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Chronische Wunde

Neue Wege in Forschung und Therapie

Chronic wounds

Novel approaches in research and therapy

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Zusammenfassung

Wundheilungsmechanismen können durch unterschiedliche Grunderkrankungen behindert werden und den Zustand einer chronisch schlecht heilenden Wunde entwickeln. Für eine effiziente Therapiestrategie ist es notwendig, die Grunderkrankung zu identifizieren, zu behandeln und die pathologische Wundheilung gezielt zu normalisieren. Hierzu sind detaillierte Kenntnisse über die ablaufenden zellulären und molekularen Mechanismen notwendig. In dieser Übersicht sollen neue Erkenntnisse über die normale und pathologische Wundheilung und die sich daraus ergebenden konservativen Therapieansätze dargestellt werden.

Abstract

Underlying disease may impair normal wound healing, leading to chronic, poorly healing wounds. Efficient treatment strategies require identification and treatment of the underlying disease as well as directed correction of the wound healing defect. A thorough knowledge of tissue repair mechanisms at the cellular and molecular level will help to achieve these goals. This review focuses on new developments in wound healing research and the resulting non-operative therapeutic implications.

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Interessenkonflikt

Der korrespondierende Autor weist auf folgende Beziehungen hin: S.A. Eming. T. Krieg Beratertätigkeit bei Bayer Innovation GmbH.

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Eming, S., Kaufmann, J., Löhrer, R. et al. Chronische Wunde. Hautarzt 58, 939–944 (2007). https://doi.org/10.1007/s00105-007-1402-1

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