Skip to main content

Advertisement

Log in

Delayed gastric emptying improved by straight stomach reconstruction with twisted anastomosis to the jejunum after pylorus-preserving pancreaticoduodenectomy (PPPD) in 118 consecutive patients at a single institution

  • Original Article
  • Published:
Surgery Today Aims and scope Submit manuscript

Abstract

Purpose

Delayed gastric emptying (DGE) is a leading cause of complication after pylorus-preserving pancreaticoduodenectomy (PPPD). Its incidence has been reported to range from 5 to 57%. We describe a modified reconstruction method, which resulted in a low rate of DGE.

Methods

Between April 2003 and March 2008, we performed PPPD and reconstruction using an antecolic method in 118 consecutive patients. After PPPD, reconstruction was done using conventional Child procedure in 12 patients (PPPD group) and with the following modifications in the remaining 106 patients (PPPDR group): duodenojejunostomy was performed using the straight method and the jejunum was anastomosed with a 30° counterclockwise twist. We evaluated the incidence of DGE based on the grading system defined by the International Study Group of Pancreatic Surgery (ISGPS).

Results

The PPPDR group had a lower incidence of DGE than the PPPD group (PPPD), occurring in 7 patients (7%) versus 4 patients (33%), respectively. However, the overall morbidity rates and postoperative hospital stays of the two groups did not differ significantly.

Conclusions

Straight stomach reconstruction with a twisted anastomosis could reduce the incidence of DGE after PPPD reconstruction.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Bassi C, Falconi M, Salvia R, Mascetta G, Molinari E, Pederzoli P. Management of complications after pancreaticoduodenectomy in a high volume centre: results on 150 consecutive patients. Dig Surg. 2001;18(6):453–7. (discussion 458).

    Google Scholar 

  2. Butturini G, Marcucci S, Molinari E, Mascella G, Landoni L, Crippa S, et al. Complications after pancreaticoduodenectomy: the problem of current definitions. J Hepatobiliary Pancreat Surg. 2006;13(3):207–11.

    Article  PubMed  Google Scholar 

  3. Trede M, Schwall G. The complications of pancreatectomy. Ann Surg. 1988;207(1):39–47.

    Article  PubMed  CAS  Google Scholar 

  4. Wagner M, Redaelli C, Lietz M, Seiler CA, Friess H, Buchler MW. Curative resection is the single most important factor determining outcome in patients with pancreatic adenocarcinoma. Br J Surg. 2004;91(5):586–94.

    Article  PubMed  CAS  Google Scholar 

  5. Horstmann O, Markus PM, Ghadimi MB, Becker H. Pylorus preservation has no impact on delayed gastric emptying after pancreatic head resection. Pancreas. 2004;28(1):69–74.

    Article  PubMed  Google Scholar 

  6. Traverso LW, Longmire WP Jr. Preservation of the pylorus in pancreaticoduodenectomy a follow-up evaluation. Ann Surg. 1980;192(3):306–10.

    Article  PubMed  CAS  Google Scholar 

  7. Grace PA, Pitt HA, Longmire WP. Pylorus preserving pancreatoduodenectomy: an overview. Br J Surg. 1990;77(9):968–74.

    Article  PubMed  CAS  Google Scholar 

  8. Yeo CJ, Cameron JL, Sohn TA, Lillemoe KD, Pitt HA, Talamini MA, et al. Six hundred fifty consecutive pancreaticoduodenectomies in the 1990s: pathology, complications, and outcomes. Ann Surg. 1997;226(3):248–57. (discussion 257–260).

    Google Scholar 

  9. Zerbi A, Balzano G, Patuzzo R, Calori G, Braga M, Di Carlo V. Comparison between pylorus-preserving and Whipple pancreatoduodenectomy. Br J Surg. 1995;82(7):975–9.

    Article  PubMed  CAS  Google Scholar 

  10. Kozuschek W, Reith HB, Waleczek H, Haarmann W, Edelmann M, Sonntag D. A comparison of long term results of the standard Whipple procedure and the pylorus preserving pancreatoduodenectomy. J Am Coll Surg. 1994;178(5):443–53.

    PubMed  CAS  Google Scholar 

  11. Cameron JL, Pitt HA, Yeo CJ, Lillemoe KD, Kaufman HS, Coleman J. One hundred and forty-five consecutive pancreaticoduodenectomies without mortality. Ann Surg. 1993;217(5):430–5. (discussion 435–438).

    Google Scholar 

  12. Yamaguchi K, Tanaka M, Chijiiwa K, Nagakawa T, Imamura M, Takada T. Early and late complications of pylorus-preserving pancreatoduodenectomy in Japan 1998. J Hepatobiliary Pancreat Surg. 1999;6(3):303–11.

    Article  PubMed  CAS  Google Scholar 

  13. Wente MN, Shrikhande SV, Kleeff J, Muller MW, Gutt CN, Buchler MW, et al. Management of early hemorrhage from pancreatic anastomoses after pancreaticoduodenectomy. Dig Surg. 2006;23(4):203–8.

    Article  PubMed  Google Scholar 

  14. Traverso LW, Shinchi H, Low DE. Useful benchmarks to evaluate outcomes after esophagectomy and pancreaticoduodenectomy. Am J Surg. 2004;187(5):604–8.

