Skip to main content
SpringerLink
Log in

Preparation of elemental tellurium nanoparticles — sucrose sol and its antioxidant activity in vitro

  • Biomaterial
  • Published:
Journal of Wuhan University of Technology-Mater. Sci. Ed. Aims and scope Submit manuscript

Abstract

The elemental tellurium nanoparticles (TeNPs) — sucrose sol was prepared by the reaction of sodium tellurite with ascorbic acid in sucrose aqueous solution. The results indicated that TeNPs were dispersion excellent in the TeNPs — sucrose sol and the morphology of TeNPs was needle-like with about 70 nm in width and 500 nm in length. The antioxidant activity of the TeNPs — sucrose sol in vitro was estimated by pyrogallol autoxidation method, Fenton method and oxygen radical absorbance capacity (ORAC) assay. The results showed that a certain amount of TeNPs — sucrose sol could effectively scavenge superoxide anion free radical and hydroxyl free radical with scavenging rates of 73 % and 57 %, respectively. ORAC assay was used to measure the total antioxidant capacity of TeNPs — sucrose sol. The order of ORAC values was 2.25 μmol·L−1 TeNPs — 0.025 % sucrose sol > 0.025 % sucrose > 2.25 μmol·L−1 Na2TeO3 > 1.63 μmol·L−1 ascorbic acid. The results suggested that the TeNPs — sucrose sol had the excellent antioxidant activity and TeNPs were the dominating contributors to antioxidant capacity of the TeNPs — sucrose sol.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. R B Zheng, W L Cheng, E K Wang, et al. Synthesis of Tellurium Nanorods via Spontaneous Oxidation of NaHTe at Room Temperature[J]. Chemical Physics Letters, 2004, 395(4–6): 302–305

    Article  CAS  Google Scholar 

  2. Z P Liu, Z K Hu, Q Xie, et al. Surfactant-assisted Growth of Uniform Nanorods of Crystalline Tellurium[J]. Journal of Materials Chemistry, 2003, 13(1): 159–162

    Article  CAS  Google Scholar 

  3. H Zhang, D R Yang, X Y Ma, et al. Transformation Mechanism of Te Particles into Te Nanotubes and Nanowires during Solvothermal Process[J]. Journal of Crystal Growth, 2006,289(2): 568–573

    Article  CAS  Google Scholar 

  4. G C Xi, Y Y Peng, W C Yu, et al. Synthesis, Characterization, and Growth Mechanism of Tellurium Nanotubes[J]. NanotubesCrystal Growth & Design, 2005, 5(1): 325–328

    Article  CAS  Google Scholar 

  5. J Li, J H Zhang, Y T Qian. Surfactant-assisted Synthesis of Bundlelike Nanostructures with Well-aligned Te Nanorods[J]. Solid State Sciences, 2008, 10(11): 1 549–1 555

    Article  CAS  Google Scholar 

  6. J M Song, Y Z Lin, Y J Zhan, et al. Superlong High-Quality Tellurium Nanotubes: Synthesis, Characterization, and Optical Property[J]. Crystal Growth & Design, 2008, 8(6): 1 902–1 908

    CAS  Google Scholar 

  7. G Z Shen, D Chen, K B Tang, et al. A Rapid Route for the Synthesis of Submicron Se and Te Rod-like Crystals[J]. Materials Research Bulletin, 2004, 39(13): 2 077–2 082

    Article  CAS  Google Scholar 

  8. Z H Lin, Z S Yang, H T Chang. Preparation of Fluorescent Tellurium Nanowires at Room Temperature[J]. Crystal Growth & Design, 2008, 8(1): 351–357

    Article  CAS  Google Scholar 

  9. A Taylor. Biochemistry of Tellurium[J]. Biological Trace Element Research, 1996, 55(3): 231–239

    Article  CAS  Google Scholar 

  10. E P Painter. The Chemistry and Toxicity of Selenium Compounds with Special Reference to the Selenium Problem[J]. Chemical Reviews, 1941, 28(2): 179–213

    Article  CAS  Google Scholar 

  11. T G Chasteen, D E Fuentes, J C Tantaleán, et al. Tellurite: History, Oxidative Stress, and Molecular Mechanisms of Resistance[J]. FEMS Microbiology Reviews, 2009, 33(4): 820–832

