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Diagnosis of bladder cancer: contrast-enhanced ultrasound

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Abstract

Contrast-enhanced ultrasound imaging represents a new approach to imaging tumoral neovascularity. This review describes the application of contrast-enhanced ultrasound in the detection, differential diagnosis, and staging of bladder cancer.

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References

  1. Greenlee RT, Hill-Harmon MB, Murray T, Thun M.Cancer statistics, 2001.CA Cancer J Clin. 2001; 51(1):15–36.

    Article  CAS  PubMed  Google Scholar 

  2. Kirkali Z, Chan T, Manoharan M, et al. Bladder cancer: epidemiology, staging and grading, and diagnosis. Urology 2005;66 (6 Suppl 1):4–34.

    Article  PubMed  Google Scholar 

  3. Berlac PA, Holm HH. Bladder tumor control by abdominal ultrasound and urine cytology. J Urol. 1992;147(6):1510–2.

    CAS  PubMed  Google Scholar 

  4. Dibb MJ, Noble DJ, Peh WC, Lam CH, Yip KH, Li JH, Tam PC. Ultrasonographic analysis of bladder tumors. Clin Imaging. 2001;25(6):416–20.

    Article  CAS  PubMed  Google Scholar 

  5. Vallancien G, Veillon B, Charton M, Brisset JM. Can transabdominal ultrasonography of the bladder replace cystoscopy in the follow up of superficial bladder tumors? J Urol. 1986 Jul;136(1):32–4.

    CAS  PubMed  Google Scholar 

  6. Kocakoc E, Kiris A, Orhan I, et al. Detection of bladder tumors with 3-dimensional sonography and virtual sonographic cystoscopy. J Ultrasound Med. 2008 Jan;27(1):45–53.

    PubMed  Google Scholar 

  7. Francica G, Bellini SA, Scarano F, et al. Correlation of transabdominal sonographic and cystoscopic findings in the diagnosis of focal abnormalities of the urinary bladder wall: a prospective study. J Ultrasound Med. 2008; 27(6):887–94.

    PubMed  Google Scholar 

  8. Lopes RI, Nogueira L, Albertotti CJ, Takahashi DY, Lopes RN. Comparison of virtual cystoscopy and transabdominal ultrasonography with conventional cystoscopy for bladder tumor detection. J Endourol. 2008;22(8):1725–9.

    Article  PubMed  Google Scholar 

  9. Mitterberger M, Pinggera GM, Neuwirt H, et al. Three-dimensional ultrasonography of the urinary bladder: preliminary experience of assessment in patients with haematuria. BJU Int. 2007;99(1):111–6.

    Article  PubMed  Google Scholar 

  10. Song JH, Francis IR, Platt JF, et al. Bladder tumor detection at virtual cystoscopy. Radiology 2001;218(1):95–100.

    CAS  PubMed  Google Scholar 

  11. Beer A, Saar B, Zantl N, et al. MR cystography for bladder tumor detection. Eur Radiol. 2004; 14(12):2311–9.

    Article  PubMed  Google Scholar 

  12. Tsampoulas C, Tsili AC, Giannakis D, et al. 16-MDCT cystoscopy in the evaluation of neoplasms of the urinary bladder.AJR Am J Roentgenol. 2008 Mar;190(3):729–35.

    Article  PubMed  Google Scholar 

  13. Sadow CA, Silverman SG, O′Leary MP, Signorovitch JE. Bladder cancer detection with CT urography in an academic medical center. Radiology 2008; 249: 195–202.

    Article  PubMed  Google Scholar 

  14. Abou-El-Ghar ME, El-Assmy A, Refaie HF, El-Diasty T (2009) Bladder Cancer: diagnosis with diffusion-weighted mr imaging in patients with gross hematuria. Radiology. [Epub ahead of print]

  15. Wang LJ, Wong YC, Chuang CK, Huang CC, Pang ST. Diagnostic accuracy of transitional cell carcinoma on multidetector computerized tomography urography in patients with gross hematuria. J Urol. 2009;181(2):524-31.

    Article  PubMed  Google Scholar 

  16. Park SB, Kim JK, Lee HJ, Choi HJ, Cho KS. Hematuria: portal venous phase multi detector row CT of the bladder–a prospective study. Radiology. 2007;245(3):798–805.

    Article  PubMed  Google Scholar 

  17. Jinzaki M, Tanimoto A, Shinmoto H, et al. Detection of bladder tumors with dynamic contrast-enhanced MDCT. AJR Am J Roentgenol. 2007;188(4):913–8.

    Article  PubMed  Google Scholar 

  18. Tuncbilek N, Kaplan M, Altaner S, et al. Value of dynamic contrast-enhanced MRI and correlation with tumor angiogenesis in bladder cancer. AJR Am J Roentgenol. 2009;192(4):949–55.

