Abstract
Water-soluble vitamins include the B-group vitamins and vitamin C. In order to correctly monitor water-soluble vitamin content in fortified foods for compliance monitoring as well as to establish accurate data banks, an accurate and precise analytical method is a prerequisite. For many years microbiological assays have been used for analysis of B vitamins. However they are no longer considered to be the gold standard in vitamins analysis as many studies have shown up their deficiencies. This review describes the current status of analytical methods, including microbiological assays and spectrophotometric, biosensor and chromatographic techniques. In particular it describes the current status of the official methods and highlights some new developments in chromatographic procedures and detection methods. An overview is made of multivitamin extractions and analyses for foods and supplements.
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References
Ball GFM (2005) Vitamins in foods, analysis, bioavailability and stability. CRC, Boca Raton
Russel LF (2004) In: Nollet LML (ed) Handbook of food analysis, vol.1, chap 16, 2nd edn. Dekker, New York
Konings E (2006) J AOAC Int 89:85–288
Konings E (2007) J AOAC Int 90:21B–25B
Arcot J, Shrestha A (2005) Trends Food Sci Technol 16:253–266
Lynch PLM, Young IS (2000) J Chromatogr A 881:267–284
AOAC International (2006) Official methods of AOAC international, 18th edn. AOAC International, Gaithersburg
Kall MA (2003) Food Chem 82:315–327
DeVries JW, Rader JI, Keagy PM, Hudson CA (2005) J AOAC Int 88:5–15
Anonymous (2003) EN 14131:2003. Foodstuffs: determination of folate by microbiological assay
Chun J, Martin JA, Chen L, Lee J, Ye L, Eitenmiller RR (2006) J Food Compos Anal 19:182–187
AACC (2000) Approved methods of American Association Cereal Chemists, 10th edn. American Association Cereal Chemists, St Paul
Koontz JL, Phillips KM, Wunderlich KM, Exler J, Holden JM, Genhardt SE, Haytowitz DB (2005) J AOAC Int 88:805–813
Staggs CG, Sealey WM, McCabe BJ, Teague AM, Mock DM (2004) J Food Compos Anal 17:767–776
Kalman A, Caelen I, Svorc J (2006) J AOAC Int 89:819–825
Indyk HE, Evans EA, Caselunghe MCB, Persson BS, Finglas PM, Woollard DC, Filonzi EL (2000) J AOAC Int 83:1141–1148
Caselunghe MB, Lindeberg J (2000) Food Chem 70:523–532
Haughey SA, O’Kane AA, Baxter GA (2005) J AOAC Int 88:1008–1014
Kalman A, Caelen I, Trisconi MJ (2003) New Food 6:26–31
Indyk HE, Persson BS, Caselunghe MCB, Moberg A, Filonzi E, Woollard DC (2002) J AOAC Int 85:72–81
Wahlstrom E (2004) Eur Food Sci Technol June 22–23
Arcot J, Shrestha AK, Gusanov U (2002) Food Control 13:245–252
Anonymous (2003) EN 14122:2003. Foodstuffs—determination of vitamin B1 by HPLC
Analytical Methods Committee (2000) Analyst 125:353–360
Arella F, Lahely S, Bourguignon JB, Hasselmann C (1996) Food Chem 56:81–86
Xueyan T, Cronin DA, Brunton NP (2006) J Food Compos Anal 19:831–837
Anonymous (2003) EN 15152:2003. Foodstuffs—determination of vitamin B2 by HPLC
