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On the biogenesis of marine isoprenoids

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Abstract

The isoprenoids comprise an important group among the marine natural products which are mainly obtained from soft corals, sponges and algae. The cembranes, xenia metabolites from soft corals and rearranged spongans from sponges are examples of marine diterpenoids obtained directly from GeGePP or after remarkable changes. Biogenesis, suggested biosynthesis, based on the structure and mainly known terrestrial biosynthesis, is proposed for diterpenoids and higher isoprenoids. Examples include the sipholanes, sodwanones and other triterpenoids as well as antheliolide and the T. toxius phenylhexaprenoide metabolites of mixed biogenetic origin.

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Authors and Affiliations

  1. School of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Ramat Aviv, 69978, Israel

    Yoel Kashman & Amira Rudi

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  1. Yoel Kashman
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  2. Amira Rudi
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Correspondence to Yoel Kashman.

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Kashman, Y., Rudi, A. On the biogenesis of marine isoprenoids. Phytochem Rev 3, 309–323 (2004). https://doi.org/10.1007/s11101-004-8062-x

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