    Article  PubMed  Google Scholar 

  19. Barentsz JO, Jager GJ, Witjes JA, Ruijs JH.Primary staging of urinary bladder carcinoma: the role of MRI and a comparison with CT. Eur Radiol. 1996;6(2):129–33.

    Article  CAS  PubMed  Google Scholar 

  20. Kim JK, Park SY, Ahn HJ, Kim CS, Cho KS. Bladder cancer: analysis of multi-detector row helical CT enhancement pattern and accuracy in tumor detection and perivesical staging. Radiology 2004;231(3):725–31.

    Article  PubMed  Google Scholar 

  21. Burns PN, Wilson SR, Simpson DH. Pulse inversion imaging of liver blood flow: improved method for characterizing focal masses with microbubble contrast. Invest Radiol. 2000; 35(1):58–71.

    Article  CAS  PubMed  Google Scholar 

  22. Cosgrove D. Ultrasound contrast agents: an overview. Eur J Radiol. 2006;60(3):324–30.

    Article  PubMed  Google Scholar 

  23. Nicolau C, Brú C. Focal liver lesions: evaluation with contrast-enhanced ultrasonography. Abdom Imaging. 2004;29(3):348–59.

    Article  CAS  PubMed  Google Scholar 

  24. Lencioni R, Della Pina C, Crocetti L, Bozzi E, Cioni D. Clinical management of focal liver lesions: the key role of real-time contrast-enhanced US.. Eur Radiol. 2007;17 Suppl 6:F73–9.

    PubMed  Google Scholar 

  25. D’Onofrio M, Zamboni G, Faccioli N, Capelli P, Pozzi Mucelli R. Ultrasonography of the pancreas. 4. Contrast-enhanced imaging. Abdom Imaging. 2007;32(2):171–81.

    Article  PubMed  Google Scholar 

  26. Claudon M, Cosgrove D, Albrecht T, et al. Guidelines and good clinical practice recommendations for contrast enhanced ultrasound (CEUS)—update 2008. Ultraschall Med. 2008;29(1):28–44.

    Article  CAS  PubMed  Google Scholar 

  27. Salvaggio G, Caruso G, Campisi A, et al. (2008) Contrast-enhanced ultrasound in the evaluation of bladder neoplasms: preliminary results [abstract]. RSNA 94th scientific assembly and annual meeting 2008, p 866

  28. Cantisani V, Marchetti F, Lombardi V, et al. (2008) Low mechanical index CEUS and contrast-enhanced MRI in the differentiation of urinary bladder lesions [abstract]. RSNA 94th scientific assembly and annual meeting 2008, p 866

  29. Saksena MA, Dahl DM, Harisinghani MG. New imaging modalities in bladder cancer. World J Urol. 2006;24(5):473–80.

    Article  PubMed  Google Scholar 

  30. Nicolau C, Bunesch L, Salvador R, et al. (2008) Contrast-enhanced ultrasound accuracy in the detection of bladder tumor in patients with hematuria [abstract]. RSNA 94th scientific assembly and annual meeting 2008, p 575

  31. Kim B, Semelka RC, Ascher SM et al. Bladder tumor staging: comparison of contrast-enhanced CT, T1- and T2-weighted MR imaging, dynamic gadolinium-enhanced imaging, and late gadolinium-enhanced imaging. Radiology 1994;193(1):239–45.

    CAS  PubMed  Google Scholar 

  32. Tekes A, Kamel I, Imam K, et al. Dynamic MRI of bladder cancer: evaluation of staging accuracy. AJR Am J Roentgenol. 2005;184(1):121–7.

    PubMed  Google Scholar 

  33. Takeuchi M, Sasaki S, Ito M, et al. Urinary bladder cancer: diffusion-weighted MR imaging–accuracy for diagnosing T stage and estimating histologic grade. Radiology 2009;251(1):112–21.

    Article  PubMed  Google Scholar 

  34. Ozden E, Turgut AT, Yesil M, Gögüs C, Gögüs O. A new parameter for staging bladder carcinoma: ultrasonographic contact length and height-to-length ratio. J Ultrasound Med. 2007;26(9):1137–42.

    PubMed  Google Scholar 

  35. Wagner B, Nesslauer T, Bartsch G Jr, Hautmann RE, Gottfried HW. Staging bladder carcinoma by three-dimensional ultrasound rendering. Ultrasound Med Biol 2005; 31(3):301–5.

    Article  PubMed  Google Scholar 

  36. Halpern EJ, Contrast-enhanced ultrasound imaging of prostate cancer. Rev Urol. 2006; 8(Suppl 1): S29–S37.

    PubMed  Google Scholar 

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Correspondence to Carlos Nicolau.

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Nicolau, C., Bunesch, L., Sebastia, C. et al. Diagnosis of bladder cancer: contrast-enhanced ultrasound. Abdom Imaging 35, 494–503 (2010). https://doi.org/10.1007/s00261-009-9540-9

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  • DOI: https://doi.org/10.1007/s00261-009-9540-9

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