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Ferrocenes as potential anticancer drugs. Facts and hypotheses

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Russian Chemical Bulletin Aims and scope

Abstract

We analyzed the research data on antitumor effects of a wide range of ferrocene compounds and discussed possible mechanisms of their bioactivities. Current trends in the study of anticancer effects of ferrocene derivatives were considered. Promising ways in the design of low-toxicity anticancer ferrocene-based drugs of new generation were outlined.

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Authors and Affiliations

  1. A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 ul. Vavilova, 119991, Moscow, Russian Federation

    V. N. Babin, Yu. A. Belousov, V. V. Gumenyuk, Yu. S. Nekrasov, A. A. Simenel & L. V. Snegur

  2. Scientific Research Company “Ultrasan”, 4 build., 57 ul. 2-ya Peschanaya, 125252, Moscow, Russian Federation

    V. N. Babin

  3. Clinical Oncology Dispensary No. 1, 17/1 ul. Baumanskaya, 105005, Moscow, Russian Federation

    V. I. Borisov

  4. N. M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, 4 ul. Kosygina, 119334, Moscow, Russian Federation

    L. A. Ostrovskaya

  5. P. A. Herzen Moscow Research Institute of Oncology, 3 2-oi Botkinskii proezd, 125284, Moscow, Russian Federation

    I. K. Sviridova & N. S. Sergeeva

Authors
  1. V. N. Babin
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  2. Yu. A. Belousov
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  3. V. I. Borisov
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  4. V. V. Gumenyuk
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  5. Yu. S. Nekrasov
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  6. L. A. Ostrovskaya
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  7. I. K. Sviridova
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  8. N. S. Sergeeva
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  9. A. A. Simenel
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  10. L. V. Snegur
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Corresponding author

Correspondence to L. V. Snegur.

Additional information

Dedicated to the 60th anniversary of the A. N. Nesmeyanov Institute of Organoelement Compounds of the Russian Academy of Sciences (INEOS RAS). The review was written on the initiative and with the active participation of Yu. S. Nekrasov who served with good faith and fidelity for INEOS RAS for more than 40 years.

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 11, pp. 2405—2422, November, 2014.

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Babin, V.N., Belousov, Y.A., Borisov, V.I. et al. Ferrocenes as potential anticancer drugs. Facts and hypotheses. Russ Chem Bull 63, 2405–2422 (2014). https://doi.org/10.1007/s11172-014-0756-7

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  • DOI: https://doi.org/10.1007/s11172-014-0756-7

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