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High-risk mesothelioma relation to meteorological and geological condition and distance from naturally occurring asbestos

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Environmental Health and Preventive Medicine Aims and scope

An Erratum to this article was published on 29 January 2016

Abstract

Objectives

Very few studies have investigated the incidence and risk of malignant mesothelioma (MM) associated with distinct sources of asbestos exposure, especially exposure to naturally occurring asbestos (NOA).

Methods

Subjects were MM, lung, and breast cancer patients who were diagnosed and followed in Diyarbakir Province between 2008 and 2013. The birthplaces of patients were displayed on a geologic map. Geological and meteorological effects on MM were analyzed by logistic regression.

Results

A total of 180 MM, 368 breast, and 406 lung cancer patients were included. The median distance from birthplace to ophiolites was 6.26 km for MM, 31.06 km for lung, and 34.31 km for breast cancer (p < 0.001). The majority of MM cases were seen within 20 km from NOA areas. The MM incidence inside of NOA was 1059/100.000, and out of NOA was 397/100.000; this difference was significant (p = 0.014). The largest concentration of MM residential areas was within ±30° (34 residential areas 36.6 %) of the dominant wind direction. Most MM patients were found in or near the dominant wind direction, especially in the acute angle defined by the dominant wind direction. MM incidence was directly proportional to {[area of NOA (km2)] * [cosine α of wind direction angle]} and was inversely proportional to the square of the distance (R = 0.291, p = 0.023).

Conclusions

MM was higher near NOA and in the downwind direction. MM incidence and risk were affected by geological and meteorological factors.

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Acknowledgments

The research was not financially supported.

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Authors and Affiliations

  1. Medical School, Department of Chest Diseases, Dicle University, Diyarbakir, Turkey

    Abdurrahman Abakay, Abdullah Cetin Tanrikulu, Mahsuk Taylan & Ozlem Abakay

  2. Department of Mine Engineering, Dicle University, Diyarbakir, Turkey

    Mustafa Ayhan & Mehmet Sefik Imamoglu

  3. Medical School, Department of Medical Oncology, Dicle University, Diyarbakir, Turkey

    Muhammet Ali Kaplan

Authors
  1. Abdurrahman Abakay
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  2. Abdullah Cetin Tanrikulu
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  3. Mustafa Ayhan
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  4. Mehmet Sefik Imamoglu
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  5. Mahsuk Taylan
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  6. Muhammet Ali Kaplan
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  7. Ozlem Abakay
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Correspondence to Abdurrahman Abakay.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Dicle University Ethics Committee obtained ethical approval.

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Abakay, A., Tanrikulu, A.C., Ayhan, M. et al. High-risk mesothelioma relation to meteorological and geological condition and distance from naturally occurring asbestos. Environ Health Prev Med 21, 82–90 (2016). https://doi.org/10.1007/s12199-015-0501-3

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  • DOI: https://doi.org/10.1007/s12199-015-0501-3

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