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Efficient iron(III) porphyrins-catalyzed oxidation of guanidoximes to cyanamides in ionic liquids

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Abstract

Water soluble iron(III) porphyrins immobilized in imidazolium ionic liquids serve as an effective catalyst for the H2O2 mediated oxidation of guanidoximes to selectively give corresponding cyanamides in good yields. The use of ionic liquid with non-coordinating counter anion PF6 affords the product in high yield by facilitating the formation of anionic iron peroxo intermediate.

The selective oxidation of guanidoximes to corresponding cyanamides has been achieved by H2O2 catalyzed by water-soluble iron(III) porphyrins immobilized in imidazolium ionic liquids. The non-coordinating ionic liquid [bmim][PF6] facilitates the formation of anionic iron peroxo intermediate and thereby gives products in highest yield.

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Acknowledgements

The authors are grateful to the Council of Scientific and Industrial Research, New Delhi and University of Delhi for financial assistance.

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Authors and Affiliations

  1. Bioorganic Laboratory, Department of Chemistry, University of Delhi, Delhi, India, 110007

    PRATIBHA KUMARI, RITIKA NAGPAL, PRASHANT CHAUHAN, VINITH YATINDRANATH & SHIVE M S CHAUHAN

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  1. PRATIBHA KUMARI
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  2. RITIKA NAGPAL
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KUMARI, P., NAGPAL, R., CHAUHAN, P. et al. Efficient iron(III) porphyrins-catalyzed oxidation of guanidoximes to cyanamides in ionic liquids. J Chem Sci 127, 13–18 (2015). https://doi.org/10.1007/s12039-014-0751-4

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