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Nanomaterials for Wound Healing

  • Wound Care and Healing (A Friedman, Section Editor)
  • Published:
Current Dermatology Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

Despite the emergence of various new wound care products, millions of people continue to suffer from complications associated with acute and chronic wounds. Nanomaterials offer a variety of strategies to accelerate wound closure and promote appropriate progression through the stages of healing, which will be detailed in this review.

Recent Findings

The small size of nanomaterials enhances penetration and permeation of tissues and lends a large surface area-to-volume ratio, ideal for topical drug delivery. Furthermore, nanofibers may be utilized to create nanoscaffold wound dressings that simulate the topographic appearance of endogenous extracellular matrix, thereby stimulating wound reepithelialization and collagen production.

Summary

Together, nanomaterials offer many approaches to reduce the morbidity associated with acute and chronic wounds, as demonstrated by a substantial body of pre-clinical data. Future investigations should aim to address the paucity of human clinical trial data, essential for translating wound-healing benefits from bench to bedside.

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Authors and Affiliations

  1. Division of Dermatology, Department of Medicine, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY, 10461, USA

    Breanne Mordorski

  2. Dermatology Research Centre, Translational Research Institute, University of Queensland, 37 Kent Street, Woolloongabba, Brisbane, Queensland, 4102, Australia

    Tarl Prow

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  1. Breanne Mordorski
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  2. Tarl Prow
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Correspondence to Tarl Prow.

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Tarl Prow and Breanne Mordorski declare they have no conflicts of interest.

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This article does not contain any studies with human or animal subjects performed by any of the authors.

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This article is part of the Topical Collection on Wound Care and Healing

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Mordorski, B., Prow, T. Nanomaterials for Wound Healing. Curr Derm Rep 5, 278–286 (2016). https://doi.org/10.1007/s13671-016-0159-0

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