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Determination of pharmaceuticals and pesticides in river sediments and corresponding surface and ground water in the Danube River and tributaries in Serbia

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Abstract

The aim of this study was the development of analytical methods for the simultaneous determination of 25 selected pharmaceuticals, metabolites, and pesticides, belonging to the various chemical classes, in river sediments and their corresponding surface and ground water with the purpose of monitoring the contamination levels. The methods were based on the solid-phase extraction as the sample preparation method for water samples, and the ultrasonic solvent extraction for the sediment samples, followed by the liquid chromatography–tandem mass spectrometry. High recoveries were achieved for extraction from both water and sediment samples for the majority of analytes. Low limits of detection were achieved for all investigated compounds in the water sample (1–5 ng L−1) as well as in the sediment (1–3 ng g−1). Applicability of the developed methods was demonstrated by determination of pharmaceutical and pesticide residues in 30 surface water, 44 groundwater, and 5 sediment samples from the Danube River Basin in Serbia. Sixty percent of target compounds were detected in environmental samples. The most frequently detected analytes in river sediments were the pesticides dimethoate and atrazine, while carbamazepine and metamizole metabolites 4-AAA and 4-FAA were the most frequently found in water samples.

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Acknowledgments

This work was supported by the Ministry of Education, Science and Technological Development of the Republic of Serbia (Projects ON172007 and TR37014).

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Authors and Affiliations

  1. Faculty of Technology and Metallurgy, University of Belgrade, Karnegijeva 4, 11000, Belgrade, Serbia

    Tanja Radović, Svetlana Grujić & Mila Laušević

  2. Jaroslav Černi Institute for the Development of Water Resources, Jaroslava Černog 80, 11226, Belgrade, Serbia

    Anđelka Petković & Milan Dimkić

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  1. Tanja Radović
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  2. Svetlana Grujić
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  3. Anđelka Petković
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  4. Milan Dimkić
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  5. Mila Laušević
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Correspondence to Svetlana Grujić.

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Radović, T., Grujić, S., Petković, A. et al. Determination of pharmaceuticals and pesticides in river sediments and corresponding surface and ground water in the Danube River and tributaries in Serbia. Environ Monit Assess 187, 4092 (2015). https://doi.org/10.1007/s10661-014-4092-z

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