    Article  PubMed  Google Scholar 

  15. Tanaka M, Sarr MG. Effects of exogenous motilin and morphine on interdigestive gastrointestinal motor activity after total duodenectomy in dogs. Surgery. 1988;104(2):317–25.

    PubMed  CAS  Google Scholar 

  16. Matsunaga H, Tanaka M, Naritomi G, Yokohata K, Yamaguchi K, Chijiwa K. Effect of leucine 13-motilin (KW5139) on early gastric stasis after pylorus-preserving pancreatoduodenectomy. Ann Surg. 1998;227(4):507–12.

    Article  PubMed  CAS  Google Scholar 

  17. Kim DK, Hindenburg AA, Sharma SK, Suk CH, Gress FG, Staszewski H, et al. Is pylorospasm a cause of delayed gastric emptying after pylorus-preserving pancreaticoduodenectomy? Ann Surg Oncol. 2005;12(3):222–7.

    Article  PubMed  Google Scholar 

  18. Gauvin JM, Sarmiento JM, Sarr MG. Pylorus-preserving pancreaticoduodenectomy with complete preservation of the pyloroduodenal blood supply and innervation. Arch Surg. 2003;138(11):1261–3.

    Article  PubMed  Google Scholar 

  19. Riediger H, Makowiec F, Schareck WD, Hopt UT, Adam U. Delayed gastric emptying after pylorus-preserving pancreatoduodenectomy is strongly related to other postoperative complications. J Gastrointest Surg. 2003;7(6):758–65.

    Article  PubMed  Google Scholar 

  20. Tani M, Terasawa H, Kawai M, Ina S, Hirono S, Uchiyama K, et al. Improvement of delayed gastric emptying in pylorus-preserving pancreaticoduodenectomy: results of a prospective, randomized, controlled trial. Ann Surg. 2006;243(3):316–20.

    Article  PubMed  Google Scholar 

  21. Martignoni ME, Friess H, Sell F, Ricken L, Shrikhande S, Kulli C, et al. Enteral nutrition prolongs delayed gastric emptying in patients after Whipple resection. Am J Surg. 2000;180(1):18–23.

    Article  PubMed  CAS  Google Scholar 

  22. Kurosaki I, Hatakeyama K. Clinical and surgical factors influencing delayed gastric emptying after pyloric-preserving pancreaticoduodenectomy. Hepatogastroenterology. 2005;52(61):143–8.

    PubMed  Google Scholar 

  23. Wente MN, Bassi C, Dervenis C, Fingerhut A, Gouma DJ, Izbicki JR, et al. Delayed gastric emptying (DGE) after pancreatic surgery: a suggested definition by the International Study Group of Pancreatic Surgery (ISGPS). Surgery. 2007;142(5):761–8.

    Article  PubMed  Google Scholar 

  24. Ueno T, Takashima M, Iida M, Yoshida S, Suzuki N, Oka M. Improvement of early delayed gastric emptying in patients with Billroth I type of reconstruction after pylorus preserving pancreatoduodenectomy. J Hepatobiliary Pancreat Surg. 2009;16(3):300–4.

    Article  PubMed  Google Scholar 

  25. Seiler CA, Wagner M, Sadowski C, Kulli C, Buchler MW. Randomized prospective trial of pylorus-preserving vs. classic duodenopancreatectomy (Whipple procedure): initial clinical results. J Gastrointest Surg. 2000;4(5):443–52.

    Article  PubMed  CAS  Google Scholar 

  26. Niedergethmann M, Shang E, Farag Soliman M, Saar J, Berisha S, Willeke F, et al. Early and enduring nutritional and functional results of pylorus preservation vs classic Whipple procedure for pancreatic cancer. Langenbecks Arch Surg. 2006;391(3):195–202.

    Article  PubMed  Google Scholar 

  27. Buchler MW, Wagner M, Schmied BM, Uhl W, Friess H, Z’Graggen K. Changes in morbidity after pancreatic resection: toward the end of completion pancreatectomy. Arch Surg. 2003;138(12):1310–14. (discussion 1315).

    Google Scholar 

  28. Tani M, Kawai M, Hirono S, Ina S, Miyazawa M, Fujita Y, et al. Pylorus-preserving pancreaticoduodenectomy versus conventional pancreaticoduodenectomy for pancreatic adenocarcinoma. Surg Today. 2009;39(3):219–24.

    Article  PubMed  Google Scholar 

  29. Sugiyama M, Abe N, Ueki H, Masaki T, Mori T, Atomi Y. A new reconstruction method for preventing delayed gastric emptying after pylorus-preserving pancreatoduodenectomy. Am J Surg. 2004;187(6):743–6.

    Article  PubMed  Google Scholar 

Download references

Conflict of interest

Toshihiko Masui and his co-authors have no conflict of interest to declare.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Toshihiko Masui.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Masui, T., Doi, R., Kawaguchi, Y. et al. Delayed gastric emptying improved by straight stomach reconstruction with twisted anastomosis to the jejunum after pylorus-preserving pancreaticoduodenectomy (PPPD) in 118 consecutive patients at a single institution. Surg Today 42, 441–446 (2012). https://doi.org/10.1007/s00595-011-0097-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00595-011-0097-1

Keywords

Navigation