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Biocompatible Ag nanoparticle-embedded poly(2-hydroxyethyl methacrylate) derivative films with bacterial adhesion-resistant and antibacterial properties

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Abstract

Polymeric nanocomposite films of poly(2-hydroxyethyl methacrylate) (PHEMA) derivative, with ester side groups containing well-dispersed Ag nanoparticles, were prepared, using a very simple coating and reduction process. The nanocomposite films were stable in water because the matrix polymer, PHEMA derivative with ester side groups is relatively hydrophobic, while Ag nanoparticles are well dispersed in the polymer matrix, due to the oxygen-rich ester side groups of the polymer. By integrating the antibacterial effect of Ag nanoparticles onto the bacterial adhesion-resistant and biocompatible characters of the PHEMA derivative, polymer-Ag nanocomposite films having biocompatible, bacterial adhesion-resistant, and antibacterial properties could be produced. Moreover, a very small amount of Ag nanoparticles was found to greatly increase the stability of the polymer film in water, a leading to extending the applicable window in biological fields.

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References

  1. L. Hall-Stoodley, J. W. Costerton, and P. Stoodley, Nat. Rev. Microbiol., 2, 95 (2004).

    Article  CAS  Google Scholar 

  2. I. Banerjee, R. C. Pangule, and R. S. Kane, Adv. Mater., 23, 690 (2011).

    Article  CAS  Google Scholar 

  3. K. D. Park, Y. S. Kim, D. K. Han, Y. H. Kim, E. H. B. Lee, H. Suh, and K. S. Choi, Biomaterials 19, 851 (1998).

    Google Scholar 

  4. G. Cheng, H. Xite, Z. Zhang, S. F. Chen, and S. Y. Jiang, Angew. Chem. Int. Ed., 47, 8831 (2008).

    Article  CAS  Google Scholar 

  5. E.-H. Sohn, J. Kim, B. G. Kim, J. I. Kang, J. S. Chung, J. Ahn, J. Yoon, J.-C. Lee, Colloids Surf. B, 77, 191 (2010).

    Article  CAS  Google Scholar 

  6. S. B. Lee, R. R. Koepsel, S. W. Morley, K. Matyjaszewski, Y. J. Sunand, and A. J. Russell, Biomacromolecules, 5, 877 (2004).

    Article  CAS  Google Scholar 

  7. G. Mary, S. K. Bajpai, and N. Chand, J. Appl. Polym. Sci., 113, 757 (2009).

    Article  CAS  Google Scholar 

  8. E.-H. Sohn, J. Ahn, S. H. Bhang, J. Kang, J. Yoon, B.-S. Kim, and J.-C. Lee, Macromol. Biosci., 12, 211 (2012).

    Article  CAS  Google Scholar 

  9. E.-H. Sohn, M. Lee, and K. Song, Macromol. Res., 21, 234 (2013).

    Article  CAS  Google Scholar 

  10. H. Y. Lee, H. K. Park, Y. M. Lee, K. Kim, and S. B. Park, Chem. Commun., 46, 2959 (2007).

    Article  Google Scholar 

  11. P. V. AshaRani, G. L. K. Mun, M. P. Hande, and S. Valiyaveettil, ACS Nano 3, 279 (2009).

    Google Scholar 

  12. M.-H. Youn, Y.-M. Lim, H.-J. Gwon, J.-S. Park, S.-J. An, and Y.-C. Nho, Macromol. Res., 17, 813 (2009).

    Article  CAS  Google Scholar 

  13. I. Sondi and B. Salopek-Sondi, J. Colloid Interface Sci. 275, 177 (2004).

    Google Scholar 

  14. J. S. Kim, E. Kuk, K. N Yu, J. H. Kim, S. J. Park, H. J. Lee, S. H. Kim, Y. K. Park, Y. H. Park, C.-Y. Hwang, Y. K. Kim, Y. S. Lee, D. H. Jeong, and M. H. Cho, Nanomedicine, 3, 95 (2007).