    Article  CAS  Google Scholar 

  12. M P Rayman. The Importance of Selenium to Human Health[J]. LANCET, 2000, 356(9 225): 233–241

    Article  CAS  Google Scholar 

  13. K M Brown, J R Arthur. Selenium, Selenoproteins and Human Health: A Review[J]. Public Health Nutrition, 2001, 4(2B): 593–599

    Article  CAS  Google Scholar 

  14. H W Zeng, G F Combs. Selenium as an Anticancer Nutrient: Roles in Cell Proliferation and Tumor Cell Invasion[J]. Jouranl of Nutritional Biochemistry, 2008, 19(1): 1–7

    Article  Google Scholar 

  15. T Ishrat, K Parveen, M M Khan, et al. Selenium Prevents Cognitive Decline and Oxidative Damage in Rat Model of Streptozotocin- induced Experimental Dementia of Alzheimer’s Type[J]. Brain Research, 2009(1 281): 117–127

    Article  CAS  Google Scholar 

  16. B Huang, J S Zhang, J W Hou, et al. Free Radical Scavenging Efficiency of Nano -Se in Vitro[J]. Free Radical Biology and Medicine, 2003, 35(7): 805–813

    Article  CAS  Google Scholar 

  17. C Y Tone, C G Xue, X M Liu, et al. Research of Antioxidation of Red Nanose by Fluorescence Spectroscopy and Methylthianolyldiphenyltetrazolium Bromide Assay[J]. Chinese Journal of Analytical Chemistry, 2006, 34(12): 1 752–1 754

    Google Scholar 

  18. H L Wang, J S Zhang, H Q Yu. Elemental Selenium at Nano Size Possesses Lower Toxicity without Compromising the Fundamental Effect on Selenoenzymes: Comparison with Selenomethionine in Mice[J]. Free Radic Biology and Medicine, 2007, 42(10): 1 524–1 533

    CAS  Google Scholar 

  19. J S Zhang, X F Wang, T W Xu. Elemental Selenium at Nano Size (Nano-Se) as a Potential Chemopreventive Agent with Reduced Risk of Selenium Toxicity: Comparison with Se-Methylselenocysteine in Mice[J]. Toxicological Sciences, 2008, 101(1): 22–31

    Article  CAS  Google Scholar 

  20. S N Barnaby, S H Frayne, K R Fath, et al. Growth of Se Nanoparticles on Kinetin Assemblies and Their Biocompatibility Studies[J]. Soft Materials, 2011, 9(4): 313–334

    Article  CAS  Google Scholar 

  21. Y H Zhou, J Y Huang, Y Bai, et al. Antiox Idant Activity of Selenium Nanoparticles-sucrose Sol[J]. Journal of Jinan University (Natural Science & Medicine Edition), 2010, 31(1): 71–74

    Google Scholar 

  22. H Y Luo, Y H Zhou, Y Bai, et al. Antioxidant Activity of Selenium Nanoparticle-amino Acid Sols[J]. Food Science and Technology, 2011, 36(4): 202–206

    CAS  Google Scholar 

  23. Y Bai, B Y Qin, Y H Zhou, et al. Preparation and Antioxidant Capacity of Element Selenium Nanoparticles Sol-gel Compounds[J]. Journal of Nanoscience and Nanotechnology, 2011, 11(6): 5 012–5 017

    Article  CAS  Google Scholar 

  24. C W Nogueira, G Zeni, J B T Rocha. Organoselenium and Organotellurium Compounds: Toxicology and Pharmacology [J]. Chemical Reviews, 2004, 104(12): 6 255–6 285

    Article  CAS  Google Scholar 

  25. V P P Schiar, D B dos Santos, D S Lüdtke, et al. Screening of Potentially Toxic Chalcogens in Erythrocytes[J]. Toxicology in Vitro, 2007, 21(1): 139–145

    Article  CAS  Google Scholar 

  26. Y Ogra. Toxicometallomics for Research on the Toxicology of Exotic Metalloids Based on Speciation Studies[J]. Analytical Sciences, 2009, 25(10): 1 189–1 195

    Article  CAS  Google Scholar 

  27. W J Ding, T Hasegawa, D Peng, et al. Preliminary Investigation on the Cytotoxicity of Tellurite to Cultured HeLa Cells[J]. Journal of Trace Elements Medicine and Biology, 2002, 16(2): 99–102

