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Emerging food contaminants: a review

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Abstract

Governments throughout the world are intensifying their efforts to improve food safety. These efforts come as a response to an increasing number of food-safety problems and increasing consumer concerns. In addition, the variety of toxic residues in food is continuously increasing as a consequence of industrial development, new agricultural practices, environmental pollution, and climate change. This paper reviews a selection of emerging contaminants in food, including the industrial organic pollutants perfluorinated compounds (PFCs), polybrominated diphenyl ethers (PBDEs), and nanomaterials; the pharmaceutical residues antibiotics and coccidiostats; and emerging groups of marine biotoxins. The main analytical approaches for their detection and quantification in food will be presented and discussed with special emphasis on biological techniques, when these are feasible. In the last section, a summary of recent publications reporting the concentrations of these compounds in food will be presented and discussed.

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References

  1. Clara M, Scheffknecht C, Scharf S, Weiss S, Gans O (2008) in Water Science and Technology. 58:59–66

    Google Scholar 

  2. Carmosini N, Lee LS (2008) Environ Sci Technol 42:6559–6565

    Article  CAS  Google Scholar 

  3. Kelly BC, Ikonomou MG, Blair JD, Surridge B, Hoover D, Grace R, Gobas FAPC (2009) Environ Sci Technol 43:4037–4043

    Article  CAS  Google Scholar 

  4. Kannan K, Tao L, Sinclair E, Pastva SD, Jude DJ, Giesy JP (2005) Arch Environ Contam Toxicol 48:559–566

    Article  CAS  Google Scholar 

  5. Tittlemier SA, Pepper K, Seymour C, Moisey J, Bronson R, Cao XL, Dabeka RW (2007) J Agric Food Chem 55:3203–3210

    Article  CAS  Google Scholar 

  6. Powley CR, George SW, Ryan TW, Buck RC (2005) Anal Chem 77:6353–6358

    Article  CAS  Google Scholar 

  7. Taniyasu S, Kannan K, Man KS, Gulkowska A, Sinclair E, Okazawa T, Yamashita N (2005) J Chromatogr A 1093:89–97

    Article  CAS  Google Scholar 

  8. Martin JW, Kannan K, Berger U, De Voogt P, Field J, Franklin J, Giesy JP, Harner T, Muir DCG, Scott B, Kaiser M, Järnberg U, Jones KC, Mabury SA, Schroeder H, Simcik M, Sottani C, Van Bavel B, Kärrman A, Lindström G, Van Leeuwen S (2004) Environ Sci Technol 38:248A–255A

    Article  CAS  Google Scholar 

  9. Wang N, Szostek B, Buck RC, Folsom PW, Sulecki LM, Capka V, Berti WR, Gannon JT (2005) Environ Sci Technol 39:7516–7528

