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Correlation between valsalva leak point pressure and maximal urethral closure pressure in women with stress urinary incontinence

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Abstract

This study analyzed the relationship between valsalva leak point pressure (VLPP) and maximal urethral closure pressure (MUCP) in women with stress urinary incontinence. One hundred sixty-one patients were selected with diagnosis of mixed or stress urinary incontinence. During urodynamics we measured VLPP and MUCP. Patients were gathered according to VLPP and analysis of variance (ANOVA) was performed. Pearson’s correlation coefficient and linear regression were also utilized. The group with VLPP under 60 cm H2O had mean MUCP of 44.5 cm H20; the group with VLPP between 60 and 90 cm H2O had mean MUCP of 54.3 cm H2O; and the group with VLPP over 90 cm H2O had mean MUCP of 60.1 cm H2O. We observed correlation between MUCP and VLPP when we used Pearson’s correlation coefficient (r=0.22) and linear regression (p<0.05). There was weak correlation between MUCP and VLPP, and MUCP was significantly lower in patients with leak point pressure inferior to 60 cm H2O.

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Correspondence to Paulo Cezar Feldner Jr.

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Editorial Comment: This is a retrospective study of 161 female patients with stress urinary incontinence in which the authors analyze the relationship between urodynamic valsalva leak point pressure (VLPP) and maximal urethral closure pressure (MUCP). In analyzing their data with Pearson’s correlation coefficient and linear regression, the authors found a weak correlation between VLPP and MUCP. In addition, they found a significantly lower MUCP in patients with VLPP less than 60. The authors conclude that MUCP values less than 45 cm H2O are not sensitive in diagnosing intrinsic sphincter deficiency. Although this study supports the known correlation between VLPP and MUCP, it adds little new information to the literature. This subject has previously been studied and evaluated and numerous published articles have already confirmed this correlation. It is already generally accepted that the diagnosis of intrinsic sphincter deficiency should be based on a compilation of factors including patient history, urodynamic, anatomic, and clinical severity criteria

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Feldner, P.C., Bezerra, L.R.P.S., de Castro, R.A. et al. Correlation between valsalva leak point pressure and maximal urethral closure pressure in women with stress urinary incontinence. Int Urogynecol J 15, 194–197 (2004). https://doi.org/10.1007/s00192-004-1130-3

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  • DOI: https://doi.org/10.1007/s00192-004-1130-3

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