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Characteristics of cases with postoperative vitreous hemorrhage after 25-gauge vitrectomy for repair of proliferative diabetic retinopathy

  • Retinal Disorders
  • Published:
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Abstract

Purpose

The purpose of this study was to compare ocular and systemic parameters between proliferative diabetic retinopathy (PDR) cases with postoperative vitreous hemorrhage (PVH) and those without PVH after 25-gauge vitrectomy, and to investigate the predictors of PVH.

Methods

The medical records of 106 eyes of 78 consecutive patients who underwent primary 25-gauge vitrectomy were reviewed.

Results

The incidences of early and late PVH were found to be 18.9 % (20/106 eyes) and 17.9 % (19/106 eyes) respectively. On multiple logistic regression analysis, intraoperative bleeding from new vessels on the disc was identified as the most important factor, with the greatest odds ratio, for the development of early PVH (odds ratio = 3.395, P = 0.134), while the HbA1c level was identified as the most important significant factor, with the greatest odds ratio, for the development of late PVH (odds ratio = 1.403, P = 0.014).

Conclusions

Early PVH tends to occur in severe PDR cases, while late PVH tends to occur in cases with poor diabetic control.

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Authors and Affiliations

  1. Osaka Rosai Hospital Clinical Research Center for Occupational Sensory Organ Disability, Sakai, Japan

    Tatsuhiko Sato, Kotaro Tsuboi, Hiroshi Nakashima & Kazuyuki Emi

  2. Department of Ophthalmology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan

    Tatsuhiko Sato

Authors
  1. Tatsuhiko Sato
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  2. Kotaro Tsuboi
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  3. Hiroshi Nakashima
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  4. Kazuyuki Emi
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Corresponding author

Correspondence to Tatsuhiko Sato.

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Funding

This study was supported by the Clinical Research Center for Occupational Sensory Organ Disability of the Ministry of Health, Labour and Welfare, Tokyo, Japan. The funding organization had no role in the design or conduct of this research.

Conflict of interest

All authors certify that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria; educational grants; participation in speakers’ bureaus; membership, employment, consultancies, stock ownership, or other equity interest; and expert testimony or patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge, or beliefs) in the subject matter or materials discussed in this manuscript.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Sato, T., Tsuboi, K., Nakashima, H. et al. Characteristics of cases with postoperative vitreous hemorrhage after 25-gauge vitrectomy for repair of proliferative diabetic retinopathy. Graefes Arch Clin Exp Ophthalmol 255, 665–671 (2017). https://doi.org/10.1007/s00417-016-3522-8

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  • DOI: https://doi.org/10.1007/s00417-016-3522-8

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