    Article  CAS  Google Scholar 

  10. Taniyasu S, Kannan K, Horii Y, Hanari N, Yamashita N (2003) Environ Sci Technol 37:2634–2639

    Article  CAS  Google Scholar 

  11. Guruge KS, Manage PM, Yamanaka N, Miyazaki S, Taniyasu S, Yamashita N (2008) Chemosphere 73:S210–S215

    Article  CAS  Google Scholar 

  12. Yamashita N, Kannan K, Taniyasu S, Horii Y, Okazawa T, Petrick G, Gamo T (2004) Environ Sci Technol 38:5522–5528

    Article  CAS  Google Scholar 

  13. So MK, Taniyasu S, Lam PKS, Zheng GJ, Giesy JP, Yamashita N (2006) Arch Environ Contam Toxicol 50:240–248

    Article  CAS  Google Scholar 

  14. Takino M, Daishima S, Nakahara T (2003) Rapid Commun Mass Spectrom 17:383–390

    Article  CAS  Google Scholar 

  15. Berger U, Haukas M (2005) J Chromatogr A 1081:210–217

    Article  CAS  Google Scholar 

  16. Schwarzer S (2005) E-waste, the hidden side of IT equipment's manufacturing and use

  17. Vetter W, Von Der Recke R, Symons R, Pyecroft S (2008) Rapid Commun Mass Spectrom 22:4165–4170

    Article  CAS  Google Scholar 

  18. von der Recke R, Vetter W (2007) J Chromatogr A 1167:184–194

    Article  Google Scholar 

  19. Shelver WL, Parrotta CD, Slawecki R, Li QX, Ikonomou MG, Barceló D, Lacorte S, Rubio FM (2008) Chemosphere 73:70–75

    Article  Google Scholar 

  20. Xu T, Cho IK, Wang D, Rubio FM, Shelver WL, Gasc AME, Li J, Li QX (2009) Environ Pollut 157:417–422

    Article  CAS  Google Scholar 

  21. Ahn KC, Gee SJ, Tsai HJ, Bennett D, Nishioka MG, Blum A, Fishman E, Hammock BD (2009) Environ Sci Technol 43:7784–7790

    Article  CAS  Google Scholar 

  22. Marchesini GR, Meimaridou A, Haasnoot W, Meulenberg E, Albertus F, Mizuguchi M, Takeuchi M, Irth H, Murk AJ (2008) Toxicol Appl Pharmacol 232:150–160

    Article  CAS  Google Scholar 

  23. Huwe JK, Lorentzsen M, Thuresson K, Bergman A (2002) Chemosphere 46:635–640

    Article  CAS  Google Scholar 

  24. Fernandes A, White S, D'Silva K, Rose M (2004) Talanta 63:1147–1155

    Article  CAS  Google Scholar 

  25. Martínez A, Ramil M, Montes R, Hernanz D, Rubén E, Rodríguez I, Torrijos RC (2005) J Chromatogr A 1072:83–91

    Article  Google Scholar 

  26. Eljarrat E, De La Cal A, Raldua D, Duran C, Barceló D (2004) Environ Sci Technol 38:2603–2608

    Article  CAS  Google Scholar 

  27. Bayen S, Lee HK, Obbard JP (2004) J Chromatogr A 1035:291–294

    Article  CAS  Google Scholar 

  28. Gomara B, Herrero L, Bordajandi LR, González MJ (2006) Rapid Commun Mass Spectrom 20:69–74

    Article  CAS  Google Scholar 

  29. Larrazábal D (2004) Martínez Mª, Eljarrat E, Barceló D, Fabrellas B. J Mass Spectrom 39:1168–1175

    Article  Google Scholar 

  30. Wang Y, Yang R, Wang T, Zhang Q, Li Y, Jiang G (2010) Chemosphere 78:772–777

    Article  CAS  Google Scholar 

  31. Mizukawa K, Takada H, Takeuchi I, Ikemoto T, Omori K, Tsuchiya K (2009) Mar Pollut Bull 58:1217–1224

    Article  CAS  Google Scholar 

  32. Dalläge J, Beens J, Brinkman UAT (2003) J Chromatogr A 1000:69–108

    Article  Google Scholar 

  33. Chaudhry Q, Scotter M, Blackburn J, Ross B, Boxall A, Castle L, Aitken R, Watkins R (2008) Food Addit Contam A Chem Anal Control Expo Risk Assess 25:241–258

