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СН functionalization of (hetero)arenes with ethyne and ethene moieties

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Chemistry of Heterocyclic Compounds Aims and scope

This article provides an overview of the available literature data on direct CH functionalization reactions used for introducing alkenyl and alkynyl groups into heterocyclic systems. The information has been systematized according to the type of the experimental procedure and the nature of the (hetero)arene moiety. The time period covered in this review starts from the first example (according to our knowledge) when ethyne moiety was introduced into aza-heterocycles using СН functionalization in 1961, until the present time. A total of 100 references have been provided.

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This work was performed with financial support from the Russian Science Foundation (grant 18-13-00365).

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Authors and Affiliations

  1. Department of Organic and Biomolecular Chemistry, Chemical Engineering Institute, Ural Federal University named after the first President of Russia B. N. Yeltsin, 19 Mira 19, Yekaterinburg, 620002, Russia

    Dmitry S. Kopchuk, Olga S. Taniya, Albert F. Khasanov, Alexey P. Krinochkin, Igor S. Kovalev, Tatiana A. Pospelova, Grigory V. Zyryanov, Vladimir L. Rusinov & Oleg N. Chupakhin

  2. Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22 S. Kovalevskoi / 20 Akademicheskaya St, Yekaterinburg, 620990, Russia

    Dmitry S. Kopchuk, Olga S. Taniya, Albert F. Khasanov, Alexey P. Krinochkin, Grigory V. Zyryanov, Vladimir L. Rusinov & Oleg N. Chupakhin

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  1. Dmitry S. Kopchuk
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  2. Olga S. Taniya
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  3. Albert F. Khasanov
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  4. Alexey P. Krinochkin
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  5. Igor S. Kovalev
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  6. Tatiana A. Pospelova
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  7. Grigory V. Zyryanov
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  8. Vladimir L. Rusinov
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  9. Oleg N. Chupakhin
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Correspondence to Grigory V. Zyryanov.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, 2019, 55(6), 490–504

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Kopchuk, D.S., Taniya, O.S., Khasanov, A.F. et al. СН functionalization of (hetero)arenes with ethyne and ethene moieties. Chem Heterocycl Comp 55, 490–504 (2019). https://doi.org/10.1007/s10593-019-02487-5

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