Abstract
Background and aim
Previous research studies have shown that poorly controlled type 2 diabetes patients do not receive insulin therapy because of the resistance of the patients to insulin therapy. This study aimed to assess the belief of Caribbean insulin-naïve type 2 diabetes patients on insulin therapy.
Methods
Five hundred ten insulin-naïve type 2 diabetes patients who have had diabetes for at least 5 years were recruited for a questionnaire interview. The questionnaire was a modified version of a previously validated research questionnaire. Data collected was analysed with SPSS software using chi-square to test for significances.
Results
The majority of the patients have had diabetes for > 10 years and take > 2 different diabetes medications daily. About 67% and 81% of the patients do not believe that insulin therapy will cause them hypoglycemia and weight gain respectively. Similarly, a significant percentage does not believe that taking insulin will interfere with their normal lifestyle activities (72.2%, p = 0.048). Although a majority (64%) of the patients believe that taking insulin translates to personal failure in optimal blood glucose control, 90% do not believe that taking insulin will cause people to treat them differently. A majority of the patients do not believe that taking insulin will be helpful in preventing long-term diabetes complications (63.9%, p = 0.001), though 51% thought it would make them feel better.
Conclusion
Contrary to several reports, this study shows that insulin-naïve Caribbean type 2 diabetes patients do not have a significant negative perception towards insulin therapy. This finding might be related to the socio-cultural background of the patients studied.
Similar content being viewed by others
References
Ezenwaka C, Onuoha P, Olukoga A. Challenges of self-monitoring of blood glucose in Caribbean type-2 diabetes patients. Int J Diabetes Dev Ctries. 2013;33(3):178–80.
Ezenwaka CE, Nwagbara E, Seales D, Okali F, Hussaini S, Raja B, et al. A comparative study of the prevalence of components of the metabolic syndrome in type 2 diabetic patients in two Caribbean Islands using the New International Diabetes Federation definition. Arch Physiol Biochem. 2007;113(4–5):202–10.
Ezenwaka CE, Kalloo R. Postprandial glucose control in type 2 diabetic patients visiting two different primary care clinics in Trinidad, West Indies. West Indian Med J. 2004;53(6):392–9.
Ezenwaka CE, Okoye O, Esonwune C, Onuoha P, Dioka C, Osuji C, et al. High prevalence of abdominal obesity increases the risk of the metabolic syndrome in Nigerian type 2 diabetes patients: using the IDF world-wide definition. Metab Syndr Relat Disord. 2014;12(5):277–82.
Ezenwaka CE, Okoye O, Esonwune C, Dioka C, Onuoha P, Osuji C, et al. Is diabetes patients’ knowledge of laboratory tests for monitoring blood glucose levels associated with better glycemic control? Arch Physiol Biochem. 2014;120(2):86–90.
UK Prospective Diabetes Study (UKPDS) Group. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). Lancet. 1998;352:837–53.
Home PD, Boulton AJM, Jimenez J, Landgraf R, Osterbrink B, Christiansen JS. Issues relating to the early or earlier use of insulin in type 2 diabetes. Practical Diabetes Int. 2003;20:63–71.
Brown JB, Nichols GA, Perry A. The burden of treatment failure in type 2 diabetes. Diabetes Care. 2004;27:1535–40.
Dailey GE. Early insulin: an important therapeutic strategy. Diabetes Care. 2005;28:220–1.
Davidson MB. Early insulin therapy for type 2 diabetes. Diabetes Care. 2005;28:222–4.
Peyrot M, Rubin RR, Lauritzen T, Skovlund SE, Snoek FJ, Matthews DR, et al. Resistance to insulin therapy among patients and providers: results of the cross-national diabetes attitudes, wishes and needs (DAWN) study. Diabetes Care. 2005;28:2673–9.
Leslie CA, Satin-Rapaport W, Matheson D, Stone R, Enfield G. Psychological insulin resistance: a missed diagnosis? Diabetes Spectrum. 1994;7:52–7.
Leslie CA, Satin-Rapaport W. Psychological insulin resistance: a challenge for diabetes patients and health care professionals. J of New Developments Clin Med. 1995;13:21–7.
Rubin R, Peyrot M. Psychological issues and treatments in people with diabetes. J Clin Psychol. 2001;57:457–78.
Korytkowski M. When oral agents fail: practical barriers to starting insulin. Int J Obes. 2002;26(Suppl. 3):S18–24.
Koerbel G, Korytkowski M. Insulin-therapy resistance: another form of insulin resistance in type 2 diabetes. Practical Diabetology. 2003;22:36–40.
Peyrot M. Psychological insulin resistance: overcoming barriers to insulin therapy. Practical Diabetology. 2004;23:6–12.
Funnell MM, Kruger DF, Spencer M. Self-management support for insulin therapy in type 2 diabetes. Diabetes Educ. 2004;30:274–80.
