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Incontinence-specific quality of life measures used in trials of treatments for female urinary incontinence: a systematic review

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Abstract

This systematic review examined the use of incontinence-specific quality of life (QOL) measures in clinical trials of female incontinence treatments, and systematically evaluated their quality using a standard checklist. Of 61 trials included in the review, 58 (95.1%) used an incontinence-specific QOL measure. The most commonly used were IIQ (19 papers), I-QoL (12 papers) and UDI (9 papers). Eleven papers (18.0%) used measures which were not referenced or were developed specifically for the study. The eight QOL measures identified had good clinical face validity and measurement properties. We advise researchers to evaluate carefully the needs of their specific study, and select the QOL measure that is most appropriate in terms of validity, utility and relevance, and discourage the development of new measures. Until better evidence is available on the validity and comparability of measures, we recommend that researchers consider using IIQ or I-QOL with or without UDI in trials of incontinence treatments.

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Authors and Affiliations

  1. Departments of Obstetrics and Gynaecology, Family Medicine and Community Health Sciences, University of Calgary, Canada

    Sue Ross

  2. Department of Health Policy, Management and Evaluation, University of Toronto, Canada

    Sue Ross

  3. Maternal, Infant and Reproductive Health Research Unit, Centre for Research in Women’s Health, Sunnybrook and Women’s College Health Sciences Centre, Toronto, Canada

    Sue Ross & Amalia Karahalios

  4. Department of Obstetrics and Gynaecology, University of Toronto, Canada

    Dana Soroka & Harold P. Drutz

  5. Department of Obstetrics and Gynaecology, Saint Michael’s Hospital, Toronto, Canada

    Dana Soroka

  6. Health Services Research Unit, University of Aberdeen, UK

    Cathryn M. A. Glazener

  7. Rehabilitation Teaching and Research Unit, Department of Medicine, Wellington School of Medicine and Health Sciences, University of Otago, New Zealand

    E. Jean C. Hay-Smith

  8. Section of Urogynecology and Reconstructive Pelvic Surgery, Department of Obstetrics and Gynaecology, Mount Sinai Hospital, Toronto, Canada

    Harold P. Drutz

  9. Department of Obstetrics and Gynaecology, Foothills Medical Centre, 4th Floor, North Tower, 1403-29 Street NW, Calgary, AB, T2N 2T9, Canada

    Sue Ross

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Correspondence to Sue Ross.

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Ross, S., Soroka, D., Karahalios, A. et al. Incontinence-specific quality of life measures used in trials of treatments for female urinary incontinence: a systematic review. Int Urogynecol J 17, 272–285 (2006). https://doi.org/10.1007/s00192-005-1357-7

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