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Konjac Glucomannan/Poly(vinyl alcohol)/Na+Rectorite Nanocomposite Films: Structure, Characteristic and Drug Delivery Behaviour

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Abstract

Konjac glucomannan(KGM)/poly(vinyl alcohol)(PVA)/Na+ modified rectorite (Na+REC) nanocomposite films were obtained by using a casting/solvent evaporation method. The structures and microstructures of KGM/PVA/Na+REC composite films were analyzed by FTIR, XRD, SEM and TEM. A wide variety of material characteristics for the KGM/PVA/Na+REC composite films were investigated, including the mechanical property, optical transmittance and thermal stability. The results revealed that by adding PVA more well-intercalative/exfoliated structure of composite film was obtained. As a result, the KGM/PVA/Na+REC composite film at low Na+REC and PVA content exhibited an improvement in mechanical properties and thermal stability due to a reinforcement effect. In vitro drug-controlled release studies showed a slower and more continuous release for KGM/PVA/Na+REC composite film in comparison with KGM/Na+REC composite film.

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Acknowledgments

This work was supported by the National Natural Science Foundation of China under Grant (No. 50573046), the Shaanxi Province Education Commission Foundation No. 12JK0610, Xianyang Science and Technology Bureau Foundation No. 2011k05-05, Xianyang Teacher’s College foundation No. 10XSYK103 and College students’ innovative projects of Xianyang Teacher’s College No. 2013036.

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Authors and Affiliations

  1. College of Chemistry and Chemical Engineering, Xianyang Teacher’ College, Xianyang, 712000, Shaanxi, People’s Republic of China

    Lianli Yang, Naini Guo & Yang Zhang

  2. Department of Applied Chemistry, School of Science, Northwestern Polytechnical University, Xi’an, 710072, Shaanxi, People’s Republic of China

    Xiaoyan Ma

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  1. Lianli Yang
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  2. Xiaoyan Ma
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  3. Naini Guo
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  4. Yang Zhang
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Correspondence to Lianli Yang.

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Yang, L., Ma, X., Guo, N. et al. Konjac Glucomannan/Poly(vinyl alcohol)/Na+Rectorite Nanocomposite Films: Structure, Characteristic and Drug Delivery Behaviour. J Inorg Organomet Polym 23, 1459–1467 (2013). https://doi.org/10.1007/s10904-013-9950-6

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  • DOI: https://doi.org/10.1007/s10904-013-9950-6

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