Skip to main content

Advertisement

SpringerLink
Log in

Intracystic papilloma of the breast forming a giant cyst

  • Case Report
  • Published:
Breast Cancer Aims and scope Submit manuscript

Abstract

Intracystic tumors of the breast prove to benign more often than malignant, and most intracystic lesions are benign papillomas. Generally, the cyst with intracystic papilloma of the breast is small, and there are few cases of intracystic papilloma of the breast forming a giant cyst in the literature. We report the case had the intracystic papilloma of the breast with a giant cyst (diameter of 15.0 cm). Imaging examinations showed two intracystic components in the cyst, and suggested that they were malignancy. Cytological examinations revealed no malignant cell. In spite of many aspirations of the cyst fluid, the size was not changed finally. The surgical resection was performed, and histological examination revealed two intracystic papillomas. In review of the literatures, it is difficult to distinguish between intracystic papilloma and intracystic papillary carcinoma by imaging or cytologic examinations preoperatively. Surgery should be recommended to confirm diagnosis and treatment.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4

Similar content being viewed by others

References

  1. Carter D, Orr SL, Merino MJ. Intracystic papillary carcinoma of the breast. After mastectomy, radiotherapy or excisional biopsy alone. Cancer. 1983;52:14–9.

    Article  CAS  PubMed  Google Scholar 

  2. Devitt JE, Barr JR. The clinical recognition of cystic carcinoma of the breast. Surg Gynecol Obstet. 1984;159:130–2.

    CAS  PubMed  Google Scholar 

  3. Hughes LE, Bundred NJ. Breast macrocysts. World J Surg. 1989;13:711–4.

    Article  CAS  PubMed  Google Scholar 

  4. Estabrook A, Asch T, Gump F, Kister SJ, Geller P. Mammographic features of intracystic papillary lesions. Surg Gynecol Obstet. 1990;170:113–6.

    CAS  PubMed  Google Scholar 

  5. Omori LM, Hisa N, Ohkuma K, Fujikura Y, Hiramatsu K, Enomoto I, et al. Breast masses with mixed cystic-solid sonographic appearance. J Clin Ultrasound. 1993;21:489–95.

    Article  CAS  PubMed  Google Scholar 

  6. Jeffrey PB, Ljung BM. Benign and malignant papillary lesions of the breast. A cytomorphologic study. Am J Clin Pathol. 1994;101:500–7.

    CAS  PubMed  Google Scholar 

  7. Kline TS, Kline IK. Breast. Guides to clinical aspiration biopsy. New York: Igaku-Shoin; 1989. p. 57–133.

    Google Scholar 

  8. Bardales RH, Suhrland MJ, Stanley MW. Papillary neoplasms of the breast: fine-needle aspiration findings in cystic and solid cases. Diagn Cytopathol. 1994;10:336–41.

    Article  CAS  PubMed  Google Scholar 

  9. Jones BM, Bradbeer JW. The presentation and progress of macroscopic breast cysts. Br J Surg. 1980;67:669–71.

    Article  CAS  PubMed  Google Scholar 

  10. Fallentin E, Rothman L. Intracystic carcinoma of the male breast. J Clin Ultrasound. 1994;22:118–20.

    Article  CAS  PubMed  Google Scholar 

  11. Rosemond GP, Maier WP, Brobyn TJ. Needle aspiration of breast cysts. Surg Gynecol Obstet. 1969;128:351–4.

    CAS  PubMed  Google Scholar 

  12. Yokoyama T, Yoshida T, Sugishima S. (1995) Cytologic studies on mammary cystic lesion with special reference to intracystic papilloma and intracystic carcinoma. J Jpn Soc Clin cytol 34:614–20 (in Japanese with English abstract).

    Google Scholar 

  13. Kihara M, Mori N, Yamauchi A, Yokomise H. A case of intracystic papillary carcinoma with a multilocular cyst of the breast in male. Breast Cancer.. 2004;11:409–12.

    Article  PubMed  Google Scholar 

  14. Inaji H, Koyama H, Motomura K, Noguchi S, Tsuji N, Kimura Y, et al. Simultaneous assay of ErbB–2 protein and carcinoembryonic antigen in cyst fluid as an aid in diagnosing cystic lesions of the breast. Breast Cancer. 1994;30:25–30.

    Article  Google Scholar 

  15. Yamamoto D, Ueda S, Senzaki H, Shoji T, Haijima H, Gondo H, et al. New diagnostic approach to intracystic lesions of the breast by fiberoptic ductoscopy. Anticancer Res. 2001;21:4113–6.

    CAS  PubMed  Google Scholar 

  16. Berna JD, Madrigal M, Hernandez J, Arcas I. Percutaneous endoscopy of an intracystic papilloma of the breast. Breast J. 2002;8:314–6.

    Article  PubMed  Google Scholar 

  17. Tsuda H, Uei Y, Fukutomi T, Hirohashi S. Different incidence of loss of heterozygosity on chromosome 16q between intraductal papilloma and intracystic papillary carcinoma of the breast. Jpn J Cancer Res. 1994;85:992–6.

    CAS  PubMed  Google Scholar 

  18. Hughes LE, Bundred NJ. Breast macrocysts. World J Surg. 1989;13:711–4.

    Article  CAS  PubMed  Google Scholar 

  19. Hinton CP, Williams MR, Roebuck EJ, Blamey RW. A controlled trial of danazol in the treatment of multiple recurrent breast cysts. Br J Clin Pract. 1986;40:368–70.

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Surgery, Kuma Hospital, 8-2-35 Shimoyamate-Dori, Chuo-Ku, Kobe, Hyogo, 650-0011, Japan

    Minoru Kihara & Akira Miyauchi

  2. Second Department of Surgery, Faculty of Medicine, Kagawa University, 1750-1, Ikenobe, Miki, Kagawa, 761-0793, Japan

    Minoru Kihara

Authors
  1. Minoru Kihara
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Akira Miyauchi
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Minoru Kihara.

About this article

Cite this article

Kihara, M., Miyauchi, A. Intracystic papilloma of the breast forming a giant cyst. Breast Cancer 17, 68–70 (2010). https://doi.org/10.1007/s12282-008-0092-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12282-008-0092-6

Keywords

Search

Navigation