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Docetaxel Induced Sclerosing Cholangitis

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Abbreviations

CT:

Computer tomography

MRI:

Magnetic resonance imaging

LITs:

Liver injury tests

ADT:

Androgen deprivation therapy

References

  1. Sweeney C, Chen Y-H, Carducci MA, et al. Impact on overall survival (OS) with chemohormonal therapy versus hormonal therapy for hormone-sensitive newly metastatic prostate cancer (mPrCa): an ecog-led phase III randomized trial. J Clin Oncol. 2014;32:5s

    Article  Google Scholar 

  2. Taylor J, Lindor K. Metastatic prostate cancer simulating sclerosing cholangitis. J Clin Gastroenterol. 1993;16:143–145.

    Article  CAS  PubMed  Google Scholar 

  3. Bruno R, Hille D, Riva A, et al. Population pharmacokinetics/pharmacodynamics of docetaxel in phase ii studies in patients with cancer. J Clin Oncol. 1998;16:187–196.

    CAS  PubMed  Google Scholar 

  4. Hirth J, Watkins PB, Strawderman M, Schott A, Bruno R, Baker LH. The effect of an individual’s cytochrome cyp3a4 activity on docetaxel clearance. Clin Cancer Res. 2000;6:1255–1258.

    CAS  PubMed  Google Scholar 

  5. Wils P, Phung-Ba V, Warnery A, et al. Polarized transport of docetaxel and vinblastine mediated by p-glycoprotein in human intestinal epithelial cell monolayers. Biochem Pharmacol. 1994;48:1528–1530.

    Article  CAS  PubMed  Google Scholar 

  6. Lexicomp. Docetaxel: Drug information. 2015. http://www.uptodate.com/contents/docetaxel-drug-information?source=search_result&search=docetaxel&selectedTitle=1%7E150. Accessed 30 June 2015.

  7. Vodovar D, Mongardon N, Moachon L, et al. Severe docetaxel overdose induced by pharmacokinetic interaction with dronedarone. J Clin Oncol. 2011;29:e694–e695.

    Article  PubMed  Google Scholar 

  8. Ho RH, Kim RB. Transporters and drug therapy: implications for drug disposition and disease. Clin Pharmacol Ther. 2005;78:260–277.

    Article  CAS  PubMed  Google Scholar 

  9. Bjornsson TD, Callaghan JT, Einolf HJ, et al. The conduct of in vitro and in vivo drug–drug interaction studies: a phrma perspective. J Clin Pharmacol. 2003;43:443–469.

    Article  CAS  PubMed  Google Scholar 

  10. Imam MH, Talwalkar JA, Lindor KD. Secondary sclerosing cholangitis: pathogenesis, diagnosis, and management. Clin Liver Dis. 2013;17:269–277.

    Article  PubMed  Google Scholar 

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Correspondence to Hugo E. Vargas.

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Horsley-Silva, J.L., Dow, E.N., Menias, C.O. et al. Docetaxel Induced Sclerosing Cholangitis. Dig Dis Sci 60, 3814–3816 (2015). https://doi.org/10.1007/s10620-015-3914-3

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  • DOI: https://doi.org/10.1007/s10620-015-3914-3

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