Skip to main content
Log in

Formulation, characterization and in vitro evaluation of herbal sunscreen lotion

  • Research Article
  • Published:
Oriental Pharmacy and Experimental Medicine Aims and scope Submit manuscript

Abstract

Natural substances extracted from plants have recently been considered as potential sunscreen resources owing to high ultraviolet ray absorption and antioxidant activity. The decrease in the intensity of UV radiation reaching the skin through sunscreens may reduce the risk of sun-induced skin cancer. The present study attempts to develop sunscreen lotions, possessing broad spectrum of anti-UV radiation effectiveness with reduced concentration of chemical UV filters, from the extracts of bioactive products such as Curcuma longa L. (Zingiberaceae), Aloe vera (Liliaceae) and Alpinia galanga Willd. The effectiveness of the product was evaluated using Sun Protection Factor (SPF). Curcumin was selected as potential bioactive agents due to their phytochemical compositions possessing considerable content of polyphenolic compounds and Alpinia galanga is used as key ingredient in various commercial sunscreen lotions as it has skin protectant action against UV rays and boosts the activity of conventional sunscreens. The sunscreen lotions were prepared using three different compositions F1, F2 and F3 and evaluated for their stability, safety and SPF. Results showed that the sunscreen lotions were non-mutagenic, non-irritant, stable and possess SPF for normal skin. The efficacy when tested with a standard was observed to be same as that of a marketed sunscreen with SPF 55 and SPF 20. From the present study, formulation F2 having curcumin extract was proved to be stable and effective with high SPF compared to F1 and F3.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  • Aburjai T, Natsheh FM (2003) Plants used in cosmetics. Phytotherapy Res 17:987–1000

    Article  Google Scholar 

  • Ashawat MS, Saraf S, Swarnlata S (2006) Sunscreen properties of natural skin care lotion. Bioscie Biotechnl Res Asia 6:253–256

    Google Scholar 

  • Ashawat MS, Saraf S, Swarnlata S (2005) Antisolar activity of R Damnesia and T. Errecta. Planta Indica 2:26–28

    Google Scholar 

  • Baby AR, Maciel CPM, Kaneko TM, Velasco MVR (2006) UV-spectrophotometric determination of bioflavonoids from a semisolid pharmaceutical dosage form containing Trichilia catigua Adr. Juss (and) Ptychopetalum olacoides Bentham standardized extract: analytical method validation and statistical procedure. J AOAC Int 89:1532–1537

    PubMed  CAS  Google Scholar 

  • Banov D, Baby AR, Bosco LM, Kaneko TM, Velasco MVR (2006) Caracterizac¸ ão do extrato seco de Ginkgo biloba L. em formulac¸ ões de uso tópico. Acta Farm Bonaerense 25:219–224

    CAS  Google Scholar 

  • Butler H (2000) Poucher's perfumes, cosmetics and soap. quality, stability and safety assurance. Kluwer Academic Publishers, Dordrecht, pp 507–621

    Google Scholar 

  • COLIPA (2006) COLIPA Guidelines: International Sun Protection Factor (SPF) Test Method

  • Deep C, Saraf S (2008) Novel approaches in herbal cosmetics. J Cosmet Dermatol 7:89–95

    Article  Google Scholar 

  • Faurschou A, Wulf HC (2007) The relation between sun protection factor and amount of sunscreen applied in vivo. Br J Dermatol 156:716–719

    Article  PubMed  CAS  Google Scholar 

  • F’guyer S, Afaq F, Mukhtar H (2003) Photochemoprevention of skin cancer by botanical agents. Photodermatol Photoimmunol Photomed 19:56–72

    Article  PubMed  Google Scholar 

  • Gaspar LR, Maia Campos PMBG (2003) Rheological behavior and the SPF of sunscreens. Int J Pharma 250:35–44

    Article  CAS  Google Scholar 

  • Henry MD (1997) Baird ed. Manual of cosmetic analysis. Analysis of creams and lotions. USA, pp 32–33

  • Hiremath SSP, Dasankoppa FS, Nadaf A, Jamakandi VG, Mulla JS, Sreenivas SA, Sholapur HN, Ahmed A, Nanjunda Swamy NG (2008) Formulation and evaluation of a novel in situ gum based ophthalmic drug delivery system of linezolid. Sci Pharm 76:515–532

