Abstract
Summary
Osteoporotic hip fractures are thought to be rare in Blacks however, this study from South Africa shows a significant increase in the number of hip fracture in Blacks. With the expected increase in older people, osteoporotic fractures will pose a major health problem and screening guidelines needed to be implemented.
Introduction
Developing countries are predicted to bear the burden of osteoporosis in the coming decades. This study was undertaken to review earlier reports that osteoporotic hip fractures are rare in Black Africans.
Methods
In an observational study, the incidence rates and relative risk ratios (RRR) of osteoporotic hip fractures were calculated in the Black population, aged 60 years and older, residing in the eThekwini region of South Africa. All Black subjects, presenting with a minimal trauma hip fracture to five public hospitals in the region, entered the study. Descriptive statistics were applied to show differences in age and sex.
Results
Eighty-seven subjects were enrolled in the study with a mean age of 76.5 ± 10.5 years and the sex ratio of women to men was 2.5:1. Although men were younger than women, this was not significant (74.2 ± 12.3 vs. 77.4 ± 9.6 years, p = 0.189). The age-adjusted rate was 69.2 per 100,000 p.a. for women and 73.1 per 100,000 p.a. for men. There was a significant increase in the relative risk ratios for hip fractures after the age of 75 years in the total cohort and in women and men. Except for the 65–69-year age group, there was no significant difference in the age-adjusted RRR between women and men.
Conclusion
This study represents the largest number of hip fractures recorded in Black Africans. Although the incidence rate is approximately tenfold higher than previously recorded, it remains amongst the lowest globally. A national registry inclusive of private and public sector is required to establish the true incidence rate of hip fractures in Black Africans.
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Funding
This study was funded by an unrestricted educational grant from Servier® and the University of Kwa-Zulu Natal.
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Ethical approval for the study was granted by the Biomedical Research Ethics Committee of University of KwaZulu-Natal (KZN), and study approval was obtained from the KZN Provincial Department of Health and from all the hospitals involved in the study. The study was conducted according to the ethical guidelines and principles of the International Declaration of Helsinki and South African Guidelines for Good Clinical Practice.
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Paruk, F., Matthews, G. & Cassim, B. Osteoporotic hip fractures in Black South Africans: a regional study. Arch Osteoporos 12, 107 (2017). https://doi.org/10.1007/s11657-017-0409-1
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DOI: https://doi.org/10.1007/s11657-017-0409-1