Abstract
Epstein-Barr virus (EBV) is associated with pathogenesis of several epithelial neoplasms and lymphoproliferative disorders. A certain percentage of gastric carcinomas are associated with EBV. EBV-associated gastric carcinoma is a distinct entity associated with good prognosis. Multiple carcinomas are highly prevalent in EBV-associated gastric carcinomas, and this warrants thorough endoscopic investigation before determining the extent of surgical resection. Therefore, it is important to consider the presence of Epstein-Barr virus in the preoperative CT evaluation of gastric carcinomas. The purpose of this article is to illustrate the CT features of Epstein-Barr virus-associated gastric carcinoma. The surgically resected gastric carcinomas at our institution from 1998 to 2004 were reviewed and were examined for the presence of EBV, and 13 EBV-associated gastric carcinoma lesions were found in 10 patients. The preoperative CT scans were reviewed in these patients. Radiologic features that may suggest the presence of Epstein-Barr virus in gastric carcinoma includes location in the upper part of the stomach, a large thickness-to-width ratio, and a bulky portion projecting from the gastric wall.
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Maeda, E., Akahane, M., Uozaki, H. et al. CT appearance of Epstein-Barr virus-associated gastric carcinoma. Abdom Imaging 34, 618–625 (2009). https://doi.org/10.1007/s00261-008-9444-0
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DOI: https://doi.org/10.1007/s00261-008-9444-0