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Copper Accumulation in Tissues of Oreochromis niloticus Exposed to Copper Oxide Nanoparticles and Copper Sulphate with Their Effect on Antioxidant Enzyme Activities in Liver

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Abstract

Copper accumulation in the gill, liver, kidney, spleen, and muscle tissues of Oreochromis niloticus was determined after exposing the fish to 10, 50, and 100 μg Cu/L applied as copper sulphate (CuSO4) and copper oxide nanoparticles (CuO NPs) after 1, 7, and 15 days. Changes in the liver SOD, CAT, and GPx activities influenced by this accumulation were also studied. No mortality was observed during the experiments. Copper levels increased in the gill, liver, kidney, and spleen tissues of O. niloticus compared to control when exposed to both CuSO4 and CuO NPs, whereas no accumulation was detected in muscle tissue at the end of the exposure period. Highest accumulation of copper was observed in the order of the liver, kidney, spleen, and gill tissues, respectively. SOD, CAT, and GPx activities increased in the liver tissue at the end of the exposure period. Overall, CuO NPs are more effective than CuSO4 in terms of tissue accumulation and liver enzyme activities.

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Acknowledgements

This work was supported by the Çukurova University, Scientific Research Projects Coordination Unit and The Scientific and Technological Research Council of Turkey. We also would like to acknowledge Prof. Dr. Maria João Bebianno, Asst. Prof. Dr. Margarida Ribau Teixeira, Dr. Tânia Gomes, and Vânia Sousa.

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  1. Faculty of Science and Letters, Biology Department, Çukurova University, Adana, Turkey

    Mustafa Tunçsoy & Cahit Erdem

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  1. Mustafa Tunçsoy
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  2. Cahit Erdem
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Correspondence to Mustafa Tunçsoy.

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Tunçsoy, M., Erdem, C. Copper Accumulation in Tissues of Oreochromis niloticus Exposed to Copper Oxide Nanoparticles and Copper Sulphate with Their Effect on Antioxidant Enzyme Activities in Liver. Water Air Soil Pollut 229, 269 (2018). https://doi.org/10.1007/s11270-018-3913-z

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