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Tunneled hemodialysis catheter care practices and blood stream infection rate in children: results from the SCOPE collaborative

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Abstract

Objective

The Standardizing Care to Improve Outcomes in Pediatric End Stage Renal Disease (SCOPE) collaborative seeks to reduce hemodialysis (HD) catheter-associated blood stream infections (CA-BSI) by increasing implementation of standardized HD catheter care bundles. We report HD catheter care practices and HD CA-BSI rates from SCOPE.

Methods

Catheter care practices and infection events were collected prospectively during the study period, from collaborative implementation in June 2013 through May 2017. For comparative purposes, historical data, including patient demographics and HD CA-BSI events, were collected from the 12 months prior to implementation. Catheter care bundle compliance in 5 care bundle categories was monitored across the post-implementation reporting period at each center via monthly care observation forms. CA-BSI rates were calculated monthly, and reported as number of infections per 100 patient months. Changes in CA-BSI rates were assessed using generalized linear mixed model (GLMM) techniques.

Results

Three hundred twenty-five patients with tunneled HD catheters [median (IQR) age 12 years (6, 16), M 53%, F 47%] at 15 centers were included. A total of 3996 catheter care observations over 4170 patient months were submitted with a median (IQR) 5 (2, 14) observations per patient. Overall bundle compliance was high at 87.6%, with a significant and progressive increase (p < 0.001) in compliance for 4/5 bundle categories over the 48-month study period. The adjusted CA-BSI rate significantly decreased over time from 3.3/100 patient months prior to implementation of the care bundles to 0.8/100 patient months 48 months after care bundle implementation (p < 0.001).

Conclusions

Using quality improvement methodology, SCOPE has demonstrated a significant increase in compliance with a majority of HD catheter care practices and a significant reduction in the rate of CA-BSI among children maintained on HD.

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Acknowledgment

SCOPE partners with the CDC’s Making Dialysis Safer for Patients Coalition.

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Authors and Affiliations

  1. Pediatric Nephrology, Yale University School of Medicine, 333 Cedar Street, New Haven, CT, 06510, USA

    Olivera Marsenic

  2. The Children’s Hospital Association, Lenexa, KS, USA

    Jonathan Rodean & Troy Richardson

  3. Texas Children’s Hospital, Houston, TX, USA

    Sarah Swartz

  4. Cincinnati Children’s Hospital, Cincinnati, OH, USA

    Donna Claes

  5. Children’s Mercy Kansas City, Kansas City, MO, USA

    J. Christopher Day & Bradley Warady

  6. Johns Hopkins University School of Medicine, Baltimore, MD, USA

    Alicia Neu

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  1. Olivera Marsenic
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  8. Alicia Neu
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on behalf of the Standardizing Care to Improve Outcomes in Pediatric End Stage Renal Disease (SCOPE) Investigators

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Correspondence to Olivera Marsenic.

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Marsenic, O., Rodean, J., Richardson, T. et al. Tunneled hemodialysis catheter care practices and blood stream infection rate in children: results from the SCOPE collaborative. Pediatr Nephrol 35, 135–143 (2020). https://doi.org/10.1007/s00467-019-04384-7

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  • DOI: https://doi.org/10.1007/s00467-019-04384-7

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