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The roles of autophagy in development and stress responses in Arabidopsis thaliana

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Abstract

Autophagy is a dynamic process that involves the recycling process of the degradation of intracellular materials. Over the past decade, our molecular and physiological understanding of plant autophagy has greatly been increased. Most essential autophagic machineries are conserved from yeast to plants. The roles that autophagy-related genes (ATGs) family play in the lifecycle of the Arabidopsis are proved to be similar to that in mammal. Autophagy is activated during certain stages of development, senescence or in response to starvation, or environmental stress in Arabidopsis. In the progression of autophagy, ATGs act as central signaling regulators and could develop sophisticated mechanisms to survive when plants are suffering unfavorable environments. It will facilitate further understanding of the molecular mechanisms of autophagy in plant. In this review, we will discuss recent advances in our understanding of autophagy in Arabidopsis, areas of controversy, and highlight potential future directions in autophagy research.

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Abbreviations

ACBP3:

Acyl-CoA-binding protein

Atg:

Autophagy-related gene

CMA:

Chaperon-mediated-autophagy

HR:

Hypersensitive response

3-MA:

3-Methyladenine

PAS:

Pre-autophagosomal structure

PCD:

Programmed cell death

PE:

Phosphatidylethanolamine

PI3P:

Phosphatidyl-inositol-3 phosphate

PKA:

Protein kinase A

RCB:

Rubisco-containing bodies

ROS:

Reactive oxygen species

SNF:

Sucrose non-fermenting

TOR:

Target of rapamycin

TSPO:

Tryptophan-rich sensory protein-related

VPS:

Vacuolar protein sorting

PO:

Peroxisomes

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Acknowledgments

We thank Prof. Jinku Bao (Sichuan University) and Zhi Shi (Sichuan University) for their useful suggestions. This work was supported by the National Nature Science Foundation of China (91017004) and Doctoral Foundation of the Ministry of Education (20110181110059 and 20120181130008).

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  1. Key Laboratory of Bio-resources & Eco-environment (Ministry of Education), College of Life Science, Sichuan University, Chengdu, 610064, China

    Xin Lv, Xiaojun Pu, Gongwei Qin, Tong Zhu & Honghui Lin

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  1. Xin Lv
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  2. Xiaojun Pu
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  3. Gongwei Qin
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  4. Tong Zhu
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  5. Honghui Lin
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Correspondence to Honghui Lin.

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Lv, X., Pu, X., Qin, G. et al. The roles of autophagy in development and stress responses in Arabidopsis thaliana . Apoptosis 19, 905–921 (2014). https://doi.org/10.1007/s10495-014-0981-4

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