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Bildgebung bei neuroendokrinen Tumoren

Ultraschall-, CT- und MRT-Diagnostik

Imaging techniques for neuroendocrine tumors

Ultrasonography, computed tomography, and magnetic resonance imaging

  • Leitthema: endokrine Tumoren
  • Published:
Der Onkologe Aims and scope

Zusammenfassung

Zielsetzung

Darstellung der Wertigkeit der Bild gebenden Verfahren für die Diagnostik von neuroendokrinen Tumoren (NET) des gastroenteropankreatischen Systems.

Methodik

Analyse des Stellenwerts von Ultraschall (US), Computertomographie (CT) und Magnetresonanztomographie (MRT) unter Berücksichtigung diagnostischer Strategien und Ergebnisse der Literatur.

Ergebnisse

Für die Primärtumor- und Ausbreitungsdiagnostik wurden in Abhängigkeit der Lokalisation Sensitivitäten für den US von ca. 60%, den EUS von über 90% beschrieben. Die MRT weist für die Pankreasdiagnostik eine gegenüber der CT höhere Sensitivität (75–100% vs. 72–82%) auf und ist im Nachweis einer Lebermetastasierung führend. Einschränkungen bestehen in der Diagnostik von NET des Darmtrakts. Insbesondere zur Primärtumorsuche sind hier die Somatostatinrezeptorszintigraphie und endoskopische Verfahren als vorrangig zu betrachten.

Schlussfolgerung

Eine suffiziente Diagnostik von NET bedarf der Kombination aus radiologischen, nuklearmedizinischen und endoskopischen Verfahren.

Abstract

Objective

Comparison of the diagnostic value of imaging modalities in the detection of gastroenteropancreatic neuroendocrine tumors (NET).

Methods

Analysis of the value of ultrasound, computed tomography (CT), magnetic resonance imaging (MRI), and diagnostic strategies according to the current literature.

Results

Depending on the localization of primaries and metastases, a sensitivity of 60% and 90% is described for US and EUS, respectively. Concerning pancreatic lesions and liver metastases, MRI is more sensitive than CT (75–100% vs 72–82%). Concerning lesions of the bowel, these modalities are subject to limitations. In this field somatostatin receptor scintigraphy and endoscopic procedures are superior.

Conclusion

A sufficient diagnostic strategy for NET often requires a combination of various imaging modalities.

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Authors and Affiliations

  1. Klinik für Strahlenheilkunde, Campus Virchow-Klinikum, Charité—Universitätsmedizin Berlin

    H. Amthauer, J. Ruf & J. Ricke

  2. II. Medizinische Klinik, Klinikum rechts der Isar, Technische Universität München

    T. Rösch

  3. Klinik für Strahlenheilkunde, Campus Virchow-Klinikum, Charité—Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin

    H. Amthauer

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  1. H. Amthauer
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Correspondence to H. Amthauer.

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Amthauer, H., Ruf, J., Rösch, T. et al. Bildgebung bei neuroendokrinen Tumoren. Onkologe 10, 588–597 (2004). https://doi.org/10.1007/s00761-004-0717-0

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