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High-efficacy antimicrobial cellulose grafted by a novel quaternarized N-halamine

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Abstract

A novel quaternarized N-halamine precursor (3-chloro-2-hydroxypropyl)-(5, 5-dimethylhydantoinyl-1-ylmethyl)-dimethylammonium chloride (CDDAC), has been synthesized by a very facile two-step reaction. The two-step synthesis of CDDAC occurred at room temperature with common reactors, so the production of CDDAC could be easily enlarged to an industrial scale. Without any work-up, the final reaction solution which contained CDDAC could be directly used as grafting solution. CDDAC could be effectively grafted onto the surface of cellulose by a dehydrochlorination reaction. CDDAC grafted on cellulose was converted to N-halamine structure which showed powerful antimicrobial property by a chlorination reaction in the diluted NaClO solution. The antimicrobial tests showed that the chlorinated cellulose grafted with CDDAC was capable of 5-log inactivation of S. aureus and E. coli within 5 min. Also, the washing durability and storage stability of chlorinated cellulose grafted with CDDAC were investigated.

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Acknowledgments

The authors would like to acknowledge the financial support from the Shanghai Natural Science Foundation (10ZR1407700), Shanghai Pujiang Talent Project (11PJ1407600), the Research and Innovation Project of Municipal Education Commission of Shanghai (12YZ085).

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Authors and Affiliations

  1. Key Laboratory of Resource Chemistry of Ministry of Education of China, College of Life and Environmental Science, Shanghai Normal University, No. 100, Guilin Road, Shanghai, 200234, People’s Republic of China

    Zhen-Zhen Kang, Bing Zhang, Yu-Chao Jiao, Ying-Hao Xu, Qi-Zhuang He & Jie Liang

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  1. Zhen-Zhen Kang
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  2. Bing Zhang
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  3. Yu-Chao Jiao
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  4. Ying-Hao Xu
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  5. Qi-Zhuang He
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  6. Jie Liang
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Correspondence to Jie Liang.

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Kang, ZZ., Zhang, B., Jiao, YC. et al. High-efficacy antimicrobial cellulose grafted by a novel quaternarized N-halamine. Cellulose 20, 885–893 (2013). https://doi.org/10.1007/s10570-012-9848-4

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  • DOI: https://doi.org/10.1007/s10570-012-9848-4

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