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Primary thoracic giant cell tumor of bone sensitive to steroids

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Skeletal Radiology Aims and scope Submit manuscript

Abstract

Spinal giant cell tumor of bone (GCTB) is a rare benign, but locally aggressive, entity. We report the case of a 40-year-old man diagnosed with GCTB of the thoracic spine. The only symptom upon presentation was progressive back pain with pain radiating to the chest. Magnetic resonance imaging showed that the soft tissue mass extended posteriorly into the spinal canal, causing severe spinal cord compression. We initially treated this case with Decadron (Fresenius kabi, Bad Homburg vor der Hohe, Germany) for 1 week. This led to a reduction of tumor size and decompression of the spinal cord. To the best of our knowledge, there have been no prior reports of primary GCTB sensitive to steroid therapy within the existing literature.

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Authors and Affiliations

  1. Department of Orthopedics, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, People’s Republic of China

    Huiliang Yang

  2. Department of Orthopaedic Surgery, Orthopaedic Spine and Oncology Services, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

    Huiliang Yang, Gi Hye Im & Joseph H. Schwab

  3. Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

    Gunnlaugur Petur Nielsen

  4. Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

    Arvin Kheterpal

Authors
  1. Huiliang Yang
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  2. Gi Hye Im
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  3. Gunnlaugur Petur Nielsen
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  4. Arvin Kheterpal
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  5. Joseph H. Schwab
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Correspondence to Joseph H. Schwab.

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All procedures performed in studies involving human participants were in accordance with ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

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The authors declare that they have no conflicts of interest.

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Yang, H., Im, G.H., Nielsen, G.P. et al. Primary thoracic giant cell tumor of bone sensitive to steroids. Skeletal Radiol 47, 1431–1435 (2018). https://doi.org/10.1007/s00256-018-2911-y

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  • DOI: https://doi.org/10.1007/s00256-018-2911-y

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