Abstract
Swallowing disorders are a common complaint among the elderly. Recently, surface electrical stimulation applied to the neck region has received increased attention as a new modality to treat pharyngeal dysphagia. Previous reports used pulsed current at a frequency range of 1-120 Hz. Kilohertz-frequency alternating currents (ACs) have not been tested for treating dysphagia. Therefore, we evaluated the effects of interferential currents (IFCs), the most popular modality of amplitude-modulated kilohertz-frequency ACs in clinical practice, on the swallowing reflex in healthy subjects. We found that IFC stimulation at the sensory threshold with 50-Hz modulation significantly increased the number of swallows without any discomfort, but pure AC stimulation at the carrier frequency did not have a significant effect. There was no statistically significant difference in the time course of the number of swallows among 1,000-, 2,000-, 4,000-, and 6,000-Hz carrier frequencies. The number of swallows remained increased during the 15-min IFC stimulation, suggesting that IFC stimulation facilitates the swallowing reflex without adaptation, at least during this stimulation period. We suggest that an IFC stimulation or a low-frequency, modulated kilohertz AC stimulation, which would be more comfortable than pulsed currents, is an alternative stimulation mode for treating pharyngeal dysphagia.
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References
Shamburek RD, Farrar JT. Disorders of the digestive system in the elderly. N Engl J Med. 1990;322:438–43.
Martino R, Foley N, Bhogal S, Diamant N, Speechley M, Teasell R. Dysphagia after stroke: incidence, diagnosis, and pulmonary complications. Stroke. 2005;36:2756–63.
Byrne K, Pfeiffer R, Quigley E. Gastrointestinal dysfunction in Parkinson’s disease: a report of clinical experience at a single center. J Clin Gastroenterol. 1994;19:11–6.
Freed ML, Freed L, Chatburn RL, Christian M. Electrical stimulation for swallowing disorders caused by stroke. Respir Care. 2001;46:466–74.
Bulow M, Speyer R, Baijens L, Woisard V, Ekberg O. Neuromuscular electrical stimulation (NMES) in stroke patients with oral and pharyngeal dysfunction. Dysphagia. 2008;23:302–9.
Ludlow CL, Humbert I, Saxon K, Poletto C, Sonies B, Crujido L. Effects of surface electrical stimulation both at rest and during swallowing in chronic pharyngeal dysphagia. Dysphagia. 2007;22:1–10.
Carnaby-Mann GD, Crary MA. Examining the evidence on neuromuscular electrical stimulation for swallowing—a meta-analysis. Arch Otolaryngol Head Neck Surg. 2007;133:564–71.
Ward AR. Electrical stimulation using kilohertz-frequency alternating current. Phys Ther. 2009;89:181–90.
Palmer ST, Martin DJ, Steedman WM, Ravey J. Alteration of interferential current and transcutaneous electrical nerve stimulation frequency: effects on nerve excitation. Arch Phys Med Rehabil. 1999;80:1065–71.
Cohen J. Statistical power analysis for the behavioral sciences. 2nd ed. Hillsdale, NJ: Lawrence Erlbaum; 1988.
Alon G, Allin J, Inbar GF. Optimization of pulse duration and pulse charge during transcutaneous electrical nerve stimulation. Aust J Physiother. 1983;29:195–201.
Ward AR, Robertson VJ. Sensory, motor, and pain thresholds for stimulation with medium frequency alternating current. Arch Phys Med Rehabil. 1998;79:273–8.
Jean A. Brain stem control of breathing: neuronal network and cellular mechanisms. Physiol Rev. 2001;81:929–69.
Oku Y, Tanaka I, Ezure K. Activity of bulbar respiratory neurons during fictive coughing and swallowing in the decerebrate cat. J Physiol Lond. 1994;480:309–24.
Kitagawa J, Nakagawa K, Hasegawa M, Iwakami T, Shingai T, Yamada Y, Iwata K. Facilitation of reflex swallowing from the pharynx and larynx. J Oral Sci. 2009;51:167–71.
Miller AJ, Lozzi RF. Anatomical and functional differentiation of superior laryngeal nerve fibers affecting swallowing and respiration. Exp Neurol. 1974;42:369–87.
Saito Y, Ezure K, Tanaka I. Difference between hypoglossal and phrenic activities during lung inflation and swallowing in the rat. J Physiol Lond. 2002;544:183–93.
Koga K, Furue H, Rashid MH, Takaki A, Katafuchi T, Yoshimura M. Selective activation of primary afferent fibers evaluated by sine-wave electrical stimulation. Mol Pain. 2005;1:13.
Ikari T, Sasaki CT. Glottic closure reflex: control mechanisms. Ann Otol. 1980;89:220–4.
Nemec H. Interferential therapy: a new approach in physical medicine. Br J Physiother. 1959;12:9–12.
Robertson VJ, Ward AR, Low J, Reed A. Electrotherapy explained. Principles and practice. 4th ed. Oxford, UK: Butterworth Heinemann; 2006.
Park CL, ONeill PA, Martin DF. A pilot exploratory study of oral electrical stimulation on swallow function following stroke: an innovative technique. Dysphagia. 1997;12:161–6.
Power M, Fraser C, Hobson A, Rothwell JC, Mistry S, Nicholson DA, Thompson DG, Hamdy S. Changes in pharyngeal corticobulbar excitability and swallowing behavior after oral stimulation. Am J Physiol Gastrointest Liver Physiol. 2004;286:G45–50.
Köklü S, Köklü G, Özgüçlü E, Kayani G, Akbal E, Hasçelik Z. Clinical trial: interferential electric stimulation in functional dyspepsia patients—a prospective randomized study. Aliment Pharmacol Ther. 2010;31:961–8.
Acknowledgments
The authors thank Prof. Y. Muraoka and Dr. T. Daimon, Department of Mathematics, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan, for their valuable comments on statistical methods.
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Furuta, T., Takemura, M., Tsujita, J. et al. Interferential Electric Stimulation Applied to the Neck Increases Swallowing Frequency. Dysphagia 27, 94–100 (2012). https://doi.org/10.1007/s00455-011-9344-2
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DOI: https://doi.org/10.1007/s00455-011-9344-2