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Bacteriophages for aquaculture disease control

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Abstract

The administration of phage therapy for aquaculture disease has been anticipated by the researchers over a decade as an effective and an alternative control mechanism, though the application of phages as a disease control agent in aquaculture projects various beneficial aspects, critical limitations, and negative influence on production. This present scenario made a pressure to review the possible disclosure of phage therapy with its critical boundaries and limiting influences towards the disease control management of aquaculture (fish, shrimps, lobsters, bivalve mollusks, etc.). The phage therapy has proven its efficacy as a biocontrol agent towards aquaculture disease, although the sustainability of the phage therapy needs further investigation on the following: commercial application, formulation of bacteriophage for layman usage, and development of protocol for various diseases with consistent results. The marginal space existing between the inventors and the end user must be fulfilled by the awareness program and the government policies. The administration of the phage therapy could be effective for long-term safety and negatively influence the development of multidrug-resistant bacteria pathogens in the future.

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The University Grants Commission, New Delhi, provided research grant and support to SS and PR. GSK received research grant from DBT.

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Authors and Affiliations

  1. Department of Biotechnology, Block-II CGO Complex, Lodhi Road, New Delhi, 110003, India

    A. S. Ninawe

  2. Department of Microbiology, School of Life Sciences, Pondicherry University, Puducherry, 605014, India

    S. Sivasankari, P. Ramasamy & Joseph Selvin

  3. Department of Food Science and Technology, School of Life Sciences, Pondicherry University, Puducherry, 605014, India

    G. Seghal Kiran

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  1. A. S. Ninawe
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  2. S. Sivasankari
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  4. G. Seghal Kiran
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Correspondence to Joseph Selvin.

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Ninawe, A.S., Sivasankari, S., Ramasamy, P. et al. Bacteriophages for aquaculture disease control. Aquacult Int 28, 1925–1938 (2020). https://doi.org/10.1007/s10499-020-00567-4

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