Polonsky WH, Jackson RA. What’s so tough about taking insulin? Addressing the problem of psychological insulin resistance in type 2 diabetes. Clinical Diabetes. 2004;22:147–50.
Ogbera AO, Kuku SF. Insulin use, prescription pattern, regimens and cost – a narrative from a developing country. Diabetol Metab Syndr. 2012;4:50. https://doi.org/10.1186/1758-5996-4-50.
Enwere OO, Salako BL, Falade CO. Prescription and cost consideration at a diabetic clinic in Ibadan, Nigeria: a report. Annals of Ibadan Postgraduate Medicine. 2006;4:32–6.
Sobngwi E, Ndour-Mbaye M, Boateng KA, Ramaiya KL, Njenga EW, Diop SN, et al. Type 2 diabetes control and complications in specialized diabetes care centres of six sub-Saharan African countries: the Diabcare Africa study. Diabetes Res Clin Pract. 2012;95(1):30–6.
Escalada J, DomingoOrozco-Beltran D, Morillas C, Alvarez-Guisasola F, Gomez-Peralta F, Mata-Cases M, et al. Attitudes towards insulin initiation in type 2 diabetes patients among healthcare providers: a survey research. Diabetes Res Clin Pract. 2016;122:46–53.
Miller GJ, Maude GH, Beckles GLA. Incidence of hypertension and non-insulin dependent diabetes mellitus and associated risk factors in a rapidly developing Caribbean community: the St James survey, Trinidad. J Epidemiol Community Health. 1996;50:497–504.
Ezenwaka CE, Offiah NV. Differences in glycemic control and cardiovascular risk in primary care patients with type 2 diabetes in West Indies. Clin Exp Med. 2001;1(2):91–8.
Ezenwaka CE. Metabolic control of type 2 diabetic patients commonly treated with sulphonylureas in a developing country. East Afr Med J. 2003;80(4):175–80.
Ezenwaka C, Nwagbara E, Seales D, Okali F, Hussaini S, Bn R, et al. Prediction of 10-year coronary heart disease risk in Caribbean type 2 diabetic patients using the UKPDS Risk Engine. Int J Cardiol. 2009;132:348–53.
National Institute of Diabetes and Digestive and Kidney Diseases. https://www.niddk.nih.gov/health-information/diabetes/overview/preventing-problems/low-blood-glucose-hypoglycemia. Accessed on 23rd November 2018.
Insulin myths and facts: clinical diabetes. 2007;25(1):39–40. https://doi.org/10.2337/diaclin.25.1.39
Polonsky WH, Anderson BJ, Lohrer PA, Aponte JE, Jacobson AM, Cole CF. Insulin omission in women with IDDM. Diabetes Care. 1994;17:1178–85.
Brod M, Alolga SL, Meneghini L. Barriers to initiating insulin in type 2 diabetes patients: development of a new patient education tool to address myths, misconceptions and clinical realities. Patient. 2014;7:437–50.
Brod M, Kongsø JH, Lessard S, Christensen TL. Psychological insulin resistance: patient beliefs and implications for diabetes management. Qual Life Res. 2009;18(1):23–32.
United Kingdom Prospective Diabetes Study (UKPDS). Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group. Lancet. 1998;352(9131):854–65.
Ezenwaka C, Eckel J. Prevention of diabetes complications in developing countries: time to intensify self-management education. Arch Physiol Biochem. 2011;117(5):251–3.
Central Statistical Office, Republic of Trinidad and Tobago. http://cso.gov.tt/statistics/; Accessed on 23rd November 2018.
Acknowledgment
We are grateful to the Chief Executive Officers of North-West, North-Central and Eastern Regional Health Authorities for the permission to conduct this study within their Regional Health Authorities. We thank the patients for their time in completing the questionnaire interviews.
Funding
This study was sponsored through the University of the West Indies Research and Publication Fund grant to the authors.
Author information
Authors and Affiliations
Contributions
CEE: contributed in the concept, design, data analysis, data acquisition, statistical analysis, manuscript preparation and writing
PO: design, data analysis, data acquisition, manuscript preparation and review
SY: design, data acquisition, statistical analysis, manuscript preparation and review
RE: design, data analysis, statistical analysis, manuscript preparation and review
Corresponding author
Ethics declarations
The study protocol was reviewed and approved by the University of the West Indies Ethics Review Committee.
Conflict of interest
The authors declare that they have no conflict of interest.
Additional information
Publisher’s note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Ezenwaka, C.E., Onuoha, P., Extavour, R. et al. Beliefs of Caribbean type 2 diabetes patients towards insulin therapy and prescription. Int J Diabetes Dev Ctries 40, 442–448 (2020). https://doi.org/10.1007/s13410-020-00808-5
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s13410-020-00808-5