Cataldi TRI, Nardiello D, Carrara V, Ciriello R, De Benedetto GE (2003) Food Chem 82:309–314
Ndaw S, Bergaentzleé M, Aoudé-Werner D, Hasselmann C (2002) Food Chem 78:129–134
La Croix DE, Wolf WR, Chase GW (2002) J AOAC Int 85:654–664
LaCroix DE, Wolf WR, Kwansa AL (2005) Cereal Chem 82:277–281
Lahely S, Bergaentzle M, Hasselmann C (1999) Food Chem 65:129–133
Rose-Sallin C, Blake CJ, Genoud D, Tagliaferri EG (2001) Food Chem 73:473–480
Saccani G, Tanzi T, Mallozzi S, Cavalli S (2005) Food Chem 92:373–379
Windahl KL, Trenerry VC, Ward CM (1998) Food Chem 65:263–270
Woollard DC, Indyk HE, Christiansen SK (2000) Food Chem 69:201–208
Mittermayr R, Kalman A, Trisconi MJ, Heudi O (2004) J Chromatogr A 1032:1–6
Choi Y-J, Jang J-H, Park H-K, Park K-S, Koo Y-E (2004) J Korean Soc Food Sci Nutr 33:381–385
Pakin C, Bergaentzlé M, Hubscher V, Aoudé-Werner D, Hasselmann C (2004) J Chromatogr A 1035:87–95
Rychlik M (2003) Analyst 128(7):832–837
Rychlik M, Roth-Maier D (2005) Int J Vit Nutr Res 75:218–223
Sadecka J, Karasova G, Polonsky J (2003) Eur Food Res Technol 216:440–444
Anonymous (2002) EN 14164:2002. Foodstuffs. Determination of vitamin B6 by HPLC
Mann DL, Chase GW Jr, Eitenmiller RR (2001) J AOAC Int 8:1593–1599
Mann DL, Ware GM, Bonnin E, Eitenmiller RR (2005) J AOAC Int 88:30–37
Anonymous (2005) EN 14663:2005. Foodstuffs. Determination of vitamin B6 (including its glycosylated forms) by HPLC
Vinas P, Balsalobre N, Lopez-Erroz C, Hernandez-Cordoba M (2004) Chromatographia 59:381–386
Gatti R, Gioia MG (2005) Anal Chim Acta 538:135–141
Lahely S, Ndaw S, Arella F, Hasselmann C (1999) Food Chem 65:253–258
Arella F, Deborde JL, Bourguignon JB, Bergaentzle M, Ndaw S, Hasselmann C (2000) Ann Falsif Expert Chim Toxicol 93:193–200
Thompson LB, Schmitz DJ, Shang-Jing P (2006) J AOAC Int 89:1515–1518
Holler U, Wachter F, Wehrli C, Fizet C (2006) J Chromatogr B 831:8–16
Perez-Ruiz T, Martinez-Lozano C, Sanz A, Bravo E (2003) Chromatographia 58:757–762
Quinlivan EP, Hanson AD, Gregory JF (2006) Anal Biochim 348:163–184
Doherty RF, Beecher GR (2003) J Agric Food Chem 51:354–361
Thomas PM, Flanagan VP, Pawlosky RJ (2003) J Agric Food Chem 51:1293–1296
Nilsson C, Johansson M, Yazynina E, Stralsjo L, Jastrebova J (2004) Eur Food Res Technol 219:199–204
Straljo L, Ahlin H, Witthöft CM, Jastrebova J (2003) Eur Food Res Technol 216:264–269
Food Standards Agency (2004) Development and validation of an HPLC method for the determination of folate in food. Food Standards Agency, London
Ndaw S, Bergaentzle M, Aoudé-Werner D, Lahély S, Hasselmann C (2001) J Chromatogr A 928:77–90
Gujska E, Kuncewicz A (2005) Eur Food Res Technol 221:208–213
Perez-Prieto S, Cancho-Grande B, Garcia-Falcon S, Simal-Gandara J (2006) Food Control 17:900–904
Pawlosky RJ, Flanagan VP, Doherty R (2003) J Agric Food Chem 51:3726–3730
Rychlik M (2003) Analyst 128:832–837
Pawlowsky RJ, Hertrampf E, Flanagan VP, Thomas PM (2003) J Food Compos Anal 16:281–286
Freisleben A, Schieberle P, Rychlik M (2003) Anal Bioanal Chem 376:149–156
