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Biotechnology and pharmacological evaluation of Indian vegetable crop Lagenaria siceraria: an overview

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Abstract

Bottle gourd (Lagenaria siceraria) belongs to the family Cucurbitaceae, which comprises about 118 genera and 825 species. It is an important vegetable crop of India, and its production is influenced by a number of factors viz., environmental, nutritional, cultural operation and use of plant growth regulators. Since, bottle gourd belongs to a medicinal family, it plays a major role in the treatment of several diseases related to the skin and heart. There are several organic chemical compounds including vitamin B complex, pectin, dietary soluble fibres, ascorbic acid, beta-carotene, amino acids and minerals which have been isolated from this species. Therefore, the bottle gourd is considered to have a great impact on therapeutic health benefits. Due to drastic industrialization and urbanization, most of the human beings are facing several ill effects which may lead to death at extreme cases. Hence, the major research area was said to be nanotechnology. Taking into consideration, we have combined nanotechnology field with waste source in the name of green synthesis and planned to cure several diseases, as most of the researchers focused their work on this and succeeded too. The present study is a complete review of L. siceraria that covers the ethnomedical uses, chemical constituents, and pharmacological profile. This study is mainly focused on the antibacterial, hepatoprotective, diuretic and anthelminthic activities.

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Acknowledgments

The author thanks the VIT University for providing all the research facilities and support to carry out research process.

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Authors and Affiliations

  1. Chemistry of Heterocycles & Natural Product Research Laboratory, Organic Chemistry Division, School of Advanced Sciences, VIT University, Vellore, Tamil Nadu, 632014, India

    Selvaraj Mohana Roopan & G. Elango

  2. Biomolecules and Genetics Division, School of Biosciences and Technology, VIT University, Vellore, Tamil Nadu, 632014, India

    V. Devi Rajeswari & V. N. Kalpana

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  1. Selvaraj Mohana Roopan
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  2. V. Devi Rajeswari
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  3. V. N. Kalpana
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  4. G. Elango
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Correspondence to Selvaraj Mohana Roopan.

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This article deals only a review about L. siceraria and its biological activities, so it does not contain any studies with animals performed by any of the authors.

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The authors declare that they have no competing interests.

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Roopan, S.M., Devi Rajeswari, V., Kalpana, V.N. et al. Biotechnology and pharmacological evaluation of Indian vegetable crop Lagenaria siceraria: an overview. Appl Microbiol Biotechnol 100, 1153–1162 (2016). https://doi.org/10.1007/s00253-015-7190-0

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