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Conversion surgery for locally advanced malignant pleural mesothelioma

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Abstract

Two women in their sixties were diagnosed with inoperable locally advanced epithelioid malignant pleural mesothelioma, c-stage IIIB. Post-chemotherapy, the tumors down-staged to yc-stage IA, and pleurectomy/decortication were performed. The pathological diagnoses were p-stages II and IA. One patient had tumor recurrence 6 months after surgery; she is currently undergoing fourth-line chemotherapy and is alive 30 months postoperatively. The second patient had tumor recurrence 4 months after surgery and died 2 months later. Conversion surgery for advanced malignant mesothelioma does not improve progression-free survival but might have a chance to extend overall survival in selected patients without deteriorating performance status.

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Authors and Affiliations

  1. Division of Thoracic Surgery, Shizuoka Cancer Center, Shimonagakubo 1007, Nagaizumi-cho, Sunto-gun, Shizuoka, 411-8777, Japan

    Yukihiro Terada, Mitsuhiro Isaka, Hayato Konno, Hideaki Kojima, Tetsuya Mizuno & Yasuhisa Ohde

  2. Division of Thoracic Oncology, Shizuoka Cancer Center, Shizuoka, Japan

    Haruyasu Murakami

  3. Division of Pathology, Shizuoka Cancer Center, Shizuoka, Japan

    Takuya Kawata

Authors
  1. Yukihiro Terada
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  2. Mitsuhiro Isaka
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  3. Haruyasu Murakami
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  4. Takuya Kawata
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  5. Hayato Konno
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  6. Hideaki Kojima
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  7. Tetsuya Mizuno
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  8. Yasuhisa Ohde
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Correspondence to Yukihiro Terada.

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Terada, Y., Isaka, M., Murakami, H. et al. Conversion surgery for locally advanced malignant pleural mesothelioma. Gen Thorac Cardiovasc Surg 68, 1547–1550 (2020). https://doi.org/10.1007/s11748-020-01329-y

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  • DOI: https://doi.org/10.1007/s11748-020-01329-y

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