey PD, Schaub TA, Theivagt C, Guyuron B (2010) The zygomaticotemporal branch of the trigeminal nerve: part II. Anatomical variations. Plast Reconstr Surg 126(2):435–442. doi:10.1097/PRS.0b013e3181e094d7
Janis JE, Hatef DA, Ducic I, Reece EM, Hamawy AH, Becker S, Guyuron B (2010) The anatomy of the greater occipital nerve: part II. Compression point topography. Plast Reconstr Surg 126(5):1563–1572. doi:10.1097/PRS.0b013e3181ef7f0c
Janis JE, Ghavami A, Lemmon JA, Leedy JE, Guyuron B (2008) The anatomy of the corrugator supercilii muscle: part II. Supraorbital nerve branching patterns. Plast Reconstr Surg 121(1):233–240. doi:10.1097/01.prs.0000299260.04932.38
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Lisa Gfrerer has no financial disclosures. Bahman Guyuron is CEO of Innovative Medical Equipment and receives royalties for the books: Plastic Surgery Indications and Practice, Elsevier, Guyuron Rhinoplasty, Aesthetic Surgery Video Atlas.
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Gfrerer, L., Guyuron, B. Surgical treatment of migraine headaches. Acta Neurol Belg 117, 27–32 (2017). https://doi.org/10.1007/s13760-016-0731-1
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DOI: https://doi.org/10.1007/s13760-016-0731-1