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Biomolecule-templated photochemical synthesis of silver nanoparticles: Multiple readouts of localized surface plasmon resonance for pattern recognition

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Abstract

Silver nanoparticles (AgNPs) with distinct localized surface plasmon resonance (LSPR) absorption spectra can be synthesized using different proteins as templates upon irradiation by light. We utilized the multiple readouts of LSPR signals of AgNPs to construct sensor arrays for pattern recognition of proteins. Room temperature, aqueous solutions, and lack of harsh reducing reagents make the whole process inherently “green”. Meanwhile, the strategy efficiently simplified the process of array-receptor preparation and data acquisition, leading to lower time consumption, sample use, and cost. Furthermore, the system can differentiate proteins using flexible and alterable sensor elements by choosing different combinations of LSPR signals at different wavelengths. The principle of the sensor design can also be further extended to differentiate other biomolecules. The study provides a new method to construct feasible, economical, and general nanoparticle-based sensing arrays for pattern recognition.

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Acknowledgements

Financial support was provided by the National Natural Science Foundation of China (Nos. 21210002, 21673223, 21431007, and 21533008), and the Youth Innovation Promotion Association CAS (No. 2014202).

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Authors and Affiliations

  1. Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, China

    Fang Pu, Xiang Ran, Yanyan Huang, Jinsong Ren & Xiaogang Qu

  2. Cancer Center, First Affiliated Hospital, Jilin University, Changchun, 130061, China

    Meng Guan

  3. University of Chinese Academy of Sciences, Beijing, 100039, China

    Xiang Ran & Yanyan Huang

Authors
  1. Fang Pu
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  2. Xiang Ran
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  3. Meng Guan
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  5. Jinsong Ren
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  6. Xiaogang Qu
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Correspondence to Jinsong Ren or Xiaogang Qu.

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12274_2017_1819_MOESM1_ESM.pdf

Biomolecule-templated photochemical synthesis of silver nanoparticles: Multiple readouts of localized surface plasmon resonance for pattern recognition

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Pu, F., Ran, X., Guan, M. et al. Biomolecule-templated photochemical synthesis of silver nanoparticles: Multiple readouts of localized surface plasmon resonance for pattern recognition. Nano Res. 11, 3213–3221 (2018). https://doi.org/10.1007/s12274-017-1819-5

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  • DOI: https://doi.org/10.1007/s12274-017-1819-5

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