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Probiotics—Live Biotherapeutics: a Story of Success, Limitations, and Future Prospects—Not Only for Humans

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Abstract

In livestock production, lactic acid bacteria (LAB) represent the most widespread microorganisms used as probiotics. For such critical use, these bacteria must be correctly identified and characterized to ensure their safety and efficiency. Recently, probiotics have become highly recognized as supplements for humans and in particular for animals because of their beneficial outcome on health improvement and well-being maintenance. Various factors, encompassing dietary and management constraints, have been demonstrated to tremendously influence the structure, composition, and activities of gut microbial communities in farm animals. Previous investigations reported the potential of probiotics in animal diets and nutrition. But a high rate of inconsistency in the efficiency of probiotics has been reported. This may be due, in a major part, to the dynamics of the gastrointestinal microbial communities. Under stressing surroundings, the direct-fed microbials may play a key role as the salient limiting factor of the severity of the dysbiosis caused by disruption of the normal intestinal balance. Probiotics are live microorganisms, which confer health benefits on the host by positively modifying the intestinal microflora. Thus, the aim of this review is to summarize and to highlight the positive influence of probiotics and potential probiotic microbe supplementation in animal feed with mention of several limitations.

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  1. Unité de Protéomique Fonctionnelle et Potentiel Nutraceutique de la Biodiversité de Tunisie, Institut Supérieur des Sciences Biologiques Appliquées de Tunis, Université de Tunis El-Manar, 1006, Tunis, Tunisia

    Mohamed Zommiti & Mounir Ferchichi

  2. Health Promoting Naturals Laboratory, School of Environmental and Biological Sciences, Rutgers State University, New Brunswick, NJ, USA

    Michael L. Chikindas

  3. Center for Digestive Health, New Jersey Institute for Food, Nutrition, and Health, New Brunswick, NJ, USA

    Michael L. Chikindas

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Zommiti, M., Chikindas, M.L. & Ferchichi, M. Probiotics—Live Biotherapeutics: a Story of Success, Limitations, and Future Prospects—Not Only for Humans. Probiotics & Antimicro. Prot. 12, 1266–1289 (2020). https://doi.org/10.1007/s12602-019-09570-5

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