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Synthesis and evaluation of antioxidant and radical scavenging activities of quinolinobenzothiazinones

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Abstract

A new series of structurally diverse quinolinobenzothiazinones has been synthesized with the annulation of heterocyclic structural pharmacophores. The structures of the synthesized compounds were assigned on the basis of their analytical and spectral data. The synthesized quinolinobenzothiazinones were evaluated for their antioxidant (LPO and GSH) and radical scavenging activities (DPPH and ABTS assays).

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Acknowledgments

The authors are grateful to the Head, Department of Chemistry, University of Rajasthan, Jaipur, for providing necessary laboratory as well as instrumentation facilities. K.S., A.R., and S.K. thank UGC and CSIR New Delhi for fellowships.

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Authors and Affiliations

  1. Department of Chemistry, University of Rajasthan, Jaipur, 302055, India

    Mahendra Kumar, Kshitija Sharma, Anshu Rajawat & Sarita Khandelwal

  2. Department of Zoology, University of Rajasthan, Jaipur, 302055, India

    R. M. Samarth

  3. Department of Research, Bhopal Memorial Hospital & Research Centre (ICMR), Bhopal, 462038, India

    R. M. Samarth

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  1. Mahendra Kumar
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  2. Kshitija Sharma
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Correspondence to Mahendra Kumar.

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Kumar, M., Sharma, K., Rajawat, A. et al. Synthesis and evaluation of antioxidant and radical scavenging activities of quinolinobenzothiazinones. Res Chem Intermed 41, 2265–2276 (2015). https://doi.org/10.1007/s11164-013-1344-4

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  • DOI: https://doi.org/10.1007/s11164-013-1344-4

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