    CAS  Google Scholar 

  34. Sanguansri P, Augustin MA (2006) Trends Food Sci Technol 17:547–556

    Article  CAS  Google Scholar 

  35. Kantiani L, Farré M, Sibum M, Postigo C, De Alda ML, Barceló D (2009) Anal Chem 81:4285–4295

    Article  CAS  Google Scholar 

  36. Threlfall EJ, Ward LR, Frost JA, Willshaw GA (2000) Int J Food Microbiol 62:1–5

    Article  CAS  Google Scholar 

  37. Charm SE, Chi R (1988) J Assoc Off Anal Chem 71:304–316

    CAS  Google Scholar 

  38. Gaudin V, Maris P, Fuselier R, Ribouchon JL, Cadieu N, Rault A (2004) Food Addit Contam 21:422–433

    Article  CAS  Google Scholar 

  39. Loomans EEMG, Van Wiltenburg J, Koets M, Van Amerongen A (2003) J Agric Food Chem 51:587–593

    Article  CAS  Google Scholar 

  40. Adrian J, Pinacho DG, Granier B, Diserens JM, Sánchez-Baeza F, Marco MP (2008) Anal Bioanal Chem 391:1703–1712

    Article  CAS  Google Scholar 

  41. FitzGerald SP, O'Loan N, McConnell RI, Benchikh ELO, Kane NE (2007) J AOAC Int 90:334–342

    CAS  Google Scholar 

  42. Pimpitak U, Putong S, Komolpis K, Petsom A, Palaga T (2009) Food Chem 116:785–791

    Article  CAS  Google Scholar 

  43. Wu H, Yang W, Ma J (2008) Chemistry Bulletin / Huaxue Tongbao. 71:394–397

    Google Scholar 

  44. Thavarungkul P, Dawan S, Kanatharana P, Asawatreratanakul P (2007) Biosens Bioelectron 23:688–694

    Article  CAS  Google Scholar 

  45. Gustavsson E, Degelaen J, Bjurling P, Sternesjo A (2004) J Agric Food Chem 52:2791–2796

    Article  CAS  Google Scholar 

  46. Sternesjö A, Gustavsson E (2006) J AOAC Int 89:832–837

    Google Scholar 

  47. Raz SR, Bremer MGEG, Giesbers M, Norde W (2008) Biosens Bioelectron 24:552–557

    Article  Google Scholar 

  48. Weigel S, Pikkemaat MG, Elferink JWA, Mulder PPJ, Huet AC, Delahaut P, Schittko S, Flerus R, Nielen M (2009) Food Addit Contam A Chem Anal Control Expo Risk Assess 26:441–452

    CAS  Google Scholar 

  49. Raz SR, Bremer MGEG, Haasnoot W, Norde W (2009) Anal Chem 81:7743–7749

    Article  Google Scholar 

  50. Jiang Z, Li Y, Liang A, Qin A (2008) Luminescence 23:157–162

    Article  CAS  Google Scholar 

  51. Adrian J, Pasche S, Diserens JM, Sánchez-Baeza F, Gao H, Marco MP, Voirin G (2009) Biosens Bioelectron 24:3340–3346

    Article  CAS  Google Scholar 

  52. Virolainen NE, Pikkemaat MG, Elferink JWA, Karp MT (2008) J Agric Food Chem 56:11065–11070

    Article  CAS  Google Scholar 

  53. Moreno-Bondi MC (2009) Anal Bioanal Chem 395:921–946

    Article  CAS  Google Scholar 

  54. Bohm DA, Stachel CS, Gowik P (2009) J Chromatogr A 1216:8217–8223

    Article  CAS  Google Scholar 

  55. Hsieh SH, Huang HY, Lee S (2009) J Chromatogr A 1216:7186–7194

    Article  CAS  Google Scholar 

  56. Peters RJB, Bolck YJC, Rutgers P, Stolker AAM, Nielen MWF (2009) J Chromatogr A 1216:8206–8216

    Article  CAS  Google Scholar 

  57. Tang Q, Yang T, Tan X, Luo J (2009) J Agric Food Chem 57:4535–4539

    Article  CAS  Google Scholar 

  58. Hammel YA, Mohamed R, Gremaud E, LeBreton MH, Guy PA (2008) J Chromatogr A 1177:58–76

    Article  CAS  Google Scholar 

  59. Sheridan RS, Meola JR (1999) J AOAC Int 82:982–990

    CAS  Google Scholar 

  60. Berrada H, Borrull F, Font G, Marcé RM (2008) J Chromatogr A 1208:83–89

    Article  CAS  Google Scholar 

  61. Kukusamude C, Santalad A, Boonchiangma S, Burakham R, Srijaranai S, Chailapakul O (2010) Talanta 81:486–492

    Article  CAS  Google Scholar 

  62. Van Holthoon F, Mulder PPJ, van Bennekom EO, Heskamp H, Zuidema T, van Rhijn HA (2010) Anal Bioanal Chem 396:3027–3040