    Article  CAS  Google Scholar 

  15. D. W. Hatchett and S. Henry, J. Phys. Chem., 100, 9854 (1996).

    Article  CAS  Google Scholar 

  16. R. de Lima, A. B. Seabra, and N. Durán, J. Appl. Toxicol., 32, 867 (2012).

    Article  CAS  Google Scholar 

  17. X. Yang, A. P. Gondikas, S. M. Marinakos, M. Auffan, J. Liu, G. H. Kim, and J. N. Meyer, Environ. Sci. Technol., 46, 1119 (2012).

    Article  CAS  Google Scholar 

  18. X. Ge, Y. Leng, C. Bao, S. L. Xu, R. Wang, and F. Ren, J. Biomed. Mater. Res., 95A, 588 (2010).

    Article  CAS  Google Scholar 

  19. Friend of Industry Technology Information (FITI) Testing & Research Institute, Antibacterial of polymeric materials (FC-TM-20). 2001.

  20. H.-J. Jeon, S.-C. Yi, and S.-G. Oh. Biomaterials, 24, 4921 (2003).

    Article  CAS  Google Scholar 

  21. R. Mihai, I. P. Florescu, V. Coroiu, A. Oancea, and M. Lungu, J. Med. Life, 4, 250 (2011).

    CAS  Google Scholar 

  22. L. M. Liz-Marzan and I. Lado-Tourino, Langmuir, 12, 3585 (1996).

    Article  CAS  Google Scholar 

  23. D. Zhang, L. Qi, J. Ma, and H. Cheng, Chem. Mater., 13, 2753 (2001).

    Article  CAS  Google Scholar 

  24. C. Chen, T. Serizawa, and M. Akashi, Langmuir, 15, 7998 (1999).

    Article  CAS  Google Scholar 

  25. S. Y. Kang and K. Kim, Langmuir, 14, 226 (1998).

    Article  CAS  Google Scholar 

  26. C. W. Chou, S. Hsu, and H. Chang, S.-M. Tseng, and H.-R. Lin, Polym. Degrad. Stab., 91, 1017 (2006).

    Article  CAS  Google Scholar 

  27. Z. H. Mbhele, M. G. Salemane, C. G. C. E. van Sittert, J. M. Nedeljkovic, V. Djokovic, and A. S. Luyt, Chem. Mater., 15, 5019 (2003).

    Article  CAS  Google Scholar 

  28. Z.-C. Xing, W.-P. Chae, J.-Y. Baek, M.-J. Choi, Y. Jung, and I.-K. Kang, Biomacromolecules, 11, 1248 (2010).

    Article  CAS  Google Scholar 

  29. A. Agarwal, T. L. Weis, M. J. Schurr, N. G. Faith, C. J. Czuprynski, J. F. McAnulty, C. J. Murphy, and N. L. Abbott, Biomaterials, 31, 680 (2010).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Chemical and Biological Engineering and Institute of Chemical Processes, Seoul National University, Seoul, 151-744, Korea

    Jooyeon Ahn, Suk Ho Bang, Junil Kang, Taeyoung Kim, Hyunkee Hong, Seong-Eun Kim, Byung-Soo Kim, Jeyong Yoon & Jong-Chan Lee

  2. Interface Materials and Engineering Laboratory, Korea Research Institute of Chemical Technology, Daejon, 305-343, Korea

    Eun-Ho Sohn

Authors
  1. Jooyeon Ahn
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  2. Eun-Ho Sohn
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  3. Suk Ho Bang
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  4. Junil Kang
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  5. Taeyoung Kim
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Correspondence to Jong-Chan Lee.

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These authors contributed equally.

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Ahn, J., Sohn, EH., Bang, S.H. et al. Biocompatible Ag nanoparticle-embedded poly(2-hydroxyethyl methacrylate) derivative films with bacterial adhesion-resistant and antibacterial properties. Macromol. Res. 22, 337–343 (2014). https://doi.org/10.1007/s13233-014-2050-9

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  • DOI: https://doi.org/10.1007/s13233-014-2050-9

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