Skip to main content

Advertisement

Log in

Genotoxic damage in the oral mucosal cells of subjects carrying restorative dental fillings

  • Letter to the Editor
  • Published:
Archives of Toxicology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Blasiak J, Synowiec E, Tarnawska J, Czarny P, Poplawski T, Reiter RJ (2012) Dental methacrylates may exert genotoxic effects via the oxidative induction of DNA double strand breaks and the inhibition of their repair. Mol Biol Rep 39:7487–7496

    Article  PubMed  CAS  Google Scholar 

  • Di Pietro A, Visalli G, La Maestra S, Micale R, Baluce B, Matarese G, Cingano L, Scoglio ME (2008) Biomonitoring of DNA damage in peripheral blood lymphocytes of subjects with dental restorative fillings. Mutat Res 650:115–122

    Article  PubMed  Google Scholar 

  • Poplawski T, Pawlowska E, Wisniewska-Jarosinska M, Ksiazek D, Wozniak K, Szczepanska J, Blasiak J (2009) Cytotoxicity and genotoxicity of glycidyl methacrylate. Chem Biol Interact 180:69–78

    Article  PubMed  CAS  Google Scholar 

  • Reichl FX, Simon S, Esters M, Seiss M, Kehe K, Kleinsasser N, Hickel R (2006) Cytotoxicity of dental composite (co)monomers and the amalgam component Hg2+ in human gingival fibroblasts. Arch Toxicol 80:645–672

    Google Scholar 

  • Rothfuss A, Vonk R, Schweinfurth H (2013) The evidence of genotoxic damage in the oral mucosa due to dental fillings is very questionable. Arch Toxicol 87:1155–1156

    Article  PubMed  CAS  Google Scholar 

  • Visalli G, Baluce B, La Maestra S, Micale RT, Cingano L, De Flora S, Di Pietro A (2013) Genotoxic damage in the oral mucosa cells of subjects carrying restorative dental fillings. Arch Toxicol 87:179–187

    Article  PubMed  CAS  Google Scholar 

  • Wiklund SJ, Agurell E (2003) Aspects of design and statistical analysis in the Comet assay. Mutagenesis 18:167–175

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Giuseppa Visalli or Silvio De Flora.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Visalli, G., Baluce, B., La Maestra, S. et al. Genotoxic damage in the oral mucosal cells of subjects carrying restorative dental fillings. Arch Toxicol 87, 2247–2248 (2013). https://doi.org/10.1007/s00204-013-1155-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00204-013-1155-9

Keywords

Navigation