    Article  Google Scholar 

  63. Liu W-L, Lee R-J, Lee M-R (2010) Food Chem 121:797–802

    Article  CAS  Google Scholar 

  64. Blasco C, Corcia AD, Picó Y (2009) Food Chem 116:1005–1012

    Article  CAS  Google Scholar 

  65. Olejnik M, Szprengier-Juszkiewicz T, Jedziniak P (2009) J Chromatogr A 1216:8141–8148

    Article  CAS  Google Scholar 

  66. Paschoal JAR, Reyes FGR, Rath S (2009) Anal Bioanal Chem 394:2213–2221

    Article  CAS  Google Scholar 

  67. Zhu Wx, Yang Jz, Wei W, Liu Yf, Zhang Ss (2008) J Chromatogr A 1207:29–37

    Article  CAS  Google Scholar 

  68. Lombardo-Agüí M, García-Campaña AM, Gámiz-Gracia L, Cruces Blanco C (2010) J Chromatogr A 1217:2237–2242

    Article  Google Scholar 

  69. Ge S, Yan M, Cheng X, Zhang C, Yu J, Zhao P, Gao W (2010) J Pharm Biomed Anal 52:615–619

    Article  CAS  Google Scholar 

  70. Li J, Chen L, Wang X, Jin H, Ding L, Zhang K, Zhang H (2008) Talanta 75:1245–1252

    Article  CAS  Google Scholar 

  71. Ciminiello P, Dell'Aversano C, Fattorusso E, Forino M, Magno GS, Tartaglione L, Grillo C, Melchiorre N (2006) Anal Chem 78:6153–6159

    Article  CAS  Google Scholar 

  72. Cheun B, Endo H, Hayashi T, Nagashima Y, Watanabe E (1996) Biosens Bioelectron 11:1185–1191

    Article  CAS  Google Scholar 

  73. Vieytes MR, Cabado AG, Alfonso A, Louzao MC, Botana AM, Botana LM (1993) Anal Biochem 211:87–93

    Article  CAS  Google Scholar 

  74. Hamada-Sato N, Minamitani N, Inaba Y, Nagashima Y, Kobayashi T, Imada C, Watanabe E (2004) Sens mater 16:099–107

    CAS  Google Scholar 

  75. Alfonso A, Vieytes MR, Yasumoto T, Botana LM (2004) Anal Biochem 326:93–99

    Article  CAS  Google Scholar 

  76. Alfonso C, Alfonso A, Vieytes MR, Yasumoto T, Botana LM (2005) Anal Biochem 344:266–274

    Article  CAS  Google Scholar 

  77. Gawley RE, Shanmugasundaram M, Thorne JB, Tarkka RM (2005) Toxicon 45:783–787

    Article  CAS  Google Scholar 

  78. (1991) Council Directive 91/492/EEC of 15 July 1991, laying down the health conditions for the production and the placing on the market of live bivalve molluscs

  79. Espiña B, Cagide E, Louzao MC, Fernandez MM, Vieytes MR, Katikou P, Villar A, Jaen D, Maman L, Botana LM (2009) Biosci Rep 29:13–23

    Article  Google Scholar 

  80. Fonfría ES, Vilariño N, Espiña B, Louzao MC, Álvarez M, Molga J, Aríoz R, Botana LM (2010) Anal Chim Acta 657:75–82

    Article  Google Scholar 

  81. Stewart I, Eaglesham GK, Poole S, Graham G, Paulo C, Wickramasinghe W, Sadler R, Shaw GR (2009) Toxicon, article in press

  82. Ciminiello P, Dell'Aversano C, Fattorusso E, Forino M, Tartaglione L, Boschetti L, Rubini S, Cangini M, Pigozzi S, Poletti R (2010) Toxicon 55:280–288