    Article  CAS  Google Scholar 

  • Katiyar SK, Elment CA (2002) Green tea polyphenolic antioxidants and skin photoprotection. Int J Oncol 18:1307–1313

    Google Scholar 

  • King A, Young G (1999) Characteristics and occurrence of phenolic phytochemicals. J Am Diet Assoc 99:213–8

    Article  PubMed  CAS  Google Scholar 

  • Mansaur JS (1986) Determinacao d fator de proteaco solar por espectrofotometria. Anal Bras Dermatol 61:121–4

    Google Scholar 

  • Maron DM, Ames BN (1983) Revised methods for Salmonella mutagenicity assay test. Mutat Res 113:173–215

    Article  PubMed  CAS  Google Scholar 

  • Movileanu L, Neagoe I, Flonta ML (2000) Interaction of the antioxidant flavonoid quercetin with planar lipid bilayers. Int J Pharm 205:135–146

    Article  PubMed  CAS  Google Scholar 

  • Multimer M (1956) Spreadability determination by an apparatus. J Am Pharm Asso 45:212–214

    Article  Google Scholar 

  • Onodera S, Yoshimatsu K, Saitoh H, Uchida A (1998) Behavior of mutagenic formation from phenolic compounds in water disinfection with chlorine and their mutagenic potential formation. Jpn J Toxicol Environ Health 44:289–299

    Article  CAS  Google Scholar 

  • Robbins RJ (2003) Phenolic acids in foods: An overview of analytical methodology. J Agric Food Chem 31:2866–87

    Article  Google Scholar 

  • Rolim A, Oishi T, Maciel CPM, Zague V, Pinto CASO, Kaneko TM, Consiglieri VO, Velasco MVR (2006) Total flavonoids quantification from O/W emulsion with extract of Brazilian plants. Int J Pharm 308:107–114

    Article  PubMed  CAS  Google Scholar 

  • Sagarin E (1957) Cosmetics, Science, and Technology. Interscience Publishers, Inc, New York, p 1014

    Google Scholar 

  • Santo EP, Freitas ZM, Souza KR, Garcia S (1999) In vitro and in vivo determinations of sun protection factors of sunscreen lotions with octyl methoxycinnamate. Int J Cos Sci 21:1–5

    Article  Google Scholar 

  • Sayre MR, Stanfield J, Lott DL, Dowdy JC (2003) Simplified method to substantiate SPF labelling for sunscreen products. Photodermatol Photoimmunol Photomed 19:254–260

    Article  PubMed  CAS  Google Scholar 

  • Sayre RM (1993) Correlation of in vivo tests, in vitro SPF predictions - a survey of published studies. Cosmetics& Toiletries 108:111–114

    Google Scholar 

  • Shrivastava S, Kapoor S, Saraf S (2003) Novel preparation and evaluation of lotion containing aloe gel beads. Ind J Pharm Edu Res 42(2):77–80

    Google Scholar 

  • Tabrizi H, Mortazavi SA, Kamalinejad M (2003) An in vitro evaluation of various Rosa damascena flower extracts as natural antisolar agent. Int J Cosmet Sci 25:259–265

    Article  PubMed  CAS  Google Scholar 

  • Velasco MVR, Balogh TS, Pedriali CA, Sarruf FD, Pinto CASO, Kaneko TM, Baby AR (2008) Associac¸ ão da rutina com p-metoxicinamato de octila e benzofenona-3: avaliac¸ ão in vitro da eficácia fotoprotetora por espectrofotometria de refletância. Lat Am J Pharm 27:23–27

    CAS  Google Scholar 

  • Verschooten L, Declercq L, Garmyn M (2006) Adaptive response of the skin to UVB damage: role of the p53 protein. Int J Cosmet Sci 28:1–7

    Article  PubMed  CAS  Google Scholar 

Download references

Acknowledgements

The authors express their sincere thanks to Padmashri Dr. M. MohanBabu, Chairman, Sree Vidyanikethan Educational Trust, Tirupati, India for providing the necessary facilities to carry out this work.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Arun Rasheed.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Rasheed, A., Shama, S.N., Mohanalakshmi, S. et al. Formulation, characterization and in vitro evaluation of herbal sunscreen lotion. Orient Pharm Exp Med 12, 241–246 (2012). https://doi.org/10.1007/s13596-012-0069-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13596-012-0069-z

Keywords

Navigation