Freisleben A, Schieberle P, Rychlik M (2003) Anal Biochem 315:247–255
Rychlik M, Freisleben A (2002) J Food Compos Anal 15:399–409
Rychlik M (2003) Anal Chim Acta 495:133–141
Rychlik (2004) J Food Compos Anal 17:475–483
Rychlik M (2006) Ernahrung 30:53–59
Matella NJ, Braddock RJ, Gregory JF III, Goodrich RM (2005) J Agric Food Chem 53:2268–2274
Zhao S, Yuan H, Xie C, Xiao D (2006) J Chromatogr A 1107:290–293
Aurora-Prado MS, Silva CA, Tavares MFM, Altria KD (2004) J Agric Food Chem 1051:291–296
Heudi O, Kilinc T, Fontannaz P, Marley E (2006) J Chromatogr A 1101:63–68
Pakin C, Bergaentzle M, Aoudé-Werner D, Hasselmann C (2005) J Chromatogr A 1081:182–189
Wongyai S (2000) J Chromatogr A 870:217–229
Luo X, Chen B, Ding L, Tang F, Yao S (2006) Anal Chim Acta 562:185–189
Anonymous (2003) EN 14130:2003. Foodstuffs. Determination of vitamin C by HPLC
Fontannaz P, Kilinc T, Heudi O (2006) Food Chem 94:626–631
Parpinello GP, Mattioli A, Lupini S, Versari A (2006) Ind Bev 35:231–233
Law WS, Kuban P, Zhao JH, Li SFY, Hauser PC (2005) Electrophoresis 26:4648–4655
Zafra-Gomez A, Garballo A, Morales JC, Garcia-Ayuso LE (2006) J Agric Food Chem 54:4531–4536
Chase GW Jr, Landen WO, Eitenmiller RR, Soliman AGM (1992) J AOAC Int 75:561–565
Albala-Hurtado S, Veciana-Noigués MT, Izquierdo-Pulido M, Mariné-Font A (1997) J Chromatogr A 778:247–253
Woollard DC, Indyk HE (2002) J AOAC Int 85:945–951
Vinas P, Lopez-Erroz C, Balsalobre N, Hernandez-Cordoba M (2003) J Chromatogr A 1007:77–84
Ndaw S, Bergaentzlé D, Aoudé-Werner D, Hasselmann C (2000) Food Chem 71:129–138
Moreno P, Salvado V (2000) J Chromatogr A 870:207–215
Li HB, Chen F (2001) J Sep Sci 24:271–274
Ramos-Martos N, Aguirre-Gomez F, Molina-Diaz A, Capitan-Vallvey LF (2001) J AOAC Int 84:676–683
Klejdus B, Petrlova J, Potesil D, Adam V, Mikelova R, Vacek J, Kizek R, Kuban V (2004) Anal Chim Acta 520:57–67
Marszall ML, Lebiedzinska A, Czarnowski W, Szefer P (2005) J Chromatogr A 1094:91–98
Monferrer-Pons L, Capella-Peiro E, Gil-Agusti M, Esteve-Romero J (2003) J Chromatogr A 984:223–231
Ghorbani AR, Momenbeik F, Khorasani JH, Amini MK (2004) Anal Bioanal Chem 379:439–444
Heudi O, Kilinc T, Fontannaz P (2005) J Chromatogr A 1056:3–12
Chen P, Wolf WR (2007) Anal Bioanal Chem (in press)
Chen Z, Chen B, Yao S (2006) Anal Chim Acta 569:169–175
Delgado-Zamarreno MM, Gonzalez-Maza A, Sanchez-Perez A, Carabias-Martinez R (2002) J Chromatogr A 953:257–262
Sanchez JM, Salvado V (2002) J Chromatogr A 950:211–247
Okamoto H, Nakajima T, Ito Y (2003) J Chromatogr A 986:153–162
Schreiner M, Razzazi E, Luf W (2003) Nahrung 47:243–247
Aranda M, Morlock G (2006) J Chromatogr A 1131:253–260
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Blake, C.J. Analytical procedures for water-soluble vitamins in foods and dietary supplements: a review. Anal Bioanal Chem 389, 63–76 (2007). https://doi.org/10.1007/s00216-007-1309-9
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DOI: https://doi.org/10.1007/s00216-007-1309-9