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Immunological features of polymyositis/dermatomyositis

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Conclusion

Consideration of the clinical, pathological and immunological features in PM reveals that a variety of immunological processes, both cellular and humoral, are occurring and may produce widespread damage to other organs as well as skeletal muscle. The basis for the disorder appears to be a failure of immune regulation, most likely associated with a genetic susceptibility.

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Behan, W.M.H., Behan, P.O. Immunological features of polymyositis/dermatomyositis. Springer Semin Immunopathol 8, 267–293 (1985). https://doi.org/10.1007/BF00197300

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