    Article  CAS  Google Scholar 

  83. González AV, Rodríguez-Velasco ML, Ben-Gigirey B, Botana LM (2006) Toxicon 48:1068–1074

    Article  Google Scholar 

  84. Villar-González A, Rodríguez-Velasco ML, Ben-Gigirey B, Botana LM (2007) Toxicon 49:1129–1134

    Article  Google Scholar 

  85. Amzil Z, Sibat M, Royer F, Masson N, Abadie E (2007) Mar Drugs 5:168–179

    CAS  Google Scholar 

  86. Gerssen A, Mulder PPJ, McElhinney MA, de Boer J (2009) J Chromatogr A 1216:1421–1430

    Article  CAS  Google Scholar 

  87. Guerra P, de la Cal A, Marsh G, Eljarrat E, Barceló D (2009) J Hydrol 369:360–367

    Article  CAS  Google Scholar 

  88. Adou K, Bontoyan WR, Sweeney PJ (2001) J Agric Food Chem 49:4153–4160

    Article  CAS  Google Scholar 

  89. So MK, Miyake Y, Yeung WY, Ho YM, Taniyasu S, Rostkowski P, Yamashita N, Zhou BS, Shi XJ, Wang JX, Giesy JP, Yu H, Lam PKS (2007) Chemosphere 68:2085–2095

    Article  CAS  Google Scholar 

  90. Llorca M, Farré M, Picó Y, Barceló D (2009) J Chromatogr A 1216:7195–7204

    Article  CAS  Google Scholar 

  91. Eljarrat E, Barceló D (2004) TrAC, Trends Anal Chem 23:727–736

    Article  CAS  Google Scholar 

  92. Peres GT, Rath S, Reyes FGR (2010) Food Control 21:620–625

    Article  CAS  Google Scholar 

  93. Cháfer-Pericás C, Maquieira A, Puchades R, Miralles J, Moreno A, Pastor-Navarro N, Espinos F (2010) Anal Chim Acta 662:177–185

    Article  Google Scholar 

  94. Costi EM, Sicilia MD, Rubio S (2010) J Chromatogr A 1217:1447–1454

    Article  CAS  Google Scholar 

  95. Maher HM, Youssef RM, Khalil RH, El-Bahr SM (2008) J Chromatogr B Anal Technol Biomed Life Sci 876:175–181

    Article  CAS  Google Scholar 

  96. Alfonso C, Alfonso A, Pazos MJ, Vieytes MR, Yasumoto T, Milandri A, Poletti R, Botana LM (2007) Anal Biochem 363:228–238

    Article  CAS  Google Scholar 

  97. Gawley RE, Mao H, Haque MM, Thorne JB, Pharr JS (2007) J Org Chem 72:2187–2191

    Article  CAS  Google Scholar 

  98. Berger U, Glynn A, Holmstrom KE, Berglund M, Ankarberg EH, Tarnkvist A (2009) Chemosphere 76:799–804

    Article  CAS  Google Scholar 

  99. Schuetze A, Heberer T, Effkemann S, Juergensen S (2010) Chemosphere 78:647–652

    Article  CAS  Google Scholar 

  100. Gao Z, Xu J, Xian Q, Feng J, Chen X, Yu H (2009) Chemosphere 75:1273–1279

    Article  CAS  Google Scholar 

  101. Ciminiello P, Dell'Aversano C, Fattorusso E, Magno S, Tartaglione L, Cangini M, Pompei M, Guerrini F, Boni L, Pistocchi R (2006) Toxicon 47:597–604

    Article  CAS  Google Scholar 

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Acknowledgements

This work was supported by the Spanish Ministry of Science and Innovation, through the project CEMAGUA (CGL2007-64551/HID). Waters is acknowledged for providing the SPE cartridges. Lina Kantiani acknowledges the Generalitat de Catalunya (2009FI_B 00660) and the Alexander S. Onassis foundation (F-ZD 09/2007-2008).

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Authors and Affiliations

  1. Department of Environmental Chemistry, IDAEA-CSIC, 08034, Barcelona, Spain

    Lina Kantiani, Marta Llorca, Josep Sanchís, Marinella Farré & Damià Barceló

  2. King Saud University, Riyadh, 11451, Saudi Arabia

    Damià Barceló

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  1. Lina Kantiani
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  2. Marta Llorca
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  3. Josep Sanchís
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  4. Marinella Farré
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  5. Damià Barceló
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Correspondence to Marinella Farré.

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Published in the special issue on Focus on Bioanalysis with Guest Editors Antje J. Baeumner, Günter Gauglitz, and Frieder W. Scheller.

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Kantiani, L., Llorca, M., Sanchís, J. et al. Emerging food contaminants: a review. Anal Bioanal Chem 398, 2413–2427 (2010). https://doi.org/10.1007/s00216-010-3944-9

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