    Article  CAS  Google Scholar 

  28. B Deuticke, P Lutkemeier, B Poser. Tellurite-induced Damage of the Erythrocyte Membrane. Manifestations and Mechanisms[J]. Biochimica Et Biophysica Acta, 1992, 1 109(1): 97–107

    Article  CAS  Google Scholar 

  29. S Kumar, L Engman, L Valgimigli, et al. Antioxidant Profile of Ethoxyquin and Some of S, Se, and Te Anologues[J]. Journal of Organic Chemistry, 2007, 72(16): 6 046–6 055

    CAS  Google Scholar 

  30. A C G Souza, C Luchese, J S Santos Neto, et al. Antioxidant Effect of a Novel Class of Telluroacetilene Compounds:studies in Vitro and in Vivo[J]. Life Science, 2009, 84(11–12): 351–357

    Article  CAS  Google Scholar 

  31. D Sredni-Kenigsbuch, M Shohat, B Shohat, et al. The Novel Tellurium Immunomodulator AS101 Inhibits Interleukin-10 Production and P38 MAPK Expression in Atopic Dermatitis[J]. Journal of Dermatological Science, 2008, 50(3): 232–235

    Article  CAS  Google Scholar 

  32. M Friedman, I Bayer, I Letko, et al. Topical Treatment for Human Papillomavirus- associated Genital Warts in Humans with the Novel Tellurium Immunomodulator AS101: Assessment of Its Safety and Efficacy[J]. British Journal of Demotology, 2009, 160(2): 403–408

    Article  CAS  Google Scholar 

  33. B L Sailer, N Liles, S Dickerson, et al. Cytometric Determination of Novel Organotellurium Compound Toxicity in a Promyelocytic (HL-60) Cell Line[J]. Archives of Toxicology, 2003, 77(1): 30–36

    Article  CAS  Google Scholar 

  34. B Mayers, Y N Xia. Formation of Tellurium Nanotubes through Concentration Depletion at the Surfaces of Seeds[J]. Advanced Materials, 2002, 14(4): 279–282

    Article  CAS  Google Scholar 

  35. S K Mahto, T P Vinod, J Kim, et al. Cytotoxic Potentials of Tellurium Nanowires in BALB/3T3 Fibroblast Cells[J]. Bulletin of the Korean Chemical Society, 2011, 32(9): 3 405–3 410

    Article  CAS  Google Scholar 

  36. E Alarcón, A M Campos, A M Edwards, et al. Antioxidant Capacity of Herbal Infusions and Tea extracts: A Comparison of ORAC-fluorescein and ORAC-pyrogallol Red Methodologies[J]. Food Chemistry, 2008, 107(3): 1 114–1 119

    Article  Google Scholar 

  37. J L Li, M Zhang, T S Zheng. The in Vitro Antioxidant Activity of Lotus Germ Oil from Supercritical Carbon Dioxide Extraction[J]. Food Chemistry, 2009, 115(3): 939–944

    Article  CAS  Google Scholar 

  38. M J Laughton, P J Evans, M A Moroney, et al. Inhibition of Mammalian 5-lipoxygenase and Cyclo-oxygenase by Flavonoids and Phenolic Dietary Additives. Relationship to Antioxidant Activity and to Iron Ion-reducing Ability[J]. Biochemical Pharmacology, 1991, 42(9); 1 673-1 681

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Chemistry, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China

    Yunzhi Li  (李云志), Jie Pan, Kun Jiang, Yanhui Zhou, Jietao Huang, Jinxuan Ye & Yan Bai  (白燕)

Authors
  1. Yunzhi Li  (李云志)
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Jie Pan
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Kun Jiang
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Yanhui Zhou
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Jietao Huang
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Jinxuan Ye
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Yan Bai  (白燕)
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Yan Bai  (白燕).

Additional information

Funded by the National Natural Science Foundation of China (No. 21075053)

Rights and permissions

Reprints and permissions

About this article

Cite this article

Li, Y., Pan, J., Jiang, K. et al. Preparation of elemental tellurium nanoparticles — sucrose sol and its antioxidant activity in vitro . J. Wuhan Univ. Technol.-Mat. Sci. Edit. 28, 1048–1052 (2013). https://doi.org/10.1007/s11595-013-0817-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11595-013-0817-z

Key words

Search

Navigation