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Contrast Agents Based on Iron Oxide Nanoparticles for Clinical Magnetic Resonance Imaging

  • BIOTECHNOLOGIES
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Bulletin of Experimental Biology and Medicine Aims and scope

Magnetic resonance imaging (MRI) is one of the most perspective methods of noninvasive visualization in medicine, and use of contrast agents significantly its potentialities extends. Iron oxide nanoparticles are promising contrast agents, but in fact all the data on their efficiency were obtained in high-field tomographs for experimental animals. We studied the possibility of using magnetic nanoparticles for MRI visualization of rat brain glioblastoma at the most common clinical field 1.5 T The data indicate the efficiency of iron oxide magnetic nanoparticles as contrast agents for 1.5 T MR tomographs.

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Authors and Affiliations

  1. N. I. Pirogov Russian Research Medical University, Ministry of Health of the Russian Federation, Moscow, Russia

    M. A. Abakumov & V. P. Chekhonin

  2. Biomedical Nanomaterials Laboratory, National University of Science and Technology MISIS, Moscow, Russia

    M. A. Abakumov & A. G. Mazhuga

  3. National Medical Research Center for Cardiology, Ministry of Health of the Russian Federation, Moscow, Russia

    S. K. Ternovoi

  4. I. M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of the Russian Federation, Moscow, Russia

    S. K. Ternovoi

  5. P. N. Lebedev Physical Institute, Russian Academy of Sciences, Moskva, Russia

    E. I. Demikhov, A. G. Pistrak, M. V. Konstantinov & D. M. Dmitriev

  6. Faculty of Chemistry, M. V. Lomonosov Moscow State University, Moscow, Russia

    A. G. Mazhuga

  7. D. I. Mendeleev Russian Chemical Technological University, Moscow, Russia

    A. G. Mazhuga

  8. Gelpik Company, Moscow, Russia

    B. Ya. Myshkinis

Authors
  1. M. A. Abakumov
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  2. S. K. Ternovoi
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  3. A. G. Mazhuga
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  4. V. P. Chekhonin
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  5. E. I. Demikhov
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  6. A. G. Pistrak
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  7. M. V. Konstantinov
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  8. D. M. Dmitriev
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  9. B. Ya. Myshkinis
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Corresponding author

Correspondence to M. A. Abakumov.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 167, No. 2, pp. 233-235, February, 2019

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Abakumov, M.A., Ternovoi, S.K., Mazhuga, A.G. et al. Contrast Agents Based on Iron Oxide Nanoparticles for Clinical Magnetic Resonance Imaging. Bull Exp Biol Med 167, 272–274 (2019). https://doi.org/10.1007/s10517-019-04507-y

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  • DOI: https://doi.org/10.1007/s10517-019-04507-y

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